Iodine-Mediated Thioetherification of Alcohols with Disulfides or NaSH under Microwave Irradiation



An efficient and novel method for the thioetherification of an alcohol with disulfides or NaSH under microwave irradiation is presented. In the presence of iodine, a variety of alcohols were smoothly S-alkylated with disulfides or NaSH to give the corresponding thioethers in moderate to excellent yields.