Iodine-Mediated Thioetherification of Alcohols with Disulfides or NaSH under Microwave Irradiation

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Abstract

An efficient and novel method for the thioetherification of an alcohol with disulfides or NaSH under microwave irradiation is presented. In the presence of iodine, a variety of alcohols were smoothly S-alkylated with disulfides or NaSH to give the corresponding thioethers in moderate to excellent yields.

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