Synthesis of 2-Aminoindole Derivatives with Hantzsch Ester Catalyzed by Pd/C

Authors

  • Ruiguang Xing,

    Corresponding author
    1. College of Rare Earth, Inner Mongolia University of Science & Technology, Baotou, Inner Mongolia 014010, China
    • College of Rare Earth, Inner Mongolia University of Science & Technology, Baotou, Inner Mongolia 014010, China, Tel.: 0086-472-5951536; Fax: 0086-472-5951536
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  • Qiuping Tian,

    1. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, China
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  • Qiang Liu,

    1. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, China
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  • Yanan Li

    1. College of Rare Earth, Inner Mongolia University of Science & Technology, Baotou, Inner Mongolia 014010, China
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Abstract

Catalytic hydrogenation of 2-cyano-2-(2-nitrophenyl)acetates bearing an electron withdrawing substituent to the nitrile, using Hantzsch ester catalyzed by Pd/C, affords 2-aminoindoles in good to excellent yields.

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