Organocatalytic Enantioselective Dehydrogenative α-Alkylation of Aldehydes with Benzylic Compounds

Authors

  • Fen Huang,

    1. School of Chemistry and Chemical Engineering, University of South China, Hengyang, Hunan 421001, China
    2. Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China
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  • Lubin Xu,

    1. College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, Shandong 266109, China
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  • Jian Xiao

    Corresponding author
    1. College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, Shandong 266109, China
    2. Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, Liaoning 116023, China
    • College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, Shandong 266109, China, Tel.: 0086-532-88030147
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Abstract

The highly enantioselective cross-dehydrogenative coupling of aldehydes with benzylic compounds has been developed as an efficient and rapid protocol for synthesis of enantioriched α-alkylated aldehydes.

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