Decarboxylative Alkylation of β-Keto Acids with Isochromans under Oxidative Conditions
Article first published online: 27 DEC 2012
Copyright © 2013 SIOC, CAS, Shanghai & WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Chinese Journal of Chemistry
Special Issue: Dedicated to the Memory of Professor Wei-Shan Zhou
Volume 31, Issue 1, pages 37–39, January, 2013
How to Cite
Chen, Y. and Tian, S.-K. (2013), Decarboxylative Alkylation of β-Keto Acids with Isochromans under Oxidative Conditions. Chin. J. Chem., 31: 37–39. doi: 10.1002/cjoc.201200994
- Issue published online: 18 JAN 2013
- Article first published online: 27 DEC 2012
- Manuscript Accepted: 27 NOV 2012
- Manuscript Received: 13 OCT 2012
- the National Natural Science Foundation of China. Grant Number: 21232007 and 21172206
- the National Basic Research Program of China (973 Program). Grant Number: 2010CB833300
- the Program for Changjiang Scholars and Innovative Research Team in University. Grant Number: IRT1189
- 3cSynlett, 1991, 359.; ; .
- 8For the use of oxoammonium salts as the cooxidants, see:
- 8kSynlett, 2009, 138.; ; ; .
- 9For a review, see: Organic Reactions, Ed.: Denmark, S. E., Wiley, New York, 2009, Vol. 74, p. 103.; ; , In
- 10The standard reaction conditions were not applicable to acyclic ethers. For example, no alkylation product was obtained from the reaction of dibenzyl ether with β-keto acid 1a in the presence of 1. 2 equiv. of T+PF−6. In this case, dibenzyl ether was consumed completely and benzaldehyde was obtained in 20% yield.