Sidearm as a Control in the Asymmetric Ring Opening Reaction of Donor-Acceptor Cyclopropane
Article first published online: 4 APR 2014
Copyright © 2014 SIOC, CAS, Shanghai & WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Chinese Journal of Chemistry
Special Issue: Dedicated to Professor Chengye Yuan and Professor Li-Xin Dai on the occasion of their 90th birthdays (I).
Volume 32, Issue 8, pages 669–672, August, 2014
How to Cite
Kang, Q., Wang, L., Zheng, Z., Li, J. and Tang, Y. (2014), Sidearm as a Control in the Asymmetric Ring Opening Reaction of Donor-Acceptor Cyclopropane. Chin. J. Chem., 32: 669–672. doi: 10.1002/cjoc.201400053
- Issue published online: 26 AUG 2014
- Article first published online: 4 APR 2014
- Manuscript Accepted: 6 MAR 2014
- Manuscript Received: 26 JAN 2014
- the Natural Science Foundation of China. Grant Number: 21121062, and 21272250
- Chinese Academy of Sciences
- ring opening;
A new type of trisoxazoline and bisthiazoline based ligands have been developed,which are absent of chiral motif on the parent skeleton and containa chiral backbone on sidearm. The ligands promote the amine nucleophilic ring opening reaction of 1,1-cyclopropane diesters smoothly, furnishing the γ-amino acid derivatives in high yield with moderate to good enantioselectivity.