SEARCH

SEARCH BY CITATION

Keywords:

  • allylboration;
  • bukuchiol;
  • meroterpenoid;
  • pot-economy;
  • quaternary carbon

Abstract

A rapid synthetic route toward (±)-Bakuchiol is presented in 29% overall yield. After the sole all-carbon quaternary carbon center is created via allylboration of 2-aryl acetaldehyde, a "Pot-Economy" approach including mesylation, elimination, and desilylation was realized in the presence of tBuOK under ambient temperature to provide (±)-Bakuchiol.