Synthesis, QSAR Study and Optimization of Propiophenone Oxime Derivatives (pages 33–42)
Liang CHEN, Ying HUANG, Wei XIE, Jin CAO, Changchun NI, Zhou SHEN, Xiuli LI, Yibin ZHANG, Tianxiang SHEN, Fei YU, Bin LIU, Liping YUAN and Jianhua YAO
Article first published online: 20 JAN 2009 | DOI: 10.1002/cjoc.200990023
Two lead compounds were designed based on the CoMFA and CoMSIA models constructed by experimental data. Their predicted and observed bioactivities are corresponding.