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Effects of the Aging Process on Left Ventricular Systolic and Diastolic Synchronicity Indexes: Insights From 160 “Completely” Healthy Volunteers

  1. Hyung-Kwan Kim MD, PhD*,
  2. Dae-Won Sohn MD,
  3. Sung-A Chang MD,
  4. Keun-Ho Park MD,
  5. Jin-Shik Park MD,
  6. Yong-Jin Kim MD,
  7. Byung-Hee Oh MD,
  8. Young-Bae Park MD

Article first published online: 23 DEC 2010

DOI: 10.1002/clc.20477

Issue

Clinical Cardiology

Clinical Cardiology

Volume 33, Issue 12, pages E24–E31, December 2010

Additional Information

How to Cite

Kim, H.-K., Sohn, D.-W., Chang, S.-A., Park, K.-H., Park, J.-S., Kim, Y.-J., Oh, B.-H. and Park, Y.-B. (2010), Effects of the Aging Process on Left Ventricular Systolic and Diastolic Synchronicity Indexes: Insights From 160 “Completely” Healthy Volunteers. Clin Cardiol, 33: E24–E31. doi: 10.1002/clc.20477

Author Information

  1. Division of Cardiology, Department of Internal Medicine, Cardiovascular Center, Seoul National University Hospital, Seoul, Korea

*Division of Cardiology, Department of Internal Medicine, Cardiovascular Center, Seoul National University, College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul, 110–744, Korea.

Publication History

  1. Issue published online: 23 DEC 2010
  2. Article first published online: 23 DEC 2010

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REFERENCES

  • 1
    Cazeau S, Leclercq C, Lavergne T, et al; Multisite Stimulation in Cardiomyopathies (MUSTIC) Study Investigators. Effects of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. N Engl J Med 2001; 344: 873–880.
  • 2
    Bleeker GB, Schalij MJ, Molhoek SG, et al. Relationship between QRS duration and left ventricular dyssynchrony in patients with end-stage heart failure. J Cardiovasc Electrophysiol 2004; 15: 544–549.
    Direct Link:
  • 3
    Yu CM, Fung JW, Zhang Q, et al. Tissue Doppler imaging is superior to strain rate imaging and postsystolic shortening on the prediction of reverse remodeling in both ischemic and nonischemic heart failure after cardiac resynchronization therapy. Circulation 2004; 110: 66–73.
  • 4
    Bax JJ, Bleeker GB, Marwick TH, et al. Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy. J Am Coll Cardiol 2004; 44: 1834–1840.
  • 5
    Gorcsan J III, Kanzaki H, Bazaz R, Dohi K, Schwartzman D. Usefulness of echocardiographic tissue synchronization imaging to predict acute response to cardiac resynchronization therapy. Am J Cardiol 2004; 93: 1178–1181.
  • 6
    Yu CM, Lin H, Zhang Q, Sanderson JE. High prevalence of left ventricular systolic and diastolic asynchrony in patients with congestive heart failure and normal QRS duration. Heart 2003; 89: 54–60.
  • 7
    Yu CM, Zhang Q, Yip GW, et al. Diastolic and systolic asynchrony in patients with diastolic heart failure: a common but ignored condition. J Am Coll Cardiol 2007; 49: 97–105.
  • 8
    Wang J, Kurrelmeyer KM, Torre-Amione G, Nagueh SF. Systolic and diastolic dyssynchrony in patients with diastolic heart failure and the effect of medical therapy. J Am Coll Cardiol 2007; 49: 88–96.
  • 9
    Perrone-Filardi P, Bacharach SL, Dilsizian V, Bonow RO. Effects of regional systolic asynchrony on left ventricular global diastolic function in patients with coronary artery disease. J Am Coll Cardiol 1992; 19: 739–744.
  • 10
    Achenbach S. Computed tomography coronary angiography. J Am Coll Cardiol 2006; 48: 1919–1928.
  • 11
    R.B. Devereux. Detection of left ventricular hypertrophy by M-mode echocardiography. Anatomic validation, standardization, and comparison to other methods. Hypertension 1987; 9: II19–26.
  • 12
    de Simone G, Daniels SR, Devereux RB, et al. Left ventricular mass and body size in normotensive children and adults: assessment of allometric relations and of the impact of overweight. J Am Coll Cardiol 1992; 20: 1251–1260.
  • 13
    Kjaergaard J, Hassager C, Oh JK, Kristensen JH, Berning J, Sogaard P. Measurement of cardiac time intervals by Doppler tissue M-mode imaging of the anterior mitral leaflet. J Am Soc Echocardiogr 2005; 18: 1058–1065.
  • 14
    Sohn DW, Chai IH, Lee DJ, et al. Assessment of mitral annulus velocity by Doppler tissue imaging in the evaluation of left ventricular diastolic function. J Am Coll Cardiol 1997; 30: 474–480.
  • 15
    Yu CM, Lin H, Yang H, Kong SL, Zhang Q, Lee SW. Progression of systolic abnormalities in patients with “isolated” diastolic heart failure and diastolic dysfunction. Circulation 2002; 105: 1195–1201.
  • 16
    Sohn DW, Chung WY, Chai IH, et al. Mitral annulus velocity in the noninvasive estimation of left ventricular peak dP/dt. Am J Cardiol 2001; 87: 933–936.
  • 17
    Pai RG, Gill KS. Amplitudes, durations, and timings of apically directed left ventricular myocardial velocities II. Systolic and diastolic asynchrony in patients with left ventricular hypertrophy. J Am Soc Echocardiogr 1998; 11: 112–118.
  • 18
    Marwick TH. Measurement of strain and strain rate by echocardiography: ready for prime time? J Am Coll Cardiol 2006; 47: 1313–1327.
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