• 1.
    Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics—2011 update: a report from the American Heart Association. Circulation. 2011;123:e18e209.
  • 2.
    Mehta RH, Rathore SS, Radford MJ, et al. Acute myocardial infarction in the elderly: differences by age. J Am Coll Cardiol. 2001;38:736741.
  • 3.
    Granger CB, Goldberg RJ, Dabbous O, et al; for the Global Registry of Acute Coronary Events Investigators. Predictors of hospital mortality in the Global Registry of Acute Coronary Events. Arch Intern Med. 2003;163:23452353.
  • 4.
    Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease. Circulation. 2003;107:346354.
  • 5.
    Shanmugasundaram M, Alpert JS. Acute coronary syndrome in the elderly. Clin Cardiol. 2009;32:608613.
  • 6.
    Alexander KP, Newby LK, Cannon CP, et al; for the American Heart Association Council on Clinical Cardiology; Society of Geriatric Cardiology. Acute coronary care in the elderly, part I: Non-ST-segment-elevation acute coronary syndromes: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology. Circulation. 2007;115:25492569.
  • 7.
    Thomas MP, Moscucci M, Smith DE, et al.; for the Blue Cross Blue Shield of Michigan Cardiovascular Consortium. Outcome of contemporary percutaneous coronary intervention in the elderly and the very elderly: insights from the Blue Cross Blue Shield of Michigan Cardiovascular Consortium. Clin Cardiol. 2011;34: 549554.
  • 8.
    Appleby CE, Ivanov J, Mackie K, et al. In-hospital outcomes of very elderly patients (85 years and older) undergoing percutaneous coronary intervention. Catheter Cardiovasc Interv. 2011;77: 634641.
  • 9.
    Sarzani R, Dessi-Fulgheri P, Paci VM, et al. Expression of natriuretic peptide receptors in human adipose and other tissues. J Endocrinol Invest. 1996;19:581585.
  • 10.
    Wallen T, Landahl S, Hedner T, et al. Brain natriuretic peptide in an elderly population. J Intern Med. 1997;242:307311.
  • 11.
    Redfield MM, Rodeheffer RJ, Jacobsen SJ, et al. Plasma brain natriuretic peptide concentration: impact of age and gender. J Am Coll Cardiol. 2002;40:976982.
  • 12.
    Coresh J, Selvin E, Stevens LA, et al. Prevalence of chronic kidney disease in the United States. JAMA. 2007;298:20382047.
  • 13.
    Vickery S, Price CP, John RI, et al. B-type natriuretic peptide (BNP) and aminoterminal proBNP in patients with CKD: relationship to renal function and left ventricular hypertrophy. Am J Kidney Dis. 2005;46:610620.
  • 14.
    Austin WJ, Bhalla V, Hernandez-Arce I, et al. Correlation and prognostic utility of Btype natriuretic peptide and its amino-terminal fragment in patients with chronic kidney disease. Am J Clin Pathol. 2006;126:506512.
  • 15.
    Wang TJ, Larson MG, Levy D, et al. Impact of obesity on plasma natriuretic peptide levels. Circulation. 2004;109:594600.
  • 16.
    Horwich TB, Hamilton MA, Fonarow GC. B-type natriuretic peptide levels in obese patients with advanced heart failure. J Am Coll Cardiol. 2006;47:8590.
  • 17.
    James SK, Lindahl B, Siegbahn A, et al. N-terminal pro-brain natriuretic peptide and other risk markers for the separate prediction of mortality and subsequent myocardial infarction in patients with unstable coronary artery disease: a Global Utilization of Strategies To Open occluded arteries (GUSTO)-IV substudy. Circulation. 2003;108:275281.
  • 18.
    Das SR, Drazner MH, Dries DL, et al. Impact of body mass and body composition on circulating levels of natriuretic peptides: results from the Dallas Heart Study. Circulation. 2005;112: 21632168.
  • 19.
    Chang AY, Abdullah SM, Jain T, et al. Associations among androgens, estrogens, and natriuretic peptides in young women: observations from the Dallas Heart Study. J Am Coll Cardiol. 2007 2;49: 109116.
  • 20.
    Steensma DP, Tefferi A. Anemia in the elderly: how should we define it, when does it matter, and what can be done? Mayo Clin Proc. 2007;82:958966.
  • 21.
    Fukuta H, Ohte N, Mukai S, et al. Anemia is an independent predictor for elevated plasma levels of natriuretic peptides in patients undergoing cardiac catheterization for coronary artery disease. Circ J. 2008;72:212217.
  • 22.
    Nybo M, Benn M, Mogelvang R, et al. Impact of hemoglobin on plasma pro-B-type natriuretic peptide concentrations in the general population. Clin Chem. 2007;53:19211927.
  • 23.
    Desai AS, Bibbins-Domingo K, Shlipak MG, et al. Association between anemia and N-terminal pro-B-type natriuretic peptide (NT-proBNP): findings from the Heart and Soul Study. Eur J Heart Fail. 2007;9:886891.
  • 24.
    Wallen T, Landahl S, Hedner T, et al. Brain natriuretic peptide predicts mortality in the elderly. Heart. 1997;77:264267.
  • 25.
    Daniels LB, Laughlin GA, Clopton P, et al. Minimally elevated cardiac troponin T and elevated N-terminal pro-B-type natriuretic peptide predict mortality in older adults: results from the Rancho Bernardo Study. J Am Coll Cardiol. 2008;52:450459.
  • 26.
    Kistorp C, et al. N-terminal pro-brain natriuretic peptide, C-reactive protein, and urinary albumin levels as predictors of mortality and cardiovascular events in older adults. JAMA. 2005;293: 16091616.
  • 27.
    de Lemos JA, Morrow DA, Bentley JH, et al. The prognostic value of B-type natriuretic peptide in patients with acute coronary syndromes. N Engl J Med. 2001;345:10141021.
  • 28.
    Mega JL, Morrow DA, de Lemos JA, et al. B-type natriuretic peptide at presentation and prognosis in patients with ST-segment elevation myocardial infarction: an ENTIRETIMI-23 substudy. J Am Coll Cardiol. 2004;44:335339.
  • 29.
    Omland T, Persson A, Ng L, et al. N-terminal pro-B-type natriuretic peptide and longterm mortality in acute coronary syndromes. Circulation. 2002;106:29132918.
  • 30.
    Drewniak W, Snopek G, Zarukiewicz M, et al. Prognostic value of the N-terminal pro-B-type natriuretic peptide in the elderly with acute myocardial infarction. Kardiol Pol. 2008;66:750755.
  • 31.
    Lorgis L, Zeller M, Dentan G, et al; RICO Survey Working Group. Prognostic value of N-terminal probrain natriuretic peptide in elderly people with acute myocardial infarction: prospective observational study. BMJ. 2009;338:b1605.