Doxorubicin-induced cardiomyopathy treated with carvedilol
Article first published online: 3 FEB 2009
Copyright © 1998 Wiley Periodicals, Inc.
Volume 21, Issue 10, pages 777–779, September 1998
How to Cite
Fazio, S., Palmieri, E. A., Ferravante, B., Bon È, F. and Biondi, B. (1998), Doxorubicin-induced cardiomyopathy treated with carvedilol. Clin Cardiol, 21: 777–779. doi: 10.1002/clc.4960211017
- Issue published online: 3 FEB 2009
- Article first published online: 3 FEB 2009
- Manuscript Accepted: 21 MAY 1998
- Manuscript Received: 12 DEC 1997
Even today, heart failure due to doxorubicin-induced dilated cardiomyopathy seems to have a poor prognosis, as it is often irreversible and relatively unresponsive to standard medical treatment. This paper describes the first case of a patient complaining of severe symptoms of congestive heart failure due to doxorubicin-induced dilated cardiomyopathy unresponsive to standard medical treatment (digoxin, diuretics, and angiotensin-converting enzyme inhibitor), who showed complete clinical recovery and significant improvement of left ventricular dysfunction after carvedilol treatment. It also illustrates the possibility that carvedilol may be a first-choice drug for the treatment of this disease.