Consultant and receives research support from Dade-Behring, Beckman-Couler, and Roche. He is or has been at one time a consultant for most of the companies who make troponin assays.
Elevations of troponin in patients with epileptic seizures? What do they mean?
Article first published online: 5 DEC 2006
Copyright © 2006 Verlag Chemie, GmbH
Volume 29, Issue 7, pages 325–326, July 2006
How to Cite
Parvulescu-Codrea, S., Britton, J. W., Bruce, C. J., Cascino, G. D. and Jaffe, A. S. (2006), Elevations of troponin in patients with epileptic seizures? What do they mean?. Clin Cardiol, 29: 325–326. doi: 10.1002/clc.4960290713
- Issue published online: 5 DEC 2006
- Article first published online: 5 DEC 2006
- Manuscript Accepted: 24 MAR 2006
- Manuscript Received: 14 FEB 2006
- medical emergencies;
- myocardial infarction;
- pulmonary emboli
Cardiac troponin concentrations are important sensitive and specific markers for myocardial injury in clinical medicine. Troponin (TnT) elevations have been noted in some series in the setting of acute neurologic disease. We have previously reported that solitary seizures do not evoke elevations in TnT. The importance of this negative finding is exemplified by a patient who arrived at our clinic following a new onset seizure and in whom the cardiac TnT level was observed to rise. Triggered by this observation and by the knowledge that seizures alone would not do this, a subsequent targeted cardiologic workup documented what was believed to be an extension of a previously unrecognized myocardial infarction, with a seizure as its clinical presentation. Elevations of troponin should not be considered to be due to isolated seizures. This case illustrates the importance of having data concerning the response of troponin in various emergency and clinical situations.