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New issues in the pathogenesis of hepatocellular carcinoma: Applying insights from next-generation DNA sequencing technologies to improve therapy for hepatocellular carcinoma†
Article first published online: 23 JAN 2013
DOI: 10.1002/cld.113
Copyright © 2012 the American Association for the Study of Liver Diseases
Issue
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Clinical Liver Disease
Special Issue: Current Issues in Hepatocellular Carcinoma
Volume 1, Issue 6, pages 200–205, December 2012
Additional Information
How to Cite
Chaiteerakij, R. and Roberts, L. R. (2012), New issues in the pathogenesis of hepatocellular carcinoma: Applying insights from next-generation DNA sequencing technologies to improve therapy for hepatocellular carcinoma. Clinical Liver Disease, 1: 200–205. doi: 10.1002/cld.113
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Publication History
- Issue published online: 23 JAN 2013
- Article first published online: 23 JAN 2013
- Manuscript Accepted: 16 OCT 2012
- Manuscript Received: 6 SEP 2012
REFERENCES
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- 3, , , , , , et al. Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A 2011; 108: 12042–12047.
- 4, , , , , , et al. Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators. Nat Genet 2012; 44: 760–764.
- 5, , , , , , et al. Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet 2012; 44: 694–698.
- 6, , , , , , et al. Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma. Nat Genet 2012; 44: 1117–1121.
- 7, , , , , , et al. Integration of the hepatitis B virus (HBV) and human papilloma virus (HPV) into the human telomerase reverse transcriptase (hTERT) gene in liver and cervical cancers. Oncogene 2003; 22: 3813–3820.
- 8, , , , , , et al. Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene. Oncogene 2003; 22: 3911–3916.

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