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Emerging molecular mechanisms that power and regulate the anastral mitotic spindle of flowering plants
Article first published online: 29 OCT 2007
DOI: 10.1002/cm.20247
Copyright © 2007 Wiley-Liss, Inc.
Additional Information
How to Cite
Bannigan, A., Lizotte-Waniewski, M., Riley, M. and Baskin, T. I. (2008), Emerging molecular mechanisms that power and regulate the anastral mitotic spindle of flowering plants. Cell Motil. Cytoskeleton, 65: 1–11. doi: 10.1002/cm.20247
Publication History
- Issue published online: 17 DEC 2007
- Article first published online: 29 OCT 2007
- Manuscript Accepted: 26 SEP 2007
- Manuscript Received: 18 JUL 2007
Funded by
- U.S. Department of Energy. Grant Number: DE-FG02-03ER15421
REFERENCES
- ,,,,. 1990. Basic local alignment search tool. J Mol Biol 215: 403–410.
- ,. 2007. The kinesin ATK5 functions in early spindle assembly in Arabidopsis. Plant Cell 19: 226–236.
- ,. Mitotic spindle assembly and function. In: VermaDPS,HongZ, editors. Cell Division Control in Plants. Berlin: Springer, in press.
- ,,,,. 2005. A minus-end-directed kinesin with plus-end tracking protein activity is involved in spindle morphogenesis. Mol Biol Cell 16: 1584–1592.
- . 1999. The spindle checkpoint. Curr Opin Genet Dev 9: 69–75.
- ,,. 1997. TKRP125, a kinesin-related protein involved in the centrosome-independent organization of the cytokinetic apparatus in tobacco BY-2 cells. J Cell Sci 110: 179–189.
- ,. 1986. Reorganization of microtubules in endosperm cells and cell fragments of the higher plant Haemanthus in vivo J Cell Biol 102: 263–281.
- ,,,,,,. 2007. A conserved role for kinesin-5 in plant mitosis. J Cell Sci 120: 2819–2827.
- ,,,,,. 2000.Two kinesin-related proteins associated with the cold-stable cytoskeleton of carrot cells: Characterization of a novel kinesin. DcKRP120-2.Plant J 24: 859–868.
- ,. 1990. The structure and function of the mitotic spindle in flowering plants. Annu Rev Plant Physiol Plant Mol Biol 41: 277–315.
- ,,,,,. 1998. Treatment of Vicia faba root tip cells with specific inhibitors to cyclin-dependent kinases leads to abnormal spindle formation. Plant J 16: 697–707.Direct Link:
- ,,,,,,. 2006. γ-Tubulin is essential for acentrosomal microtubule nucleation and coordination of late mitotic events in Arabidopsis. Plant Cell 18: 1199–1212.
- ,,,,,. 1995. Phosphorylation by per regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell 83: 1159–1169.
- ,,,. 2005. Localization of the microtubule end binding protein EB1 reveals alternative pathways of spindle development in Arabidopsis suspension cells. Plant Cell 17: 1737–1748.
- ,,,,,,,. 2002. The Arabidopsis ATK1 gene is required for spindle morphogenesis in male meiosis. Development 129: 2401–2409.
- . 2000. Spindle assembly in animal cells. Annu Rev Biochem 69: 95–114.
- ,. 2004. A new kinesin tree. J Cell Sci. 117: 3–7.
- ,,,. 2005. Microtubule plus-ends reveal essential links between intracellular polarization and localized modulation of endocytosis during division-plane establishment in plant cells. BMC Biol 3: 11.
- ,,. 2006. Contribution of microtubule growth polarity and flux to spindle assembly and functioning in plant cells. J Cell Sci 119: 3193–3205.
- ,,,,,. 2003. Plant γ-tubulin interacts with αβ-tubulin dimers and forms membrane-associated complexes. Plant Cell 15: 465–480.
- . 1999. Microtubule motors in spindle and chromosome motility. Eur J Biochem 262: 12–17.Direct Link:
- ,. 2004. Mechanisms and molecules of the mitotic spindle. Curr Biol 14: R797–R805.
- ,. 1999. The road less traveled: Emerging principles of kinesin motor utilization. Annu Rev Cell Dev Biol 15: 141–183.
- ,. 2003. The roles of microtubule-based motor proteins in mitosis: Comprehensive RNAi analysis in the Drosophila S2 cell line. J Cell Biol 162: 1003–1016.
- ,. 2001. Use of abnormal preprophase bands to decipher division plane determination. J Cell Sci 114: 599–607.
- ,. 1990. Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene. Nature 347: 563–566.
- . 2007. Microtubule-associated proteins in higher plants. J Plant Res 120: 79–98.
- ,. 1992. The Drosophila ncd microtubule motor protein is spindle-associated in meiotic and mitotic cells. J Cell Sci 103: 1013–1020.
- ,,,,,,. 1996. Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts. Nature 382: 420–425.
- ,,,,,. 1993. The kinesin-like protein KLP61F is essential for mitosis in Drosophila. J Cell Biol 123: 665–679.
- ,,,. 1999. Lethal level overexpression of γ-tubulin in fission yeast causes mitotic arrest. Cell Motil Cytoskel 44: 284–295.Direct Link:
- ,. 2007. Microtubule polymerases and depolymerases. Curr Opin Cell Biol 19: 31–35.
- ,,,,,. 2005. The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks. Nature 435: 114–118.
- ,,,. 2000. Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. J Cell Biol 150: 975–988.
- ,. 2001. The mitotic spindle: A self-made machine. Science 294: 543–547.
- ,,,,,,. 2006. MICROTUBULE ORGANIZATION 1 regulates structure and function of microtubule arrays during mitosis and cytokinesis in the Arabidopsis root. Plant Physiol 140: 102–114.
- ,,,. 2002. Maximum likelihood methods reveal conservation of function among closely related kinesin families. J Mol Evol 54: 42–53.
- ,,,,,,,,,,,,,,,,,,,,,. 2004. A standardized kinesin nomenclature. J Cell Biol 167: 19–22.
- ,. 2004. Cytoskeletal motors in Arabidopsis. Sixty-one kinesins and seventeen myosins. Plant Physiol 136: 3877–3883.
- ,,,,,. 1994. γ-Tubulin in Arabidopsis: Gene sequence, immunoblot, and immunofluorescence studies. Plant Cell 6: 303–314.
- ,. 2006. Not so divided: The common basis of plant and animal cell division. Nat Rev Mol Cell Biol 7: 147–152.
- ,,. 1996. Cytokinesis in the Arabidopsis embryo involves the syntaxin-related KNOLLE gene product. Cell 84: 61–71.
- ,,,,. 2005. Modulated targeting of GFP-AtMAP65-1 to central spindle microtubules during division. Plant J 43: 469–478.Direct Link:
- ,,,. 2003. A kinesin mutant with an atypical bipolar spindle undergoes normal mitosis. Mol Biol Cell 14: 1717–1726.
- ,,,. 1996. Anastral meiotic spindle morphogenesis: Role of the non-claret disjunctional kinesin-like protein. J Cell Biol 134: 455–464.
- . 1984. Centrosomes and mitotic poles. Exp Cell Res 153: 1–15.
- ,. 1995. Chromosomal control of meiotic cell division. Science 270: 1595–1601.
- ,. 2002. Fission yeast Mad3p is required for Mad2p to inhibit the anaphase-promoting complex and localizes to kinetochores in a Bub1p-, Bub3p-, and Mph1p-dependent manner. Mol Cell Biol 22: 2728–2742.
- . 1999. The preprophase band of microtubules: Its function as a cytokinetic apparatus in higher plants. Int Rev Cytol 187: 1–49.
- ,,,,,. 2002. Two new loci, PLEIADE and HYADE, implicate organ-specific regulation of cytokinesis in Arabidopsis. Plant Physiol 130: 312–324.
- ,,,,,,,. 2005. Microtubule-dependent microtubule nucleation based on recruitment of γ-tubulin in higher plants. Nat Cell Biol 7: 961–968.
- ,,,,,. 2007. Discrete states of a protein interaction network govern interphase and mitotic microtubule dynamics. PLoS Biol 5: e29.
- ,,,. 1993. Suppression of the BIMC4 mitotic spindle defect by deletion of klpA, a gene encoding a KAR3-related kinesin-like protein in Aspergillus nidulans. J Cell Biol 120: 153–162.
- ,. 2000. Cytokinesis in flowering plants: More than one way to divide a cell. Curr Opin Plant Biol 3: 493–502.
- ,,. 2006. Cytoskeletal asymmetry in Zea mays subsidiary cell mother cells: A monopolar prophase microtubule half-spindle anchors the nucleus to its polar position. Cell Motil Cytoskeleton 63: 696–709.Direct Link:
- ,,,,,,,,. 2006. γ-Tubulin is essential for microtubule organization and development in Arabidopsis. Plant Cell 8: 1412–1425.
- ,. 2006. Kinesin-5 motors are required for organization of spindle microtubules in Silvetia compressa zygotes. BMC Plant Biol 6: 19–28.
- ,. 2005. The spindle checkpoint: Tension versus attachment. Trends Cell Biol 15: 486–493.
- ,. 2001. Kinesin in the Arabidopsis genome: A comparative analysis among eukaryotes. BMC Genomics 2: 2–14.
- ,,. 2006. Comprehensive comparative analysis of kinesins in photosynthetic eukaryotes. BMC Genomics 7: 18.
- ,. 1992. Kinesin-related proteins required for structural integrity of the mitotic spindle. Cell 70: 451–458.
- ,. 1995. Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle. Proc Natl Acad Sci USA 92: 4289–4293.
- ,,,. 1992. Mitotic spindle organization by a plus-end-directed microtubule motor. Nature 359: 540–543.
- ,,,,,,,. 1999. The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles. J Cell Biol 144: 125–138.
- ,,,,,. 2000a. Functional coordination of three mitotic motors in Drosophila embryos. Mol Biol Cell 11: 241–253.
- ,,. 2000b. Microtubule motors in mitosis. Nature 407: 41–47.
- ,,,,,,. 2006. Control of the AtMAP65-1 interaction with microtubules through the cell cycle. J Cell Sci 119: 3227–3237.
- ,,,,,. 2002. Cytokinesis-defective mutants of Arabidopsis. Plant Physiol 129: 678–690.
- ,,,,. 1986. Aster-free spindle poles in insect spermatocytes: Evidence for chromosome-induced spindle formation? J Cell Biol 102: 1679–1687.
- ,,,,,,. 2002. The Arabidopsis HINKEL gene encodes a kinesin-related protein involved in cytokinesis and is expressed in a cell cycle-dependent manner. Curr Biol 12: 153–158.
- . 2002. PAUP: Phylogenetic analysis using parsimony version4b10. Sunderland, MA: Sinauer Associates.
- ,,. 1994. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 22: 4673–4680.
- ,,. 2001. Boursin, a sea urchin bimC kinesin protein, plays a role in anaphase and cytokinesis. J Cell Sci 114: 481–491.
- ,,,,,. 2006. Mitosis-specific kinesins in Arabidopsis. Trends Plant Sci 11: 167–175.
- . 2004. Functional role of centrosomes in spindle assembly and organization. J Cell Biochem 91: 904–914.Direct Link:
- ,. 2004. E pluribus unum: Towards a universal mechanism for spindle assembly. Trends Cell Biol 14: 413–414.
- ,,,,,,,. 2001. Dynamic recruitment of Cdc2 to specific microtubule structures during mitosis. Plant Cell 13: 1929–1943.
- ,,,,,. 2002. Mutant alleles of Arabidopsis RADIALLY SWOLLEN4 and 7 reduce growth anisotropy without altering the transverse orientation of cortical microtubules or cellulose microfibrils. Development 129: 4821–4830.
- ,. 2006. Microtubule nucleation: γ-Tubulin and beyond. J Cell Sci 119: 4143–4153.
- ,,,,. 2002. Stu1p is physically associated with β-tubulin and is required for structural integrity of the mitotic spindle. Mol Biol Cell 13: 1881–1892.
- ,,,,. 2005. Decision of spindle poles and division plane by double preprophase bands in a BY-2 cell line expressing GFP-tubulin. Plant Cell Physiol 46: 531–538.
- ,,. 1999. The maize homologue of the cell cycle checkpoint protein MAD2 reveals kinetochore substructure and contrasting mitotic and meiotic localization patterns. J Cell Biol 145: 425–435.
- ,,,. 1995. Nucleation of microtubule assembly by a γ-tubulin-containing ring complex. Nature 378: 578–583.