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  • Aijaz S, D'Atri F, Citi S, Balda MS, Matter K. 2005. Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition. Dev Cell 8( 5): 777786.
  • Balda MS, Matter K. 2008. Tight junctions at a glance. J Cell Sci 121 ( Part 22): 36773682.
  • Balda MS, Flores-Maldonado C, Cereijido M, Matter K. 2000. Multiple domains of occludin are involved in the regulation of paracellular permeability. J Cell Biochem 78( 1): 8596.
  • Ballard ST, Hunter JH, Taylor AE. 1995. Regulation of tight-junction permeability during nutrient absorption across the intestinal epithelium. Annu Rev Nutr 15: 3555.
  • Bazzoni G, Martinez-Estrada OM, Orsenigo F, Cordenonsi M, Citi S, Dejana E. 2000. Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin. J Biol Chem 275( 27): 2052020526.
  • Benais-Pont G, Punn A, Flores-Maldonado C, Eckert J, Raposo G, Fleming TP, Cereijido M, Balda MS, Matter K. 2003. Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability. J Cell Biol 160( 5): 729740.
  • Bentzel CJ, Hainau B, Edelman A, Anagnostopoulos T, Benedetti EL. 1976. Effect of plant cytokinins on microfilaments and tight junction permeability. Nature 264( 5587): 666668.
  • Bentzel CJ, Hainau B, Ho S, Hui SW, Edelman A, Anagnostopoulos T, Benedetti EL. 1980. Cytoplasmic regulation of tight-junction permeability: effect of plant cytokinins. Am J Physiol 239( 3): C75C89.
  • Berkes J, Viswanathan VK, Savkovic SD, Hecht G. 2003. Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation. Gut 52( 3): 439451.
  • Bruewer M, Hopkins AM, Hobert ME, Nusrat A, Madara JL. 2004. RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin. Am J Physiol Cell Physiol 287( 2): C327C335.
  • Chen VC, Li X, Perreault H, Nagy JI. 2006. Interaction of zonula occludens-1 (ZO-1) with alpha-actinin-4: application of functional proteomics for identification of PDZ domain-associated proteins. J Proteome Res 5( 9): 21232134.
  • Citi S, Sabanay H, Jakes R, Geiger B, Kendrick-Jones J. 1988. Cingulin, a new peripheral component of tight junctions. Nature 333( 6170): 272276.
  • Citi S, Paschoud S, Pulimeno P, Timolati F, De Robertis F, Jond L, Guillemot L. 2009. The tight junction protein cingulin regulates gene expression and RhoA signaling. Ann NY Acad Sci 1165: 8898.
  • Colegio OR, Van Itallie CM, McCrea HJ, Rahner C, Anderson JM. 2002. Claudins create charge-selective channels in the paracellular pathway between epithelial cells. Am J Physiol Cell Physiol 283( 1): C142C147.
  • Cordenonsi M, D'Atri F, Hammar E, Parry DA, Kendrick-Jones J, Shore D, Citi S. 1999. Cingulin contains globular and coiled-coil domains and interacts with ZO-1, ZO-2, ZO-3, and myosin. J Cell Biol 147( 7): 15691582.
  • D'Atri F, Citi S. 2001. Cingulin interacts with F-actin in vitro. FEBS Lett 507( 1): 2124.
  • Denker BM, Sabath E. 2011. The biology of epithelial cell tight junctions in the kidney. J Am Soc Nephrol 22( 4): 622625.
  • Drenckhahn D, Dermietzel R. 1988. Organization of the actin filament cytoskeleton in the intestinal brush border: a quantitative and qualitative immunoelectron microscope study. J Cell Biol 107( 3): 10371048.
  • Elia C, Bucca C, Rolla G, Scappaticci E, Cantino D. 1988. A freeze-fracture study of human bronchial epithelium in normal, bronchitic and asthmatic subjects. J Submicrosc Cytol Pathol 20( 3): 509517.
  • Etournay R, Zwaenepoel I, Perfettini I, Legrain P, Petit C, El-Amraoui A. 2007. Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions. J Cell Sci 120( Pt 16): 28382850.
  • Fanning AS. 2001. Organization and regulation of the tight junction by the actin-myosin cytoskeleton. In: Cereijido M, Anderson JM, editors. Tight Junctions. 2 ed. Boca Raton: CRC Press LLC. pp 265284.
  • Fanning AS, Anderson JM. 2009. Zonula occludens-1 and −2 are cytosolic scaffolds that regulate the assembly of cellular junctions. Ann NY Acad Sci 1165: 113120.
  • Fanning AS, Jameson BJ, Jesaitis LA, Anderson JM. 1998. The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J Biol Chem 273( 45): 2974529753.
  • Feighery LM, Cochrane SW, Quinn T, Baird AW, O'Toole D, Owens SE, O'Donoghue D, Mrsny RJ, Brayden DJ. 2008. Myosin light chain kinase inhibition: correction of increased intestinal epithelial permeability in vitro. Pharm Res 25( 6): 13771386.
  • Fine KD, Santa Ana CA, Porter JL, Fordtran JS. 1993. Effect of D-glucose on intestinal permeability and its passive absorption in human small intestine in vivo. Gastroenterology 105( 4): 11171125.
  • Furuse M. 2010. Molecular basis of the core structure of tight junctions. Cold Spring Harb Perspect Biol 2( 1): a002907.
  • Furuse M, Hirase T, Itoh M, Nagafuchi A, Yonemura S, Tsukita S. 1993. Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol 123( 6 Pt 2): 17771788.
  • Furuse M, Itoh M, Hirase T, Nagafuchi A, Yonemura S, Tsukita S. 1994. Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J Cell Biol 127( 6 Pt 1): 16171626.
  • Furuse M, Fujita K, Hiiragi T, Fujimoto K, Tsukita S. 1998a. Claudin-1 and −2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 141( 7): 15391550.
  • Furuse M, Sasaki H, Fujimoto K, Tsukita S. 1998b. A single gene product, claudin-1 or −2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J Cell Biol 143( 2): 391401.
  • Goldblum SE, Rai U, Tripathi A, Thakar M, De Leo L, Di Toro N, Not T, Ramachandran R, Puche AC, Hollenberg MD, et al. 2011. The active Zot domain (aa 288-293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation. FASEB J 25( 1): 144158.
  • Guillemot L, Citi S. 2006. Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA. Mol Biol Cell 17( 8): 35693577.
  • Guillemot L, Hammar E, Kaister C, Ritz J, Caille D, Jond L, Bauer C, Meda P, Citi S. 2004. Disruption of the cingulin gene does not prevent tight junction formation but alters gene expression. J Cell Sci 117 ( Part 22): 52455256.
  • Hartsock A, Nelson WJ. 2008. Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim Biophys Acta 1778( 3): 660669.
  • Hecht G, Pestic L, Nikcevic G, Koutsouris A, Tripuraneni J, Lorimer DD, Nowak G, Guerriero V, Jr., Elson EL, Lanerolle PD. 1996. Expression of the catalytic domain of myosin light chain kinase increases paracellular permeability. Am J Physiol 271( 5 Part 1): C1678C1684.
  • Hirokawa N, Tilney LG. 1982. Interactions between actin filaments and between actin filaments and membranes in quick-frozen and deeply etched hair cells of the chick ear. J Cell Biol 95( 1): 249261.
  • Hirokawa N, Keller TC, III, Chasan R, Mooseker MS. 1983. Mechanism of brush border contractility studied by the quick-freeze, deep-etch method. J Cell Biol 96( 5): 13251336.
  • Holgate ST. 2007. Epithelium dysfunction in asthma. J Allergy Clin Immunol 120( 6): 12331244; quiz 1245–1246.
  • Hollander D. 1999. Intestinal permeability, leaky gut, and intestinal disorders. Curr Gastroenterol Rep 1( 5): 410416.
  • Huo L, Wen W, Wang R, Kam C, Xia J, Feng W, Zhang M. 2011. Cdc42-dependent formation of the ZO-1/MRCKbeta complex at the leading edge controls cell migration. EMBO J 30( 4): 665678.
  • Ikenouchi J, Umeda K, Tsukita S, Furuse M. 2007. Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization. J Cell Biol 176( 6): 779786.
  • Itoh M, Nagafuchi A, Moroi S, Tsukita S. 1997. Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J Cell Biol 138( 1): 181192.
  • Itoh M, Furuse M, Morita K, Kubota K, Saitou M, Tsukita S. 1999. Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol 147( 6): 13511363.
  • Ivanov AI, McCall IC, Parkos CA, Nusrat A. 2004. Role for actin filament turnover and a myosin II motor in cytoskeleton-driven disassembly of the epithelial apical junctional complex. Mol Biol Cell 15( 6): 26392651.
  • Ivanov AI, Hunt D, Utech M, Nusrat A, Parkos CA. 2005. Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex. Mol Biol Cell 16( 6): 26362650.
  • Ivanov AI, McCall IC, Babbin B, Samarin SN, Nusrat A, Parkos CA. 2006. Microtubules regulate disassembly of epithelial apical junctions. BMC Cell Biol 7: 12.
  • Ivanov AI, Bachar M, Babbin BA, Adelstein RS, Nusrat A, Parkos CA. 2007. A unique role for nonmuscle myosin heavy chain IIA in regulation of epithelial apical junctions. PLoS One 2( 7): e658.
  • Ivanov AI, Parkos CA, Nusrat A. 2010. Cytoskeletal regulation of epithelial barrier function during inflammation. Am J Pathol 177( 2): 512524.
  • John LJ, Fromm M, Schulzke JD. 2011. Epithelial barriers in intestinal inflammation. Antioxid Redox Signal 15( 5): 12551270.
  • Jou TS, Schneeberger EE, Nelson WJ. 1998. Structural and functional regulation of tight junctions by RhoA and Rac1 small GTPases. J Cell Biol 142( 1): 101115.
  • Kremerskothen J, Stolting M, Wiesner C, Korb-Pap A, van Vliet V, Linder S, Huber TB, Rottiers P, Reuzeau E, Genot E, et al. 2011. Zona occludens proteins modulate podosome formation and function. FASEB J 25( 2): 505514.
  • Ma TY, Hollander D, Tran LT, Nguyen D, Hoa N, Bhalla D. 1995. Cytoskeletal regulation of Caco-2 intestinal monolayer paracellular permeability. J Cell Physiol 164( 3): 533545.
  • Madara JL. 1987. Intestinal absorptive cell tight junctions are linked to cytoskeleton. Am J Physiol 253( 1 Part 1): C171C175.
  • Madara JL, Pappenheimer JR. 1987. Structural basis for physiological regulation of paracellular pathways in intestinal epithelia. J Membr Biol 100( 2): 149164.
  • Madara JL, Barenberg D, Carlson S. 1986. Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity. J Cell Biol 102( 6): 21252136.
  • Madara JL, Moore R, Carlson S. 1987. Alteration of intestinal tight junction structure and permeability by cytoskeletal contraction. Am J Physiol 253( 6 Part 1): C854C861.
  • Madara JL, Stafford J, Barenberg D, Carlson S. 1988. Functional coupling of tight junctions and microfilaments in T84 monolayers. Am J Physiol 254( 3 Part 1): G416G423.
  • Marchiando AM, Shen L, Graham WV, Weber CR, Schwarz BT, Austin JR, II, Raleigh DR, Guan Y, Watson AJ, Montrose MH, et al. 2010. Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. J Cell Biol 189( 1): 111126.
  • Martin-Padura I, Lostaglio S, Schneemann M, Williams L, Romano M, Fruscella P, Panzeri C, Stoppacciaro A, Ruco L, Villa A, et al. 1998. Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol 142( 1): 117127.
  • Mattagajasingh SN, Huang SC, Hartenstein JS, Benz EJ, Jr. 2000. Characterization of the interaction between protein 4.1R and ZO-2. A possible link between the tight junction and the actin cytoskeleton. J Biol Chem 275( 39): 3057330585.
  • Meza I, Ibarra G, Sabanero M, Martinez-Palomo A, Cereijido M. 1980. Occluding junctions and cytoskeletal components in a cultured transporting epithelium. J Cell Biol 87( 3 Part 1): 746754.
  • Morita K, Furuse M, Fujimoto K, Tsukita S. 1999. Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc Natl Acad Sci USA 96( 2): 511516.
  • Nagumo Y, Han J, Bellila A, Isoda H, Tanaka T. 2008. Cofilin mediates tight-junction opening by redistributing actin and tight-junction proteins. Biochem Biophys Res Commun 377( 3): 921925.
  • Nusrat A, Giry M, Turner JR, Colgan SP, Parkos CA, Carnes D, Lemichez E, Boquet P, Madara JL. 1995. Rho protein regulates tight junctions and perijunctional actin organization in polarized epithelia. Proc Natl Acad Sci USA 92( 23): 1062910633.
  • Ooshio T, Kobayashi R, Ikeda W, Miyata M, Fukumoto Y, Matsuzawa N, Ogita H, Takai Y. 2010. Involvement of the interaction of afadin with ZO-1 in the formation of tight junctions in Madin-Darby canine kidney cells. J Biol Chem 285( 7): 50035012.
  • Otani T, Ichii T, Aono S, Takeichi M. 2006. Cdc42 GEF Tuba regulates the junctional configuration of simple epithelial cells. J Cell Biol 175( 1): 135146.
  • Pappenheimer JR. 1987. Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters. J Membr Biol 100( 2): 137148.
  • Pappenheimer JR, Reiss KZ. 1987. Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat. J Membr Biol 100( 2): 123136.
  • Pulimeno P, Paschoud S, Citi S. 2011. A role for ZO-1 and PLEKHA7 in recruiting paracingulin to tight and adherens junctions of epithelial cells. J Biol Chem 286( 19): 1674316750.
  • Sasaki H, Matsui C, Furuse K, Mimori-Kiyosue Y, Furuse M, Tsukita S. 2003. Dynamic behavior of paired claudin strands within apposing plasma membranes. Proc Natl Acad Sci USA 100( 7): 39713976.
  • Severson EA, Parkos CA. 2009. Structural determinants of junctional adhesion molecule A (JAM-A) function and mechanisms of intracellular signaling. Curr Opin Cell Biol 21( 5): 701707.
  • Shen L, Turner JR. 2005. Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosis. Mol Biol Cell 16( 9): 39193936.
  • Shen L, Black ED, Witkowski ED, Lencer WI, Guerriero V, Schneeberger EE, Turner JR. 2006. Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. J Cell Sci 119 ( Part 10): 20952106.
  • Shen L, Su L, Turner JR. 2009. Mechanisms and functional implications of intestinal barrier defects. Dig Dis 27( 4): 443449.
  • Shen L, Weber CR, Raleigh DR, Yu D, Turner JR. 2011. Tight junction pore and leak pathways: a dynamic duo. Annu Rev Physiol 73: 283309.
  • Stevenson BR, Begg DA. 1994. Concentration-dependent effects of cytochalasin D on tight junctions and actin filaments in MDCK epithelial cells. J Cell Sci 107 ( Part 3): 367375.
  • Terry SJ, Zihni C, Elbediwy A, Vitiello E, Leefa Chong San IV, Balda MS, Matter K. 2011. Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis. Nat Cell Biol 13( 2): 159166.
  • Tsukita S, Furuse M, Itoh M. 2001. Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol 2( 4): 285293.
  • Turner JR, Rill BK, Carlson SL, Carnes D, Kerner R, Mrsny RJ, Madara JL. 1997. Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation. Am J Physiol 273( 4 Part 1): C1378C1385.
  • Turner JR, Angle JM, Black ED, Joyal JL, Sacks DB, Madara JL. 1999. PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase. Am J Physiol 277( 3 Part 1): C554C562.
  • Umeda K, Ikenouchi J, Katahira-Tayama S, Furuse K, Sasaki H, Nakayama M, Matsui T, Tsukita S, Furuse M. 2006. ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation. Cell 126( 4): 741754.
  • Utech M, Ivanov AI, Samarin SN, Bruewer M, Turner JR, Mrsny RJ, Parkos CA, Nusrat A. 2005. Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane. Mol Biol Cell 16( 10): 50405052.
  • Van Itallie CM, Anderson JM. 2004. The molecular physiology of tight junction pores. Physiology (Bethesda) 19: 331338.
  • Van Itallie CM, Anderson JM. 2011. Measuring size-dependent permeability of the tight junction using PEG profiling. Methods Mol Biol 762: 111.
  • Van Itallie CM, Holmes J, Bridges A, Gookin JL, Coccaro MR, Proctor W, Colegio OR, Anderson JM. 2008. The density of small tight junction pores varies among cell types and is increased by expression of claudin-2. J Cell Sci 121 ( Part 3): 298305.
  • Van Itallie CM, Fanning AS, Bridges A, Anderson JM. 2009. ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton. Mol Biol Cell 20( 17): 39303940.
  • Walsh SV, Hopkins AM, Chen J, Narumiya S, Parkos CA, Nusrat A. 2001. Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia. Gastroenterology 121( 3): 566579.
  • Wittchen ES, Haskins J, Stevenson BR. 1999. Protein interactions at the tight junction. Actin has multiple binding partners, and ZO-1 forms independent complexes with ZO-2 and ZO-3. J Biol Chem 274( 49): 3517935185.
  • Wittchen ES, Haskins J, Stevenson BR. 2003. NZO-3 expression causes global changes to actin cytoskeleton in Madin-Darby canine kidney cells: linking a tight junction protein to Rho GTPases. Mol Biol Cell 14( 5): 17571768.
  • Yamazaki Y, Umeda K, Wada M, Nada S, Okada M, Tsukita S. 2008. ZO-1- and ZO-2-dependent integration of myosin-2 to epithelial zonula adherens. Mol Biol Cell 19( 9): 38013811.
  • Yu D, Marchiando AM, Weber CR, Raleigh DR, Wang Y, Shen L, Turner JR. 2010. MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier function. Proc Natl Acad Sci USA 107( 18): 82378241.
  • Zeissig S, Burgel N, Gunzel D, Richter J, Mankertz J, Wahnschaffe U, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD. 2007. Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease. Gut 56( 1): 6172.
  • Zolotarevsky Y, Hecht G, Koutsouris A, Gonzalez DE, Quan C, Tom J, Mrsny RJ, Turner JR. 2002. A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. Gastroenterology 123( 1): 163172.