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Investigation of D1 Receptor–Agonist Interactions and D1/D2 Agonist Selectivity Using a Combination of Pharmacophore and Receptor Homology Modeling

Marcus Malo²,
Dr. Lars Brive³,
Prof. Kristina Luthman²,
Dr. Peder Svensson^1,*

Article first published online: 7 FEB 2012

DOI: 10.1002/cmdc.201100546

Issue

ChemMedChem

Special Issue: Neuroscience Drug Discovery

Volume 7, Issue 3, pages 483–494, March 5, 2012

Additional Information

How to Cite

Malo, M., Brive, L., Luthman, K. and Svensson, P. (2012), Investigation of D₁ Receptor–Agonist Interactions and D₁/D₂ Agonist Selectivity Using a Combination of Pharmacophore and Receptor Homology Modeling. ChemMedChem, 7: 483–494. doi: 10.1002/cmdc.201100546

Author Information

¹
NeuroSearch Sweden AB, Arvid Wallgrens Backe 20, 413 46 Göteborg (Sweden)
²
Department of Chemistry, Medicinal Chemistry, University of Gothenburg, 412 96 Göteborg (Sweden)
³
Department of Biomedicine, University of Gothenburg, P.O. Box 440, 405 30, Göteborg (Sweden)

Email: Dr. Peder Svensson (psv@neurosearch.com)

^*NeuroSearch Sweden AB, Arvid Wallgrens Backe 20, 413 46 Göteborg (Sweden)

Publication History

Issue published online: 1 MAR 2012
Article first published online: 7 FEB 2012
Manuscript Revised: 5 JAN 2012
Manuscript Received: 22 NOV 2011

Funded by

Funded Access
Knut and Alice Wallenberg Foundation
The Swedish Research Council

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Investigation of D1 Receptor–Agonist Interactions and D1/D2 Agonist Selectivity Using a Combination of Pharmacophore and Receptor Homology Modeling

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