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Keywords:

  • demyelinating diseases;
  • fluorescent probes;
  • imaging agents;
  • spinal cord demyelination;
  • two-photon microscopy
Thumbnail image of graphical abstract

The back cover picture shows 4-((E)-4-((E)-4-aminostyryl)-2,5-dimethoxystyryl)-N-methylaniline, a fluorescent imaging probe, termed CIC, that selectively binds to the myelin sheath that encases axons. In vivo imaging of the spinal cord in mouse models provides insight into multiple sclerosis and other demyelinating human diseases. For more details, see the Full Paper by Yanming Wang et al. on p. 2194 ff.