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Keywords:

  • heterobivalent peptide ligands;
  • imaging agents;
  • peptides;
  • PET;
  • tumor targeting
Thumbnail image of graphical abstract

Two-pronged synergism: We review the recently developed approach of using heterobivalent peptide ligands that interact concomitantly with different receptors on tumor cells. These ligands exhibit highly favorable tumor-targeting properties and pave the way for the development of drugs for specific, sensitive, and noninvasive tumor imaging and therapy.