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Keywords:

  • Alzheimer’s disease;
  • imaging agents;
  • neurodegenerative diseases;
  • neurofibrillary tangles;
  • olfactory epithelium
Thumbnail image of graphical abstract

Shedding light on grey matter: Fluorescent trimethine cyanines were evaluated as imaging probes for neurofibrillary tangles in post-mortem brain sections of Alzheimer's disease patients. These probes bind to neurofibrillary tangles with high contrast and selectivity over amyloid β plaques.