SEARCH

SEARCH BY CITATION

Keywords:

  • asymmetric synthesis;
  • carbinols;
  • cytotoxicity;
  • lipids;
  • polyacetylene
Thumbnail image of graphical abstract

Illumination by acetylene: Systematic structural variations in a series of archetypal acetylenic lipids derived from the naturally occurring (S,E)-icos-4-en-1-yn-3-ol allowed the discovery of a series of 3R-like 1,4-di-unsaturated carbinol units with a significant and systematic enantiomeric effect on cytotoxicity.