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cis-[PtII(1R,2R-DACH)(3-acetoxy-1,1-cyclobutanedicarboxylato)], a Water-Soluble, Oxalate-Free and Stable Analogue of Oxaliplatin: Synthesis, Characterization, and Biological Evaluations



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Strong, like ox! A new oxaliplatin derivative that features 3-acetoxy-1,1-cyclobutanedicarboxylate as the leaving group has good aqueous solubility and stability. It exhibits higher antitumor activity and greater tolerability than oxaliplatin.

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