Discovery of Isoerianin Analogues as Promising Anticancer Agents (pages 488–497)
Dr. Samir Messaoudi, Dr. Abdallah Hamze, Dr. Olivier Provot, Bret Tréguier, Dr. Jordi Rodrigo De Losada, Dr. Jérôme Bignon, Dr. Jian-Miao Liu, Dr. Joanna Wdzieczak-Bakala, Sylviane Thoret, Dr. Joëlle Dubois, Prof. Jean-Daniel Brion and Dr. Mouad Alami
Article first published online: 14 JAN 2011 | DOI: 10.1002/cmdc.201000456
Breaking the cell cycle: We studied the anticancer activity of a series of new isoerianin derivatives bearing modifications at the A and B rings. Isoerianin was selected as a lead compound for its high antitumor activity.