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Keywords:

  • Chemical shift imaging;
  • multiplex;
  • gadolinium

ABSTRACT

Proton-based chemical shift imaging probes were encapsulated inside nano-carriers to increase the sensivitity of the reporters. Co-encapsulation with a relaxation agent results in improved sensitivity and suppresses background signals. Simultaneous imaging of different chemical shift reporters allows multiplexed detection. Copyright © 2011 John Wiley & Sons, Ltd.