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An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet-B radiation

  1. William B. Grant Ph.D.†,*

Article first published online: 15 MAR 2002

DOI: 10.1002/cncr.10427

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Cancer

Cancer

Volume 94, Issue 6, pages 1867–1875, 15 March 2002

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Grant, W. B. (2002), An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet-B radiation. Cancer, 94: 1867–1875. doi: 10.1002/cncr.10427

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  1. Independent Researcher, Newport News, Virginia

  1. †

    Fax: (757) 864-7790

*12 Sir Francis Wyatt Place, Newport News, VA 23606-3660

Publication History

  1. Issue published online: 15 MAR 2002
  2. Article first published online: 15 MAR 2002
  3. Manuscript Accepted: 20 NOV 2001
  4. Manuscript Revised: 7 NOV 2001
  5. Manuscript Received: 19 MAR 2001

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REFERENCES

  • 1
    Devesa SS, Grauman DJ, Blot WJ, Pennello GA, Hoover RN, Fraumeni JF Jr. Atlas of Cancer Mortality in the United States, 1950–1994. Bethesda (MD): National Institutes of Health; 1999. NIH Publ. No. 99-4564. Available from URL: http://cancer.gov/atlasplus/new.html [accessed October 22, 2001].
  • 2
    Gorham ED, Garland FC, Garland CF. Sunlight and breast cancer incidence in the USSR. Int J Epidemiol. 1990; 19: 820–824.
  • 3
    Grant WB. An ecologic study of the role of solar UV-B radiation in reducing the risk of cancer using cancer mortality data, dietary supply data and latitude for European countries. In: Holick MF, (editor.), Biologic effects of light 2001. Presented in: Proceedings of the Biologic Effects of Light Symposium, Boston, Massachusetts, June 15–17, 2001. In press.
  • 4
    Grant WB. An ecologic study of dietary and solar UV-B links to breast cancer mortality rates. Cancer. In press.
  • 5
    Doll R, Peto R. The causes of cancer. J Natl Cancer Inst. 1981; 66: 1191–1308.
  • 6
    Potter JD, et al. Food, nutrition and the prevention of cancer: a global perspective. Washington, DC: World Cancer Research Fund and American Institute for Cancer Research, 1997: 670.
  • 7
    U.S. Department of Agriculture, Human Nutrition Information Service. Food and nutrient intakes: individuals in four regions, 1977–78. Washington, DC: NFCS 1977–78, Report No. I-3, 1985.
  • 8
    Michaud doMS, Clinton SK, Rimm EB, Willett WC, Giovannucci E. Risk of bladder cancer by geographic region in a U.S. cohort of male health professionals. Epidemiology. 2001; 12: 719–726.
  • 9
    Lee JK, Park BJ, Yoo KY, Ahn YO. Dietary factors and stomach cancer: a case-control study in Korea. Int J Epidemiol. 1995; 24: 33–41.
  • 10
    Laden F, Collman G, Iwamoto K, et al. 1, 1-Dichloro-2, 2-bis (p-chlorophenyl)ethylene and polychlorinated biphenyls and breast cancer: combined analysis of five U.S. studies. J Natl Cancer Inst. 2001; 93: 768–776.
  • 11
    Gorham ED, Garland CF, Garland FC. Acid haze air pollution and breast and colon cancer mortality in 20 Canadian cities. Can J Public Health. 1989; 80: 96–100.
  • 12
    Garland FC, Garland CF, Gorham ED, Young JF. Geographic variation in breast cancer mortality in the United States: a hypothesis involving exposure to solar radiation. Prev Med. 1990; 19: 614–622.
  • 13
    Garland CF, Garland FC. Do sunlight and vitamin D reduce the likelihood of colon cancer? Int J Epidemiol. 1980; 9: 227–231.
  • 14
    Hartge P, Devessa SS, Graumen D, Fears TR, Fraumeni JF. Non-Hodgkin's lymphoma and sunlight. J Natl Cancer Inst. 1996; 88: 298–300.
  • 15
    Freedman DM, Zahm SH, Dosemeci M. Residential and occupational exposure to sunlight and mortality from non-Hodgkin's lymphoma: composite (threefold) case-control study. BMJ. 1997; 314: 1451–1455.
  • 16
    Lefkowitz ES, Garland CF. Sunlight, vitamin D, and ovarian cancer mortality rates in U.S. women. Int J Epidemiol. 1994; 23: 1133–1136.
  • 17
    Schwartz GG, Hulka BS. Is vitamin D deficiency a risk factor for prostate cancer? (hypothesis). Anticancer Res. 1990; 10: 1307–1307.
  • 18
    Hanchette CL, Schwartz GG. Geographic patterns of prostate cancer mortality. Cancer. 1992; 70: 2861–2869.
    Direct Link:
  • 19
    Feldman D, Zhao XY, Krishnan AV. Editorial/mini-review: vitamin D and prostate cancer. Endocrinology. 2000; 141: 5–9.
  • 20
    Total Ozone Mapping Spectrometer data. Available from URL: http://jwocky.gsfc.nasa.gov/ [accessed October 22, 2001].
  • 21
    Herman JR, Krotkov N, Celarier E, Larko D, Labow G. Distribution of UV radiation at the Earth's surface from TOMS-measured UV-backscattered radiances. J Geophys Res. 1999; 104: 12,059–12,076.
  • 22
    McKenzie RL, Seckmeyer G, Bais AF, Madronich S. Satellite retrievals of erythemal UV dose compared with ground-based measurements at northern and southern midlatitudes. J Geophys Res. 2001; 106: 24,051–24,062.
  • 23
    USDA UVB Radiation Monitoring Program. Available from URL: http://uvb.nrel.colostate.edu/ [accessed October 22, 2001].
  • 24
    Bigelow DS, Slusser JR, Beaubien AF, Gibson JH. The USDA Ultraviolet Radiation Monitoring Program. Bull Am Meteorol Soc. 1998; 79: 601–615.
  • 25
    Sasaki S, Horacsek M, Kesteloot H. An ecological study of the relationship between dietary fat intake and breast cancer mortality. Prev Med. 1993; 22: 187–202.
  • 26
    Tsuji K, Harashima E, Nakagawa Y, Urata G, Shirataka M. Time-lag effect of dietary fiber and fat intake ratio on Japanese colon cancer mortality. Biomed Environ Sci. 1996; 9: 223–228.
  • 27
    The World Almanac and Book of Facts 2001. Mahwah, NJ: World Almanac Books, 2001: 374.
  • 28
    U.S. Bureau of the Census. Statistical Abstract of the United States: 1994. 114th edition. Washington, DC: U.S. Bureau of the Census, 1994: 17.
  • 29
    Grant WB. Health benefits of solar UV-B radiation: cancer risk reduction. Presented in: Proceedings of SPIE 4482, Ultraviolet Ground- and Space-Based Measurements, Models, and Effects, San Diego, California, July 30–August 1, 2001. In press.
  • 30
    Ainsleigh HG. Beneficial effects of sun exposure on cancer mortality. Prev Med. 1993; 22: 132–140.
  • 31
    Webb AR, Kline L, Holick MF. Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin. J Clin Endocrinol Metab. 1988; 67: 373–378.
  • 32
    Chen TC, Holick MF. Vitamin D autocrine system and cancer. Photodermatol Photoimmunol Photomed. 2001; 17: 140.
  • 33
    Zehnder D, Bland R, Williams MC, et al. Extrarenal expression of 25-hydroxyvitamin D(3)-1 alpha-hydroxylase. J Clin Endocrinol Metab. 2001; 86: 888–894.
  • 34
    Corder EH, Friedman GD, Vogelmann JH, Orentreich N. Seasonal variation in vitamin D-binding protein, and dehydroepiandrosterone: risk of prostate cancer in black and white men. Cancer Epidemiol Biomarkers Prev. 1995; 4: 655–659.
  • 35
    John EM, Schwartz GG, Dreon DM, Koo J. Vitamin D and breast cancer risk: the NHANES I epidemiologic follow-up study, 1971–1975 to 1992. National Health and Nutrition Examination Survey. Cancer Epidemiol Biomarkers Prev. 1999; 8: 399–406.
  • 36
    Tangrea J, Helzlsouer K, Pietinen P, et al. Serum levels of vitamin D metabolites and the subsequent risk of colon and rectal cancer in Finnish men. Cancer Causes Control. 1997; 8: 615–625.
  • 37
    Pritchard RS, Baron JA, Gerhardsson de Verdier M. Dietary calcium, vitamin D, and the risk of colorectal cancer in Stockholm, Sweden. Cancer Epidemiol Biomarkers Prev. 1996; 5: 897–900.
  • 38
    Ingles SA, Garcia DG, Wang W, et al. Vitamin D receptor genotype and breast cancer in Latinas (United States). Cancer Causes Control. 2000; 11: 25–30.
  • 39
    Kim HS, Newcomb PA, Ulrich CM, et al. Vitamin D receptor polymorphism and the risk of colorectal adenomas: evidence of interaction with dietary vitamin d and calcium. Cancer Epidemiol Biomarkers Prev. 2001; 10: 869–874.
  • 40
    Slattery ML, Yakumo K, Hoffman M, Neuhausen S. Variants of the VDR gene and risk of colon cancer (United States). Cancer Causes Control. 2001; 12: 359–364.
  • 41
    Ingles SA, Ross RK, Yu MC, et al. Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor. J Natl Cancer Inst. 1997; 89: 166–170.
  • 42
    Speer G, Dworak O, Cseh K, et al. Vitamin D receptor gene BsmI polymorphism correlates with erbB-2/HER-2 expression in human rectal cancer. Oncology. 2000; 58: 242–247.
  • 43
    Zhao XY, Peehl DM, Navone NM, Feldman D. 1alpha, 25-dihydroxyvitamin D3 inhibits prostate cancer cell growth by androgen-dependent and androgen-independent mechanisms. Endocrinology. 2000; 141: 2548–2456.
  • 44
    DeLuca HF, Ostrem V. The relationship between the vitamin D system and cancer. Adv Exp Med Biol. 1986; 206: 413–429.
  • 45
    Hickish T, Cunningham D, Colston K, et al. The effect of 1,25-dihydroxyvitamin D3 on lymphoma cell lines and expression of vitamin D receptor in lymphoma. Br J Cancer. 1993; 68: 688–672.
  • 46
    Ahonen MH, Zhuang YH, Aine R, Ylikomi T, Tuohimaa P. Androgen receptor and vitamin D receptor in human ovarian cancer: growth stimulation and inhibition by ligands. Int J Cancer. 2000; 86: 40–46.
    Direct Link:
  • 47
    Fujioka T, Hasegawa M, Ishikura K, Matsushita Y, Sato M, Tanji S. Inhibition of tumor growth and angiogenesis by vitamin D3 agents in murine renal cell carcinoma. J Urol. 1998; 160: 247–251.
  • 48
    Vandewalle B, Wattez N, Lefebvre J. Effects of vitamin D3 derivatives on growth, differentiation and apoptosis in tumoral colonic HT 29 cells: possible implication of intracellular calcium. Cancer Lett 1995; 97: 99–106.
  • 49
    Yabushita H, Hirata M, Noguchi M, Nakanishi M. Vitamin D receptor in endometrial carcinoma and the differentiation-inducing effect of 1,25-dihydroxyvitamin D3 on endometrial carcinoma cell lines. J Obstet Gynaecol Res. 1996; 22: 529–539.
  • 50
    MacLaughlin J, Anderson RR, Holick MF. Spectral character of sunlight modulates photosynthesis of previtamin D3 and its photoisomers in human skin. Science. 1982; 216: 1001–1003.
  • 51
    Holick MF. Environmental factors that influence the cutaneous production of vitamin D. Am J Clin Nutr. 1995; 61(Suppl): 638S–645S.
  • 52
    Madronich S. Implications of recent total atmospheric ozone measurement for biologically active ultraviolet radiation reaching the Earth's surface. Geophys Res Lett. 1992; 19: 37–40.
  • 53
    Jansen MC, Bueno-de-Mesquita HB, Rasanen L, et al. Cohort analysis of fruit and vegetable consumption and lung cancer mortality in European men. Int J Cancer. 2001; 92: 913–918.
    Direct Link:
  • 54
    Devesa SS, Grauman DJ, Blot WJ, Fraumeni JF Jr. Cancer surveillance series: changing geographic patterns of lung cancer mortality in the United States, 1950 through 1994. J Natl Cancer Inst. 1999; 91: 1040–1950.
  • 55
    Centers for Disease Control, State Tobacco Activities Tracking & Evaluation. Available from URL: http://www2.cdc.gov/nccdphp/osh/state/rpt_epi_display.asp?rpt_id=E1 [accessed October 22, 2001].
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