Adenocarcinoma in situ of the cervix: Sensitivity of detection by cervical smear

Will cytologic screening for adenocarcinoma in situ reduce incidence rates for adenocarcinoma?

Authors

  • Harriet O. Smith M.D.,

    Corresponding author
    1. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico
    • Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of New Mexico Health Sciences Center, 2211 Lomas Boulevard NE, Albuquerque, NM 87131-5286
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    • Fax: (505) 272-6385

  • Luis A. Padilla M.D.

    1. Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico
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Abstract

The sensitivity of routine cytologic screening for the detection of adenocarcinoma in situ (AIS) is comparable to that for high-grade squamous lesions (approximately 50%). Although the authors of the current study are cautiously optimistic that screening for AIS will reduce the incidence of invasive cervical carcinoma, population-based studies published to date continue to demonstrate a rise in adenocarcinoma incidence rates.

Ancillary