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Treatment choices and response rates in African-American women with breast carcinoma
Version of Record online: 18 DEC 2002
Copyright © 2003 American Cancer Society
Supplement: Summit Meeting on Breast Cancer Among African American Women
Volume 97, Issue Supplement 1, pages 246–252, 1 January 2003
How to Cite
Newman, L. A., Theriault, R., Clendinnin, N., Jones, D. and Pierce, L. (2003), Treatment choices and response rates in African-American women with breast carcinoma. Cancer, 97: 246–252. doi: 10.1002/cncr.11015
- Issue online: 18 DEC 2002
- Version of Record online: 18 DEC 2002
- Manuscript Received: 14 SEP 2002
- Manuscript Accepted: 14 SEP 2002
- breast cancer;
- African Americans;
Breast cancer mortality rates are higher among African-American women compared with white American women, yet little is known regarding ethnicity-related variation in patterns of primary surgical treatment, locoregional recurrence rates, and response to induction chemotherapy.
The available literature was reviewed to evaluate outcome from breast-conservation therapy in African-American women and response rates to systemic therapy.
Breast-conservation therapy appears to be underused among African-American women, a pattern that is noted also among white women with breast carcinoma. Higher rates of locoregional recurrence are seen among African-American women regardless of whether they receive breast-conserving treatment or undergo mastectomy, and this appears to be a function of primary tumor biology. Response rates to appropriately delivered systemic therapy are similar for African-American patients and white patients.
Despite the apparent increased aggressiveness of disease seen in African-American women with breast carcinoma, patterns of response to local and systemic therapy are similar to the patterns seen in white women with breast carcinoma. Cancer 2003;97(1 Suppl):246–52. © 2003 American Cancer Society.