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Physical activity levels before and after a diagnosis of breast carcinoma†
The health, eating, activity, and lifestyle (HEAL) study
Version of Record online: 18 MAR 2003
Copyright © 2003 American Cancer Society
Volume 97, Issue 7, pages 1746–1757, 1 April 2003
How to Cite
Irwin, M. L., Crumley, D., McTiernan, A., Bernstein, L., Baumgartner, R., Gilliland, F. D., Kriska, A. and Ballard-Barbash, R. (2003), Physical activity levels before and after a diagnosis of breast carcinoma. Cancer, 97: 1746–1757. doi: 10.1002/cncr.11227
A portion of this work was conducted through the Clinical Research Center at the University of Washington
- Issue online: 18 MAR 2003
- Version of Record online: 18 MAR 2003
- Manuscript Accepted: 18 NOV 2002
- Manuscript Revised: 8 NOV 2002
- Manuscript Received: 11 SEP 2002
- National Cancer Institute. Grant Numbers: N01-CN-75036-20, NO1-CN-05228, NO1-PC-67010, T32 CA09661
- National Institutes of Health. Grant Number: M01-RR-00037
- body weight;
Increased body weight at the time patients are diagnosed with breast carcinoma has been associated with an increased risk of recurrence and reduced survival. Weight gain also is common after diagnosis. Increasing physical activity (PA) after diagnosis may minimize these adverse outcomes. In this population-based study, the authors investigated whether PA levels after diagnosis declined from prediagnosis levels and whether any changes in PA varied by disease stage, adjuvant treatment, patient age, or body mass index (BMI) in 812 patients with incident breast carcinoma (from in situ to Stage IIIa).
Types of sports and household activities and their frequency and duration for the year prior to diagnosis and for the month prior to the interview (i.e., 4–12 months postdiagnosis) were assessed during a baseline interview.
Patients decreased their total PA by an estimated 2.0 hours per week from prediagnosis to postdiagnosis, an 11% decrease (P < 0.05). Greater decreases in sports PA were observed among women who were treated with radiation and chemotherapy (50% decrease) compared with women who underwent surgery only (24% decrease) or who were treated with radiation only (23%; (P < 0.05). Greater decreases in sports PA were observed among obese patients (41% decrease) compared with patients of normal weight (24% decrease; P < 0.05).
PA levels were reduced significantly after patients were diagnosed with breast carcinoma. Greater decreases in PA observed among heavier patients implied a potential for greater weight gain among women who already were overweight. Randomized, controlled trials are needed to evaluate how PA may improve the prognosis for patients with breast carcinoma. Cancer 2003;97:1746–57. © 2003 American Cancer Society.