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Racial disparities in breast carcinoma survival rates†

Separating factors that affect diagnosis from factors that affect treatment

  1. Kenneth C. Chu Ph.D.§,*,
  2. Charisee A. Lamar Ph.D.‡,
  3. Harold P. Freeman M.D.

Article first published online: 19 MAY 2003

DOI: 10.1002/cncr.11411

Issue

Cancer

Cancer

Volume 97, Issue 11, pages 2853–2860, 1 June 2003

Additional Information

How to Cite

Chu, K. C., Lamar, C. A. and Freeman, H. P. (2003), Racial disparities in breast carcinoma survival rates. Cancer, 97: 2853–2860. doi: 10.1002/cncr.11411

Author Information

  1. Center to Reduce Cancer Health Disparities, National Cancer Institute, Bethesda, Maryland

  1. ‡

    National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland

  1. §

    Fax: (301) 435-9225

*Center to Reduce Cancer Health Disparities, National Cancer Institute, Building 6116 Executive Blvd, Room 6029, 9000 Rockville Pike, Bethesda, MD 20892-8341

  1. †

    This article is a US Government work and, as such, is in the public domain in the United States of America.

Publication History

  1. Issue published online: 19 MAY 2003
  2. Article first published online: 19 MAY 2003
  3. Manuscript Accepted: 6 FEB 2003
  4. Manuscript Revised: 31 JAN 2003
  5. Manuscript Received: 9 SEP 2002

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Keywords:

  • breast carcinoma;
  • estrogen receptor;
  • stage distribution;
  • stage specific survival;
  • health disparities

Abstract

BACKGROUND

Black females have lower breast carcinoma survival rates compared with white females. One possible reason is that black females have more advanced-stage breast disease. Another factor may be racial differences in the utilization of cancer treatments.

METHODS

The authors determined racial differences in 6-year stage specific survival rates, adjusting for age and treatments (using estrogen receptor [ER] status), to determine whether there were racial differences in treatment. Racial differences in the stage distributions of breast disease were used to examine the impact of racial factors on breast carcinoma diagnosis.

RESULTS

For all breast carcinoma cases, the stage specific 6-year survival rates, in general, were significantly lower for black females for all stages combined and for Stages I–III in every age group. However, examination by different treatments, as measured by ER status, revealed some different results. Only black women younger than age 50 years with ER-positive tumors and women younger than age 65 years with ER-negative tumors had significantly lower stage-specific survival rates. In addition, the stage distribution analyses showed that black females of every age group had less Stage I breast disease.

CONCLUSIONS

For younger black women (younger than age 50 years), there was evidence of racial differences in treatment for both women with ER-positive tumors and women with ER-negative tumors, as indicated by their lower stage-specific survival rates. In contrast, for black females age 65 years or older with ER-positive or ER-negative tumors, the lack of a significant difference in the stage-specific survival rate suggests that Medicare may help to alleviate racial disparities in cancer treatment. Furthermore, racial differences in the stage distributions indicated the need for earlier diagnosis for black females of every age. cancer 2003;97:2853–60. Published 2003 American Cancer Society.

DOI 10.1002/cncr.11411

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