SEARCH

SEARCH BY CITATION

REFERENCES

  • 1
    Nowell SA, Massengill JS, Williams S, et al. Glucuronidation of 2-hydroxyamino-1-methy-6-phenylimidazo[4,5-b]pyridine by human microsomal UDP-glucuronosyltransferases: identification of specific UGT1A family isoforms involved. Carcinogenesis. 1999; 6: 11081114.
  • 2
    Tephly TR, Burchell B. UDP-glucuronosyltransferases: a family of detoxifying enzymes. Trends Pharmacol Sci. 1990; 11: 276279.
  • 3
    Gueraud F, Paris A. Glucuronidation: a dual control. Gen Pharmacol. 1998; 31: 683688.
  • 4
    Ren Q, Murphy SE, Zheng Z, Lazarus P. O-Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9. Drug Metab Dispos. 2000; 28: 13521360.
  • 5
    MacKenzie PI, Owens IS, Burchell B, et al. The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics. 1997; 7: 255269.
  • 6
    Owens IS, Ritter JK. Gene structure at the human UGT1 locus creates diversity in isozyme structure, substrate specificity, and regulation. Prog Nucleic Acid Res Mol Biol. 1995; 51: 305338.
  • 7
    Jin CJ, Miners JO, Burchell B, Mackenzie PI. The glucuronidation of hydroxylated metabolites of benzo[a]pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP-glucuronosyltransferases. Carcinogenesis. 1993; 14: 26372639.
  • 8
    Grove AD, Kessler FK, Metz RP, Ritter JK. Identification of a rat oltipraz-inducible UDP-glucuronosyltransferase (UGT1A7) with activity towards benzo(a)pyrene-7,8-dihydrodiol. J Biol Chem. 1997; 272: 16211627.
  • 9
    Mojarrabi B, Mackenzie PL. Characterization of two UDP glucuronosyltransferases that are predominantly expressed in human colon. Biochem Biophys Res Commun. 1998; 247: 704709.
  • 10
    Strassburg CP, Strassburg A, Nguyen N, Li Q, Manns MP, Tukey RH. Regulation and function of family 1 and family 2 UDP-glucuronosyltransferase genes (UGT1A, UGT2B) in human oesophagus. Biochem J. 1999; 338: 489498.
  • 11
    Guillemette C, Ritter JK, Auyeung DJ, Kessler FK, Housman DE. Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene. Pharmacogenetics. 2000; 10: 629644.
  • 12
    Strassburg CP, Manns MP, Tukey RH. Expression of the UDP-glucuronosyltransferase 1A locus in human colon. Identification and characterization of the novel extrahepatic UGT1A8. J Biol Chem. 1998; 273: 87198726.
  • 13
    Strassburg CP, Nguyen N, Manns MP, Tukey RH. Polymorphic expression of the UDP-glucuronosyltransferase UGT1A gene locus in human gastric epithelium. Mol Pharmacol. 1998; 54: 647654.
  • 14
    Strassburg CP, Kneip S, Topp J, et al. Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine. J Biol Chem. 2000; 275: 3616436171.
  • 15
    Zheng Z, Fang JL, Lazarus P. Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues. Drug Metab Dispos. 2002; 30: 397403.
  • 16
    Rebbeck TR. Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility. Cancer Epidemiol Biomarkers Prev. 1997; 6: 733743.
  • 17
    Lazarus P, Park JY. Metabolizing enzyme genotype and risk for upper aerodigestive tract cancer. Oral Oncol. 2000; 36: 421431.
  • 18
    Ciotti M, Marrone A, Potter C, Owens IS. Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications. Pharmacogenetics. 1997; 7: 485495.
  • 19
    Levesque E, Beaulieu M, Green MD, Tephly TR, Belanger A, Hum DW. Isolation and characterization of UGT2B15(Y85): a UDP-glucuronosyltransferase encoded by a polymorphic gene. Pharmacogenetics. 1997; 7: 317325.
  • 20
    Levesque E, Beaulieu M, Hum DW, Belanger A. Characterization and substrate specificity of UGT2B4 (E458): a UDP-glucuronosyltransferase encoded by a polymorphic gene. Pharmacogenetics. 1999; 9: 207216.
  • 21
    Coffman BL, King CD, Rios GR, Tephly TR. The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y (268) and UGT2B7H (268). Drug Metab Dispos. 1998; 6: 7377.
  • 22
    Macleod SL, Nowell S, Plaxco J, Lang NP. An allele-specific polymerase chain reaction method for the determination of the D85Y polymorphism in the human UDP-glucuronosyltransferase 2B15 gene in a case-control study of prostate cancer. Ann Surg Oncol. 2000; 7: 777782.
  • 23
    Huang CS, Luo GA, Hwang MC, Yu SC, Yang SS. Variation of the bilirubin uridine-diphosphogluguronosyltransferase 1A gene in healthy Taiwanese. Pharmacogenetics. 2000; 10: 539544.
  • 24
    Burchell B, Hume R. Molecular genetic basis of Gilbert's syndrome [review]. J Gastroenterol Hepatol. 1999; 14: 960966.
  • 25
    Guillemette C, Millikan RC, Newman B, Housman DE. Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans. Cancer Res. 2000; 60: 950956.
  • 26
    Zheng Z, Park JY, Guillemette C, Schantz SP, Lazarus P. The tobacco carcinogen-detoxifying enzyme UGT1A7 and its association with orolaryngeal cancer risk in Caucasians and African Americans. J Natl Cancer Inst. 2001; 93: 14111418.
  • 27
    Vogel A, Kneip S, Barut A, et al. Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene. Gastroenterology. 2001; 121: 11361144.
  • 28
    Fang JL, Beland FA, Doerge DR, et al. Characterization of benzo[a]pyrene-7,8-dihydrodiol glucuronidation by human liver microsomes and over-expressed human UDP-glucuronosyltransferase enzymes. Cancer Res. 2002; 62: 19781986.
  • 29
    Richie JP Jr., Carmella SG, Muscat JE, Scott DG, Akerkar SA, Hecht SS. Differences in the urinary metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in black and white smokers. Cancer Epidemiol Biomarkers Prev. 1997; 6: 783790.
  • 30
    Park JY, Muscat J, Schantz S, Stern JC, Lazarus P. Association between GSTM polymorphisms and risk for oral cancer in African Americans as compared to Caucasians. Pharmacogenetics. 2000; 10: 123131.
  • 31
    Elahi A, Zheng Z, Park JY, Eyring K, McCaffrey T, Lazarus P. The human oxoguanine glycosylase 1 (hOGG1) DNA repair enzyme and its association with orolaryngeal cancer risk. Carcinogenesis. 2002; 23: 12291234.
  • 32
    Garte S, Gaspari L, Alexandrie AK, et al. Metabolic gene polymorphism frequencies in control populations. Cancer Epidemiol Biomarkers Prev. 2002; 10: 12391248.
  • 33
    Benhamou S, Benhamou E, Flamant R. Lung cancer risk associated with cigar and pipe smoking. Int J Cancer. 1986; 37: 825829.
  • 34
    National Center for Biotechnology Information. GenBank [database online]. Available from URL: http://www.ncbi.nlm.nih.gov/Genbank/index.html [accessed November 2002]