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Vinblastine, bleomycin, and methotrexate chemotherapy plus irradiation for patients with early-stage, favorable Hodgkin lymphoma
The experience of the Gruppo Italiano Studio Linfomi
Article first published online: 3 NOV 2003
DOI: 10.1002/cncr.11807
Copyright © 2003 American Cancer Society
Additional Information
How to Cite
Gobbi, P. G., Broglia, C., Merli, F., Dell'Olio, M., Stelitano, C., Iannitto, E., Federico, M., Bertè, R., Luisi, D., Molica, S., Cavalli, C., Dezza, L. and Ascari, E. (2003), Vinblastine, bleomycin, and methotrexate chemotherapy plus irradiation for patients with early-stage, favorable Hodgkin lymphoma. Cancer, 98: 2393–2401. doi: 10.1002/cncr.11807
Publication History
- Issue published online: 17 NOV 2003
- Article first published online: 3 NOV 2003
- Manuscript Accepted: 22 AUG 2003
- Manuscript Revised: 18 AUG 2003
- Manuscript Received: 3 JUN 2003
Funded by
- Ministero dell'Università (Rome, Italy)
- Adolfo Ferrata e Edoardo Storti Foundation (Pavia, Italy)
REFERENCES
- 1. Problems in Hodgkin's disease management. Blood. 1999; 93: 761–779.
- 2, , , et al. Vinblastine, bleomycin, and methotrexate: an effective adjuvant chemotherapy in favorable Hodgkin's disease. J Clin Oncol. 1988; 6: 1822–1831.
- 3, , , et al. Preliminary results of the EORTC-GPMC controlled clinical trial H7 in early stage Hodgkin's disease. EORTC Lymphoma Cooperative Group. Group Pierre-et-Marie-Curie. Ann Oncol. 1994; 5(Suppl 2): 523–529.
- 4, , , et al. British National Lymphoma Investigation: pilot studies of neoadjuvant chemotherapy in clinical Stage IA and IIA Hodgkin's disease. Clin Oncol (R Coll Radiol). 2001; 13: 262–268.
- 5, , , et al. Vinblastine, bleomycin, and methotrexate chemotherapy plus extended-field radiotherapy in early, favorably presenting, clinically staged Hodgkin's patients: the Gruppo Italiano per lo Studio dei Linfomi experience. J Clin Oncol. 1996; 14: 527–533.
- 6, , , et al. Report of a committee convened to discuss the evaluation and staging of patients with Hodgkin's disease. J Clin Oncol. 1989; 7: 1630–1636.
- 7. Average relative dose intensity and the impact on design of clinical trials. Semin Oncol. 1987; 14: 65–74.
- 8, , . The chemotherapy of lymphoma: looking back, moving forward—The Richard and Hinda Rosenthal Foundation Award Lecture. Cancer Res. 1987; 47: 5810–5824.
- 9, , , et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982; 5: 129–137.
- 10, . Statistical methods in medical research (2nd edition). Oxford: Blackwell Scientific, 1987: 296–357.
- 11, , , et al. Reporting outcomes in Hodgkin's disease and lymphoma. J Clin Oncol. 1987; 5: 1670–1672.
- 12. Should poor risk patients with Hodgkin's disease be sorted out for intensive treatments? Leuk Lymphoma. 1995; 15: 31–40.
- 13, , , et al. Conventional-dose salvage combination chemotherapy in patients relapsing with Hodgkin's disease after combination chemotherapy: the low probability for cure. J Clin Oncol. 1992; 10: 210–218.
- 14, . Nonparametric estimation from incomplete observation. J Am Stat Assoc. 1958; 53: 457–481.
- 15
- 16, , , et al. Stanford-Kaiser Permanente G1 study for clinical Stage I to IIA Hodgkin's disease: subtotal lymphoid irradiation versus vinblastine, methotrexate and bleomycin chemotherapy and regional irradiation. J Clin Oncol. 1997; 15: 1736–1744.
- 17, , , et al. Efficacy of the VBM regimen in the treatment of elderly patients with Hodgkin's disease. Haematologica. 2000; 85: 729–732.
- 18, , , et al. Abstract CO-024 [abstract]. Haematologica. 2001; 86(Suppl 10): 19.
- 19, , , et al. Treatment of Hodgkin's disease using intensive chemotherapy followed by irradiation. Int J Radiat Oncol Biol Phys. 1976; 1: 619–626.
- 20, , ,et al. Combined chemotherapy (MOPP or ABVD)-radiotherapy approach in advanced Hodgkin's disease. Cancer Treat Rep. 1977; 61: 769–777.
- 21, . The management of Hodgkin's disease. Cancer. 1975; 36: 796–803.Direct Link:
- 22, . The pulmonary toxicity of antineoplastic agents. Semin Oncol. 1982; 9: 34–42.

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