• 1
    Secker-Walker LM, Lawler SD, Hardisty RM. Prognostic implications of chromosomal findings in acute lymphoblastic leukaemia at diagnosis. BMJ. 1978; 2: 15291530.
  • 2
    Third International Workshop on Chromosomes in Leukemia (1980). Clinical significance of chromosomal abnormalities in acute lymphoblastic leukemia. Cancer Genet Cytogenet. 1981; 4: 111137.
  • 3
    Williams DL, Tsiatis A, Brodeur GM, et al. Prognostic importance of chromosome number in 136 untreated children with acute lymphoblastic leukemia. Blood. 1982; 60: 864871.
  • 4
    Look AT, Roberson PK, Williams DL, et al. Prognostic importance of blast cell DNA content in childhood acute lymphoblastic leukemia. Blood. 1985; 65: 10791086.
  • 5
    Trueworthy R, Shuster J, Look T, et al. Ploidy of lymphoblasts is the strongest predictor of treatment outcome in B-progenitor cell acute lymphoblastic leukemia of childhood: a Pediatric Oncology Group study. J Clin Oncol. 1992; 10: 606613.
  • 6
    Smith M, Arthur D, Camitta B, et al. Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia. J Clin Oncol. 1996; 14: 1824.
  • 7
    Pui C-H, Williams DL, Raimondi SC, et al. Hypodiploidy is associated with a poor prognosis in childhood acute lymphoblastic leukemia. Blood. 1987; 70: 247253.
  • 8
    Heerema NA, Nachman JB, Sather HN, et al. Hypodiploidy with less than 45 chromosomes confers adverse risk in childhood acute lymphoblastic leukemia: a report from the Children's Cancer Group. Blood. 1999; 94: 40364045.
  • 9
    Callen DF, Raphael K, Michael PM, et al. Acute lymphoblastic leukemia with a hypodiploid karyotype with less than 40 chromosomes: the basis for division into two subgroups. Leukemia. 1989; 3: 749752.
  • 10
    Pui C-H, Carroll AJ, Raimondi SC, et al. Clinical presentation, karyotypic characterization, and treatment outcome of childhood acute lymphoblastic leukemia with a near-haploid or hypodiploid less than 45 line. Blood. 1990; 75: 11701177.
  • 11
    Kessous A, Corberand J, Grozdea J, et al. Clone cellulaire a 27 chromosomes dans une leucemie aigue humaine [A cellular clone containing 27 chromosomes in a human acute leukemia]. Nouv Rev Fr Hematol. 1975; 15: 7381.
  • 12
    Prieto F, Badia L, Mayans J, et al. Hipodiploidia de 26 cromosomas en leucemia linfoblastica aguda [Hypodiploidy containing 26 chromosomes in acute lymphoblastic leukemia]. Sangre. 1978; 23: 484488.
  • 13
    Oshimura M, Freeman AI, Sandberg AA. Chromosomes and causation of human cancer and leukemia XXIII. Near-haploidy in acute leukemia. Cancer. 1977; 40: 11431148.
  • 14
    Kaneko Y, Sakurai M. Acute lymphocytic leukemia (ALL) with near-haploidy—a unique subgroup of ALL? Cancer Genet Cytogenet. 1980; 2: 1318.
  • 15
    Chaganti RSK. Near-haploid chromosome-numbers in leukemia: significance to leukemogenesis [abstract]. Am J Hum Genet. 1981; 33: A61.
  • 16
    Brodeur GM, Williams DL, Look AT, et al. Near-haploid acute lymphoblastic leukemia: a unique subgroup with a poor prognosis? Blood. 1981; 58: 1419.
  • 17
    Hoeltge GA, Dyment PG, Slovak ML. Acute lymphocytic leukemia with microblastosis and near haploidy (26 chromosomes): a case report. Med Pediatr Oncol. 1982; 10: 5359.
  • 18
    Stamberg J, Shende A, Lanzkowsky P. Somatic shift to homozygosity for a chromosomal polymorphism in a child with acute lymphoblastic leukemia. Blood. 1986; 67: 350353.
  • 19
    Tallents S, Forster DC, Garson OM, et al. Hybrid biphenotypic acute leukemia with extreme hypodiploidy. Pathology. 1987; 19: 197200.
  • 20
    Nordenson I, Adrian BA, Holmgren G, et al. Near-haploidy in childhood leukemia: a high-risk component. Pediatr Hematol Oncol. 1988; 5: 309314.
  • 21
    Redner A, Hegewisch S, Haimi J, et al. A study of multidrug resistance and cell kinetics in a child with near-haploid acute lymphoblastic leukemia. Leuk Res. 1990; 14: 771777.
  • 22
    Gibbons B, MacCallum P, Watts E, et al. Near haploid acute lymphoblastic leukemia: seven new cases and a review of the literature. Leukemia. 1991; 5: 738743.
  • 23
    Onodera N, McCabe NR, Nachman JB, et al. Hyperdiploidy arising from near-haploidy in childhood acute lymphoblastic leukemia. Genes Chromosomes Cancer. 1992; 4: 331336.
  • 24
    Ritterbach J, Hiddemann W, Beck JD, et al. Detection of hyperdiploid karyotypes (>50 chromosomes) in childhood acute lymphoblastic leukemia (ALL) using fluorescence in situ hybridization (FISH). Leukemia. 1998; 12: 427433.
  • 25
    Chessels JM, Swansbury GJ, Reeves B, et al. Cytogenetics and prognosis in childhood lymphoblastic leukaemia: results of MRC UKALL X. Medical Research Council Working Party in Childhood Leukaemia. Br J Haematol. 1997; 99: 93100.
  • 26
    Ma SK, Chan GCF, Wan TSK, et al. Near-haploid common acute lymphoblastic leukaemia of childhood with a second hyperdiploid line: a DNA ploidy and fluorescence in-situ hybridization study. Br J Haematol. 1998; 103: 750755.
  • 27
    Mukherjee S, Das Gupta A, Khodaiji S, et al. Near-haploidy in myeloid antigen positive childhood acute lymphoblastic leukemia. Am J Hematol. 2001; 67: 276277.
  • 28
    Stark B, Jeison M, Gobuzov R, et al. Near haploid childhood acute lymphoblastic leukemia masked by hyperdiploid line: detection by fluorescence in situ hybridization. Cancer Genet Cytogenet. 2001; 128: 108113.
  • 29
    Rivera GK, Raimondi SC, Hancock ML, et al. Improved outcome in childhood acute lymphoblastic leukaemia with reinforced early treatment and rotational combination chemotherapy. Lancet. 1991; 337: 6166.
  • 30
    Pui C-H, Boyett JM, Rivera GK, et al. Long term results of Total Therapy studies 11, 12 and 13A for childhood acute lymphoblastic leukemia at St. Jude Children's Research Hospital. Leukemia. 2000; 14: 22862294.
  • 31
    MitelmanF, editor. An international system for human cytogenetic nomenclature (1995): recommendations of the international standing committee on human cytogenetic nomenclature. Basel: Karger, 1995: 114 pp.
  • 32
    Raimondi SC, Mathew S, Pui C-H. Cytogenetics as a diagnostic aid for childhood hematologic disorders: conventional cytogenetic techniques, fluorescence in situ hybridization, and comparative genomic hybridization. In: HanausekM, WalaszekZ, editors. Tumor marker protocols (methods in molecular medicine, vol. 14). Totowa, NJ: Humana Press, 1998: 209227.
  • 33
    Shurtleff SA, Buijs A, Behm FG, et al. TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis. Leukemia. 1995; 9: 19851989.
  • 34
    Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958; 53: 457481.
  • 35
    Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep. 1966; 50: 163170.
  • 36
    Pui CH, Evans WE. Acute lymphoblastic leukemia. N Engl J Med. 1998; 339: 605615.
  • 37
    Raimondi SC. Cytogenetics of lymphoid neoplasias. In: MarkHFL, editor. Medical cytogenetics. New York: Marcel Dekker, 2000: 349411.
  • 38
    Carroll AJ, Raimondi SC, Williams DL, et al. tdic(9;12): a nonrandom chromosome abnormality in childhood B-cell precursor acute lymphoblastic leukemia: a Pediatric Oncology Group study. Blood. 1987; 70: 19621965.
  • 39
    Raimondi SC, Privitera E, Williams DL, et al. New recurring chromosomal translocations in childhood acute lymphoblastic leukemia. Blood. 1991; 77: 20162022.
  • 40
    Mahmoud H, Carroll AJ, Behm F, et al. The non-random dic(9;12) translocation in acute lymphoblastic leukemia is associated with B-progenitor phenotype and an excellent prognosis. Leukemia. 1992; 6: 703707.
  • 41
    Slater R, Smit E, Kroes W, et al. A non-random chromosome abnormality found in precursor-B lineage acute lymphoblastic leukaemia: dic(9;20)(p1?3;q11). Leukemia. 1995; 9: 16131619.
  • 42
    Heerema NA, Maben KD, Bernstein J, et al. Dicentric (9;20)(p11;q11) identified by fluoresence in situ hybridization in four pediatric acute lymphoblastic leukemia patients. Cancer Genet Cytogenet. 1996; 92: 111115.
  • 43
    Berger R, Busson-Le Coniat M. Centric and pericentric chromosome rearrangements in hematopoietic malignancies. Leukemia. 1999; 13: 671678.