Article first published online: 6 MAY 2004
Copyright © 2004 American Cancer Society
Volume 100, Issue 12, page 2681, 15 June 2004
How to Cite
Dawson, S. I. (2004), Author reply. Cancer, 100: 2681. doi: 10.1002/cncr.20293
- Issue published online: 2 JUN 2004
- Article first published online: 6 MAY 2004
I thank Dr. Tankó and associates for drawing my attention to their research in the area of glucose disturbances and anthropometric measures of body fat distribution.1 It would have been both relevant and interesting to analyze this confounder among the women in my study.2 However, the original study conducted by Farmer et al.3 was designed to investigate glucose metabolism in mother and the health outcome for the fetus in a large series of pregnant women. Information from this study was stored on the databanks at Aberdeen Maternity Hospital, which is the only obstetric facility in Aberdeen, Scotland, and did not include anthropometric measures of body fat distribution.
The current study was designed specifically to investigate long-term morbidity and mortality in parous women. With the original data files from the study conducted by Farmer et al.,3 a tracing exercise using the Grampian Community Health Index was performed.
The correlation between subclinical maternal glucose intolerance and malignant neoplasms later in life may be an epiphenomenon rather than an indication that glucose intolerance is a risk factor for the development of malignant disease. However, the results of my study were significant and suggest the need for additional research to assess the correlation between gestational glucose intolerance and breast carcinoma risk. As an aside, I would like to point out that very few women in the study were postmenopausal, and none of the women diagnosed with breast carcinoma were postmenopausal.