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Estimating the optimal external-beam radiotherapy utilization rate for genitourinary malignancies
Article first published online: 20 DEC 2004
DOI: 10.1002/cncr.20789
Copyright © 2004 American Cancer Society
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How to Cite
Delaney, G., Jacob, S. and Barton, M. (2005), Estimating the optimal external-beam radiotherapy utilization rate for genitourinary malignancies. Cancer, 103: 462–473. doi: 10.1002/cncr.20789
Publication History
- Issue published online: 20 JAN 2005
- Article first published online: 20 DEC 2004
- Manuscript Accepted: 7 OCT 2004
- Manuscript Revised: 7 SEP 2004
- Manuscript Received: 18 MAY 2004
Funded by
- Australian Commonwealth Department of Health and Ageing
REFERENCES
- 1, , . Estimation of an optimal radiotherapy utilization rate for breast cancer: a review of the evidence. Cancer. 2003; 98: 1977–1986.Direct Link:
- 2, , , . An evidence-based estimate of appropriate radiotherapy utilization rate for breast cancer. Int J Radiat Oncol Biol Phys. 2002; 53: 1240–1253.
- 3, , , . A model for decision making for the use of radiotherapy in lung cancer. Lancet Oncol. 2003; 4: 120–128.
- 4, , , , . Estimating the need for radiotherapy for lung cancer: an evidence-based, epidemiologic approach. Int J Radiat Oncol Biol Phys. 2001; 49: 973–985.
- 5, , , , . An evidence-based estimate of the appropriate radiotherapy utilization rate for colorectal cancer. Int J Radiat Oncol Biol Phys. 2003; 56: 1295–1307.
- 6, , . Estimation of an optimal radiotherapy utilization rate for melanoma. A review of the evidence. Cancer. 2004; 100: 1293–1301.Direct Link:
- 7, , , , . Evidence-based estimate of appropriate radiotherapy utilization rate for prostate cancer. Int J Radiat Oncol Biol Phys. 2003; 55: 51–63.
- 8National Cancer Institute. PDQ cancer information summaries: treatment of renal cell cancer. Available from URL: www.nci.nih.gov [accessed August 29, 2002].
- 9BC Cancer Agency. Cancer management guidelines: renal cancer. Available from URL: http://www.bccancer.bc.ca [accessed August 29, 2002].
- 10National Comprehensive Cancer Network. Clinical practice guidelines in oncology—v.1.2003—kidney cancer. Available from URL: www.nccn.org [accessed August 5, 2003].
- 11National Cancer Institute. PDQ cancer information summaries: treatment of bladder cancer. Available from URL: www.nci.nih.gov [accessed August 29, 2002].
- 12BC Cancer Agency. Cancer management guidelines: bladder cancer. Available from URL: http://www.bccancer.bc.ca [accessed August 29, 2002].
- 13. American Urological Association issues guidelines on the management of bladder cancer. Am Fam Phys. 2000; 61: 3734–3736.
- 14National Comprehensive Cancer Network. Practice guidelines in oncology—v.1.2002—bladder cancer. Available from URL: www.nccn.org [accessed October 31, 2002].
- 15National Cancer Institute. PDQ cancer information summaries: treatment of testicular cancer. Available from URL: www.nci.nih.gov [accessed August 29, 2002].
- 16BC Cancer Agency. Cancer management guidelines: management of testicular cancer. Available from URL: http://www.bccancer.bc.ca [accessed August 28, 2002].
- 17Royal College of Radiologists COIN (Clinical Oncology Information Network) Scottish Intercollegiate Guidelines Network. Guidelines on the management of adult testicular germ cell tumours. Available from URL: http://www.rcr.ac.uk/testicular.htm [accessed August 29, 2002].
- 18National Comprehensive Cancer Network. NCCN practice guidelines for testicular cancer. Oncology. 1998; 12: 417–462.
- 19, , , for the EAU Working Group on Oncological Urology. EAU guidelines on testicular cancer. Eur Urol. 2001; 40: 102–110.
- 20, , , for the German Testicular Cancer Study Group. Interdisciplinary consensus on diagnosis and treatment of testicular germ cell tumors: result of an update conference on evidence-based medicine. Eur Urol. 2001; 40: 372–391.
- 21National Cancer Institute. PDQ cancer information summaries: treatment of prostate cancer. Available from URL: www.nci.nih.gov [accessed October 16, 2001].
- 22National Comprehensive Cancer Network. Clinical practice guidelines in oncology—v.1.2002—prostate cancer. Available from URL: www.nccn.org [accessed August 28, 2002].
- 23Royal College of Radiologists COIN (Clinical Oncology Information Network) and British Association of Urological surgeons. Guidelines on the management of prostate cancer. Available from URL: http://www.rcr.ac.uk/prostate.html [accessed October 16, 2001].
- 24American Society for Therapeutic Radiology and Oncology Consensus Panel. Consensus statements on radiation therapy of prostate cancer: guidelines for prostate re-biopsy after radiation and for radiation therapy with rising prostate-specific antigen levels after radical prostatectomy. J Clin Oncol. 1999; 17: 1155–1163.
- 25National Health and Medical Research Council. Guide to the development, implementation and evaluation of clinical practice guidelines. Appendix B. Canberra: National Health and Medical Research Council, 1998: 56.
- 26Australian Institute of Health and Welfare (AIHW) and Australasian Association of Cancer Registries (AACR). Cancer in Australia 1998. CAN 12. 2001. Cancer Series No 17. Canberra: AIHW.
- 27, , . A new protocol for the followup of renal cell cancer based on pathological stage. J Urol. 1995; 154: 28–31.
- 28, , . Is post-operative radiation for renal cell cancer justified? Radiother Oncol. 1997; 43: 155–157.
- 29, , . Factors of importance for prediction of survival in patients with metastatic renal cell cancer, treated with or without nephrectomy. Scand J Urol Nephrol. 2000; 34: 246–251.
- 30, , , . A stage specific approach to tumor surveillance after radical cystectomy for transitional cell cancer of the bladder. J Urol. 1999; 162: 710–714.
- 31, , , et al. Methotrexate, vinblastine, doxorubicin and cisplatin for advanced transitional cell cancer of the urothelium. Cancer. 1989; 64: 2448–2458.Direct Link:
- 32, , . Pattern of metastases in relation to characteristics of primary tumor and treatment in patients with disseminated urothelial cancer. J Urol. 1996; 155: 111–114.
- 33, , , et al. Patterns of treatment of patients with prostate cancer initially managed with surveillance: results from the CaPSURE database. J Urol. 2000; 164: 81–88.
- 34, . Therapeutic options in the management of incidental cancer of the prostate. Int J Radiat Oncol Biol Phys. 1991; 20: 153–167.
- 35, , . Prostate specific antigen in screening for recurrence following radical prostatectomy for localized prostate cancer. Br J Urol. 1993; 72: 88–91.Direct Link:
- 36, , , et al. Radical prostatectomy for clinically localized prostate cancer: long-term results of 1143 patients from a single institution. J Clin Oncol. 1994; 12: 2254–2263.
- 37. Bayesian statistical modelling. New York: John Wiley & Sons, 2002.
- 38Cancer Statistics Branch, National Cancer Institute. Surveillance, Epidemiology and End Results (SEER) program public-use CD-ROM (1973-1997). Bethesda: National Cancer Institute, 2000.
- 39SA Cancer Registry. Epidemiology of cancer in South Australia (Cancer Series No. 22). Adelaide: South Australian Cancer Registry, 2000.
- 40, , , et al. A prospective survey of radiotherapy practice in 2001 in Sweden. Acta Oncol. 2003; 42: 387–410.
- 41Northern and Yorkshire Cancer Registry and Information Service (NYCRIS). Northern and Yorkshire Cancer Networks. A report on incidence and management for the main sites of cancer 1999. Available from URL: http://www.nycris.org.uk/ [accessed November 25, 2003].
- 42
- 43, , , , . The palliation of brain metastases in a favorable patient population: a randomized clinical trial by the radiation therapy oncology group. Int J Radiat Oncol Biol Phys. 1981; 7: 891–895.
- 44, , , et al. The palliation of brain metastases: final results of the first two studies by the radiation therapy oncology group. Int J Radiat Oncol Biol Phys. 1980; 6: 1–9.
- 45, , , et al. The effect of a single fraction compared to multiple fractions on painful bone metastases: a global analysis of the Dutch Bone Metastasis Study. Radiother Oncol. 1999; 52: 101–109.
- 46, , , et al. Randomised trial of single dose versus fractionated palliative radiotherapy of bone metastases. Radiother Oncol. 1998; 47: 233–240.
- 47, , . The palliation of symptomatic osseous metastases. The final results of the study by the Radiation Therapy Oncology Group. Cancer. 1982; 50: 893–899.Direct Link:
- 48. Surgery or radiotherapy for bladder cancer? [letter to the editor]. Clin Oncol (R Coll Radiol). 2002; 14: 519–520.
- 49, . Management of local recurrence following radical nephrectomy or partial nephrectomy. Urol Clin North Am. 1994; 21: 593–599.
- 50, , , . Follow-up guidelines for nonmetastatic renal cell cancer based on the occurrence of metastases after radical nephrectomy. BJU Int. 1999; 84: 405–411.Direct Link:
- 51, , , . Stage specific guidelines for surveillance after radical nephrectomy for local renal cell cancer. J Urol. 1998; 159: 1163–1167.
- 52, , , et al. The impact of tumor size on clinical outcome in patients with localized renal cell cancer treated by radical nephrectomy. J Urol. 1997; 158: 729–732.
- 53, , , . Incidence of brain metastases in a cohort of patients with cancer of the breast, colon, kidney, lung and melanoma. Cancer. 2002; 94: 2698–2705.Direct Link:
- 54, , , et al. Clinical study of brain metastases of renal cell cancer. Eur Urol. 1999; 36: 230–-235.
- 55, , , et al. Radical nephrectomy plus interferon-alfa-based immunotherapy compared with interferon-alpha alone in metastatic renal-cell cancer: a randomised trial. Lancet. 2001; 358: 966–970.
- 56, . Stage Ta-T1 bladder cancer: the relationship between findings at first followup cystoscopy and subsequent recurrence and progression. J Urol. 2002; 167: 1634–1637.
- 57, , , et al. Radical cystectomy for high risk patients with superficial bladder cancer in the era of orthotopic urinary reconstruction. Cancer. 1995; 76: 833–839.Direct Link:
- 58, , , et al. Intravesical Bacillus Calmette-Guerin therapy prevents tumor progression and death from superficial bladder cancer: ten-year follow-up of a prospective randomized trial. J Clin Oncol. 1995; 13: 1404–1408.
- 59, , , et al. Impact of the number of lymph nodes retrieved on outcome in patients with muscle invasive bladder cancer. J Urol. 2002; 167: 1295–1298.
- 60, , , . Radical transurethral resection and chemotherapy in the treatment of muscle-invasive bladder cancer: a long-term follow-up. BJU Int. 1999; 83: 432–437.Direct Link:
- 61, , , et al. The management of testicular cancer in Victoria, 1988-1993. Med J Aust. 2001; 174: 328–331.
- 62, , . Trends in the incidence of testicular germ cell cancer in Ontario by histological subgroup, 1964-1996. Can Med Assoc J. 1999; 160: 201–205.
- 63, , , et al. Surveillance following orchidectomy for stage I seminoma of the testis. Eur J Cancer. 1993; 29A: 1931–1934.
- 64, , . Early stage and advanced seminoma: role of radiation therapy, surgery and chemotherapy. Semin Oncol. 1998; 25: 160–173.
- 65, , , et al. Radiotherapy after chemotherapy for metastatic seminoma—a diminishing role. Eur J Cancer. 1997; 33: 829–835.
- 66International Germ Cell Cancer Collaborative Group. International germ cell consensus classification: a prognostic factor-based staging system for metastatic germ cell cancers. J Clin Oncol. 1997; 15: 594–603.
- 67, , , et al. Management of stage II seminoma. J Clin Oncol. 1998; 16: 290–294.
- 68, , , et al. Cyclophosphamide and sequential cisplatin for advanced seminoma: long-term follow-up in 52 patients. J Urol. 1987; 138: 789–794.
- 69, , , et al. Cisplatin, vincristine and ifosphamide combination chemotherapy of metastatic seminoma: results of EORTC trial 30874. Br J Cancer. 1995; 71: 619–624.
- 70, , , et al. Cisplatin combination chemotherapy in advanced seminoma. Cancer. 1986; 58: 1625–1629.Direct Link:
- 71, , . The treatment of advanced seminoma with chemotherapy and radiotherapy. Br J Cancer. 1988; 57: 100–104.
- 72, , , et al. Single-agent carboplatinum for advanced seminoma. Cancer. 1993; 72: 237–243.Direct Link:
- 73, , , et al. Chemotherapy of metastatic seminoma: the Southeastern Cancer Study Group Experience. J Clin Oncol. 1987; 5: 1212–1220.
- 74, , , . Germ cell testis cancer: 15-year review. J Surg Oncol. 1996; 62: 30–33.Direct Link:
- 75, , , et al. Salvage chemotherapy for patients with germ cell tumors. The Memorial Sloan-Kettering cancer center experience (1979-1989). Cancer. 1991; 67: 1305–1310.Direct Link:
- 76, , , et al. A Scottish national audit of current patterns of management for patients with testicular non-seminomatous germ-cell tumours. Br J Cancer. 1995; 72: 1303–1306.
- 77, , , et al. A randomized trial of standard chemotherapy v a high-dose chemotherapy regimen in the treatment of poor prognosis nonseminomatous germ-cell tumors. J Clin Oncol. 1988; 6: 1031–1040.
- 78, , , et al. Factors associated with initial therapy for clinically localized prostate cancer: prostate cancer outcomes study. J Natl Cancer Inst. 2001; 93: 1864–1871.
- 79, , , , , . Long-term (15 years) results after radical prostatectomy for clinically localized (stage T2c or lower) prostate cancer. J Urol. 1994; 152: 1850–1857.
- 80, , , et al. Impact of positive surgical margins on prostate cancer recurrence and the use of secondary cancer treatment: data from the CaPSURE database. J Urol. 2000; 163: 1171–1177.
- 81, , . Postoperative nomogram for disease recurrence after radical prostatectomy for prostate cancer. J Clin Oncol. 1999; 17: 1499–1507.
- 82, , , . Stage T1-2 prostate cancer: a multivariate analysis of factors affecting biochemical and clinical failures after radical prostatectomy. Int J Radiat Oncol Biol Phys. 1997; 37: 1043–1052.
- 83, , , . Analysis of clinicopathologic factors predicting outcome after radical prostatectomy. Cancer. 2001; 91: 1414–1422.Direct Link:
- 84, , , , . Prognostic significance of positive surgical margins in radical prostatectomy specimens. J Urol. 1995; 154: 1818–1824.
- 85, , , , , . Positive surgical margins with radical retropubic prostatectomy: anatomic site-specific pathologic analysis and impact on prognosis. Urology. 1999; 54: 682–688.
- 86, . Surgical modifications of radical retropubic prostatectomy to decrease incidence of positive surgical margins. J Urol. 1998; 159: 1281–1285.
- 87, , , , . Clinical and pathological characteristics, and recurrence rates of stage T1C versus T2A or T2B prostate cancer. J Urol. 1999; 161: 1525–1529.
- 88, , , . Prediction of progression following radical prostatectomy. A multivariate analysis of 721 men with long-term follow-up. Am J Surg Pathol. 1996; 20: 286–292.
- 89, , , et al. Early prostate-specific antigen relapse after radical retropubic prostatectomy: prediction on the basis of preoperative and postoperative tumor characteristics. Eur Urol. 1999; 36: 21–30.
- 90, , , , . National patterns of prostate cancer treatment by radical prostatectomy: results of a survey by the American College of Surgeons commission on cancer. J Urol. 1994; 152: 1817–1819.
- 91, , , , . Biological determinants of cancer progression in men with prostate cancer. JAMA. 1999; 281: 1395–1400.
- 92, , . Radical prostatectomy for clinical stage T1-2N0M0 prostatic adenocancer: long-term results. J Urol. 1990; 144: 1180–1184.
- 93, . The results of radical prostatectomy at a community hospital during the prostate specific antigen era. Cancer. 1996; 77: 928–933.Direct Link:
- 94, , , et al. Prognostic significance of pathologic features in localized prostate cancer treated with radical prostatectomy: implications for staging systems and predictive models. J Clin Oncol. 2001; 19: 3692–3705.
- 95, , , , , . Natural history of progression after PSA elevation following radical prostatectomy. JAMA. 1999; 281: 1591–1597.
- 96, , , . Is prostate specific antigen of clinical importance in evaluating outcome after radical prostatectomy? J Urol. 1993; 149: 516-518.
- 97, , , et al. Comparison of goserelin and leuprolide in combined androgen blockade therapy. Urology. 1998; 52: 82–88.
- 98, , , , . Deferred treatment of clinically localized low grade prostate cancer: the experience from a prospective series at the Karolinska hospital. J Urol. 1994; 152: 1757–1760.
- 99, , , . Prognosis of untreated stage A1 prostatic cancer: a study of 94 cases with extended followup. J Urol. 1986; 136: 837–839.

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