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The author outlines his personal experience treating hundreds of patients with head and neck carcinoma using combined high-dose intraarterial cisplatin chemotherapy and concomitant, radiation therapy, and he also highlights the published experience of other investigators, all of whom concluded that the high-dose intensity approach is feasible and highly efficacious. This differs from the results reported in this issue by a group of investigators from the Mayo Clinic.

See referenced original article on pages 559–68, this issue.