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Original Article
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Body composition and time course changes in regional distribution of fat and lean tissue in unselected cancer patients on palliative care—Correlations with food intake, metabolism, exercise capacity, and hormones
Article first published online: 8 APR 2005
DOI: 10.1002/cncr.21013
Copyright © 2005 American Cancer Society
Additional Information
How to Cite
Fouladiun, M., Körner, U., Bosaeus, I., Daneryd, P., Hyltander, A. and Lundholm, K. G. (2005), Body composition and time course changes in regional distribution of fat and lean tissue in unselected cancer patients on palliative care—Correlations with food intake, metabolism, exercise capacity, and hormones. Cancer, 103: 2189–2198. doi: 10.1002/cncr.21013
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Fax: (011) 46 31413892
Publication History
- Issue published online: 28 APR 2005
- Article first published online: 8 APR 2005
- Manuscript Accepted: 30 DEC 2004
- Manuscript Revised: 21 DEC 2004
- Manuscript Received: 5 OCT 2004
Funded by
- Swedish Cancer Society. Grant Number: 2014
- Swedish Research Council. Grant Number: 08712
- Tore Nilson Foundation
- Assar Gabrielsson Foundation (AB Volvo)
- Jubileumskliniken Foundation
- IngaBritt and Arne Lundberg Research Foundation
- Swedish and Göteborg Medical Societies
- Medical Faculty of Göteborg University
REFERENCES
- 1, , , et al. The effect on body composition and exercise performance of home parenteral nutrition when given as adjunct to chemotherapy of testicular carcinoma. Eur J Clin Invest. 1991; 21: 413–420.
- 2, , , et al. Resting energy expenditure in malnourished patients with and without cancer. Gastroenterology. 1984; 87: 402–408.
- 3, , , . Resting energy expenditure in controls and cancer patients with localized and diffuse disease. Ann Surg. 1984; 199: 292–298.
- 4, , , , , . Energy expenditure in malnourished gastrointestinal cancer patients. Cancer. 1984; 53: 1265–1273.
- 5, , , , , . Energy expenditure in malnourished patients with colorectal cancer. Arch Surg. 1986; 121: 789–795.
- 6, , , . Weight loss and low body cell mass in males with lung cancer: relationship with systemic inflammation, acute-phase response, resting energy expenditure, and catabolic and anabolic hormones. Clin Sci (Lond). 1999; 97: 215–223.
- 7, , , . Dietary intake and resting energy expenditure in relation to weight loss in unselected cancer patients. Int J Cancer. 2001; 93: 380–383.
- 8, , . Energy balance and body composition in cancer patients. Cancer Res. 1978; 38: 1801–1807.
- 9, , , et al. Dietary intake, nutritional status and well-being of cancer patients: a prospective study. Eur J Cancer Clin Oncol. 1985; 21: 1449–1459.
- 10, , , et al. Supportive therapy of elderly cancer patients. Crit Rev Oncol Hematol. 2002; 42: 189–211.
- 11, , , , . Evidence that long-term COX-treatment improves energy homeostasis and body composition in cancer patients with progressive cachexia. Int J Oncol. 2004; 24: 505–512.
- 12, , , et al. Protection of metabolic and exercise capacity in unselected weight-losing cancer patients following treatment with recombinant erythropoietin: a randomized prospective study. Cancer Res. 1998; 58: 5374–5379.
- 13, , , , . Palliative nutritional intervention in addition to cyclooxygenase and erythropoietin treatment for patients with malignant disease: effects on survival, metabolism, and function. A randomized prospective study. Cancer. 2004; 100: 1967–1977.
- 14, , , , , . Effects of recombinant erythropoietin in palliative treatment of unselected cancer patients. Clin Cancer Res. 2004; 10: 6855–6864.
- 15, , . Evaluation of the meal model “Matmallen.” A means of estimating consumed amounts of food. Scand J Nutr. 1995; 39: 79–83.
- 16. Food composition tables—energy and nutrients. Uppsala: Swedish National Food Administration, 1993.
- 17, . Urine nitrogen as an independent validatory measure of dietary intake: a study of nitrogen balance in individuals consuming their normal diet. Am J Clin Nutr. 1985; 42: 1276–1289.
- 18, , . A simplified technique for measurements of energy expenditure and substrate oxidation in man. Clin Physiol. 1985; 5: 337–345.
- 19. Body composition of patients with malnutrition and cancer. Summary of methods of assessment. Cancer. 1985; 55(1 Suppl ): 250–253.
- 20, , , et al. Evaluating body composition of Italian prostate cancer patients without metastases. Acta Diabetol. 2003; 40( Suppl 1): S168–S170.
- 21, , , et al. Resistance exercise in men receiving androgen deprivation therapy for prostate cancer. J Clin Oncol. 2003; 21: 1653–1659.
- 22, , , et al. Evaluation of nutritional status in advanced metastatic cancer. Support Care Cancer. 2003; 11: 652–659.
- 23, , , et al. Relationship between weight loss, reduction of body cell mass and inflammatory response in patients with cancer. Br J Surg. 1994; 81: 1011–1014.
- 24, , , , . Body cell mass in cancer-bearing and anorexic patients. JPEN J Parenter Enteral Nutr. 1987; 11: 219–222.
- 25, , . Dietary intakes, resting metabolic rates, and body composition in benign and malignant gastrointestinal disease. BMJ. 1980; 280: 211–215.
- 26, , . Total body protein in chronic diseases and in aging. Ann NY Acad Sci. 2000; 904: 345–352.
- 27, . Body composition in malignant disease. Metabolism. 1987; 36: 290–294.
- 28, , , et al. Changes in body composition during androgen deprivation therapy for prostate cancer. J Clin Endocrinol Metab. 2002; 87: 599–603.
- 29, , , , . The use of bioelectrical impedance analysis to predict total body water in patients with cancer cachexia. Am J Clin Nutr. 1995; 61: 741–745.
- 30, , , et al. Estimation of body composition by bioelectrical impedance in cancer patients. Eur J Clin Nutr. 1990; 44: 749–752.
- 31. The role of body composition measurements in wasting syndromes. Semin Oncol. 1998; 25(2 Suppl 6 ): 12–19.
- 32, . Tissue components of weight loss in cancer patients. A new method of study and preliminary observations. Cancer. 1985; 55(1 Suppl ): 238–249.
- 33, , , et al. Comparison of methods of estimating body fat in normal subjects and cancer patients. Am J Clin Nutr. 1981; 34: 2839–2847.
- 34, , , , . Body composition measurements using DXA and other techniques in tamoxifen-treated patients. Appl Radiat Isot. 1998; 49(5–6): 643–645.
- 35, . Body composition in cachexia resulting from malignant and non-malignant diseases. Cancer. 1980; 46: 2041–2046.
- 36, , , et al. Anti-inflammatory treatment may prolong survival in undernourished patients with metastatic solid tumors. Cancer Res. 1994; 54: 5602–5606.
- 37, , , . Muscle mass: reliable indicator of protein-energy malnutrition severity and outcome. Am J Clin Nutr. 1982; 35(5 Suppl ): 1192–1199.
- 38, , . Relationship between metabolism and peripheral blood mononuclear cell mitochondrial complex I activity before and after a short-term refeeding in weight-losing cancer patients. Clin Nutr. 2003; 22: 247–253.
- 39, , , , . Lack of evidence for elevated breakdown rate of skeletal muscles in weight-losing, tumor-bearing mice. J Natl Cancer Inst. 1983; 71: 341–346.
- 40, , , , . Metabolic balance across the leg in weight-losing cancer patients compared to depleted patients without cancer. Cancer Res. 1982; 42: 4293–4299.
- 41, , , , . Flux of amino acids across the leg in weight-losing cancer patients. Cancer Res. 1984; 44: 386–393.
- 42, , , , . Evaluation of anorexia as the cause of altered protein synthesis in skeletal muscles from nongrowing mice with sarcoma. Cancer Res. 1981; 41: 1989–1996.
- 43, . Update on anorexia and cachexia. Hematol Oncol Clin North Am. 2002; 16: 589–617.
- 44, , . The forearm and leg perfusion techniques in man do not give the same metabolic information. Clin Physiol. 1991; 11: 385–395.
- 45, , , , , . Correlation of body fat distribution with grade of endometrial cancer. Gynecol Oncol. 1997; 65: 138–142.
- 46, , , , , . A comparative study of the influence of malignant tumor on host metabolism in mice and man: evaluation of an experimental model. Cancer. 1978; 42: 453–461.
- 47, , . Nuclear RNA polymerase activity in tumor-host livers. Am J Physiol. 1985; 249(5 Pt 1): E461–E469.
- 48, , , et al. Ibuprofen reduces energy expenditure and acute-phase protein production compared with placebo in pancreatic cancer patients. Br J Cancer. 1995; 72: 185–188.
- 49, , , et al. The effect of polyunsaturated fatty acids on the progress of cachexia in patients with pancreatic cancer. Nutrition. 1996; 12(1 Suppl ): S27–S30.
- 50, , , et al. Lipolysis and lipid oxidation in weight-losing cancer patients and healthy subjects. Metabolism. 2000; 49: 931–936.
- 51, , , . Increased lipid utilization in weight losing and weight stable cancer patients with normal body weight. Eur J Clin Nutr. 1999; 53: 740–745.
- 52, , . Energy balance in nonsmall cell lung carcinoma patients before and after surgical resection of their tumors. Cancer. 1997; 79: 717–723.
- 53, , , et al. What is the role of the insulin-like growth factor system in the pathophysiology of cancer cachexia, and how is it regulated? Clin Endocrinol (Oxf). 2002; 56: 723–733.
- 54, , , , . Reversal of cancer-related wasting using oral supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine. Am J Surg. 2002; 183: 471–479.
- 55, , , . Food intake and body composition in cancer cachexia. Nutrition. 1996; 12(1 Suppl ): S20–S23.
- 56, . Diet composition related to body fat in a multivariate study of 203 men. J Am Diet Assoc. 1996; 96: 771–777.