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Retromolar trigone squamous cell carcinoma treated with radiotherapy alone or combined with surgery
Article first published online: 11 APR 2005
Copyright © 2005 American Cancer Society
Volume 103, Issue 11, pages 2320–2325, 1 June 2005
How to Cite
Mendenhall, W. M., Morris, C. G., Amdur, R. J., Werning, J. W. and Villaret, D. B. (2005), Retromolar trigone squamous cell carcinoma treated with radiotherapy alone or combined with surgery. Cancer, 103: 2320–2325. doi: 10.1002/cncr.21038
- Issue published online: 18 MAY 2005
- Article first published online: 11 APR 2005
- Manuscript Received: 15 NOV 2005
- Manuscript Accepted: 18 JAN 2005
- Manuscript Revised: 12 JAN 2005
- retromolar trigone;
- squamous cell carcinoma;
- treatment outcomes
Treatment outcomes were analyzed for retromolar trigone squamous cell carcinoma.
Between June 1966 and August 2003, 99 patients were treated with radiotherapy alone (35 patients) or radiotherapy combined with surgery (64 patients). Followup ranged from 0.2 to 23.8 years (median, 3.3 yrs). All living patients had followup for at least 1 year.
The 5-year local–regional control rates after definitive radiotherapy versus surgery and radiotherapy were as follows: Stages I–III, 51% and 87%; Stage IV, 42% and 62%; and overall, 48% and 71%, respectively. The 5-year cause-specific survival rates after definitive radiotherapy compared with surgery and radiotherapy were as follows: Stages I–III, 56% and 83%; Stage IV, 50% and 61%; and overall, 52% and 69%, respectively. Multivariate analyses revealed that the likelihood of cure was better with surgery and radiotherapy compared with definitive radiotherapy.
The likelihood of cure after treatment for retromolar trigone squamous cell carcinoma was influenced by the extent of disease and treatment. Patients treated with surgery and radiotherapy had a better outcome than those treated with radiotherapy alone. Cancer 2005. © 2005 American Cancer Society.