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Psychiatric disorders and mental health service use in patients with advanced cancer

A report from the coping with cancer study

  1. Nina S. Kadan-Lottick M.D., M.S.P.H.1,†,*,
  2. Lauren C. Vanderwerker Ph.D.2,3,
  3. Susan D. Block M.D.2,3,4,
  4. Baohui Zhang M.S.2,3,
  5. Holly G. Prigerson Ph.D.2,3

Article first published online: 14 NOV 2005

DOI: 10.1002/cncr.21532

Issue

Cancer

Cancer

Volume 104, Issue 12, pages 2872–2881, 15 December 2005

Additional Information

How to Cite

Kadan-Lottick, N. S., Vanderwerker, L. C., Block, S. D., Zhang, B. and Prigerson, H. G. (2005), Psychiatric disorders and mental health service use in patients with advanced cancer. Cancer, 104: 2872–2881. doi: 10.1002/cncr.21532

Author Information

  1. 1

    Department of Pediatrics, Section of Pediatric Hematology-Oncology, Yale University School of Medicine, New Haven, Connecticut

  2. 2

    Center for Psycho-Oncology and Palliative Care Research, Dana-Farber Cancer Institute, Boston, Massachusetts

  3. 3

    Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts

  4. 4

    Harvard Medical School Center for Palliative Care, Boston, Massachusetts

  1. †

    Fax: (203) 737-2228

*Department of Pediatrics, Section of Pediatric Hematology-Oncology, Yale University School of Medicine, 333 Cedar St. LMP 2073, PO Box 208064, New Haven, CT 06520

Publication History

  1. Issue published online: 8 DEC 2005
  2. Article first published online: 14 NOV 2005
  3. Manuscript Accepted: 29 JUN 2005
  4. Manuscript Revised: 4 MAY 2005
  5. Manuscript Received: 12 JAN 2005

Funded by

  • National Institute of Mental Health. Grant Number: CA106370
  • National Cancer Institute. Grant Numbers: MH56529, MH63892
  • Soros Open Society Institute Project on Death in America Faculty Scholarship
  • RAND/Hartford Interdisciplinary Geriatric Health Research Center grant
  • Fetzer Religion at the End-of-Life grant
  • Claude D. Pepper Older Americans Independence Center grant from the National Institute on Aging. Grant Number: P30AG21342
  • National Center for Research Resources. Grant Number: K12RR17594

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REFERENCES

  • 1
    Ries LA, Wingo PA, Miller DS, et al. The annual report to the nation on the status of cancer, 1973–1997, with a special section on colorectal cancer. Cancer. 2000; 88: 2398–2424.
    Direct Link:
  • 2
    Block SD. Assessing and managing depression in the terminally ill patient. ACP-ASIM End-of-Life Care Consensus Panel. American College of Physicians – American Society of Internal Medicine. Ann Intern Med. 2000; 132: 209–218.
  • 3
    Massie MJ. Prevalence of depression in patients with cancer. J Natl Cancer Inst Monogr. 2004: 57–71.
  • 4
    Besisik SK, Kocabey G, Caliskan Y. Major depression and psoriasis activation due to interferon-alpha in a patient with chronic myeloid leukemia; “overlooked and/or misdiagnosed adverse reaction in malignant disease.” Am J Hematol. 2003; 74: 224.
    Direct Link:
  • 5
    Ito M, Onose M, Yamada T, Onishi H, Fujisawa S, Kanamori H. Successful lithium carbonate treatment for steroid-induced depression following bone marrow transplantation: a case report. Jpn J Clin Oncol. 2003; 33: 538–540.
  • 6
    Geinitz H, Zimmermann FB, Thamm R, Keller M, Busch R, Molls M. Fatigue in patients with adjuvant radiation therapy for breast cancer: long-term follow-up. J Cancer Res Clin Oncol. 2004; 130: 327–333.
  • 7
    Green AI, Austin CP. Psychopathology of pancreatic cancer. A psychobiologic probe. Psychosomatics. 1993; 34: 208–221.
  • 8
    Passik SD, Dugan W, McDonald MV, Rosenfeld B, Theobald DE, Edgerton S. Oncologists' recognition of depression in their patients with cancer. J Clin Oncol. 1998; 16: 1594–1600.
  • 9
    Breitbart W, Rosenfeld B, Pessin H, et al. Depression, hopelessness, and desire for hastened death in terminally ill patients with cancer. JAMA. 2000; 284: 2907–2911.
  • 10
    Portenoy RK, Thaler HT, Kornblith AB, et al. Symptom prevalence, characteristics and distress in a cancer population. Qual Life Res. 1994; 3: 183–189.
  • 11
    Ballenger JC, Davidson JR, Lecrubier Y, Nutt DJ, Jones RD, Berard RM. Consensus statement on depression, anxiety, and oncology. J Clin Psychiatry. 2001; 62(Suppl 8): 64–67.
  • 12
    Derogatis LR, Morrow GR, Fetting J, et al. The prevalence of psychiatric disorders among cancer patients. JAMA. 1983; 249: 751–757.
  • 13
    Chochinov HM, Wilson KG, Enns M, et al. Desire for death in the terminally ill. Am J Psychiatry. 1995; 152: 1185–1191.
  • 14
    Jenkins PL, May VE, Hughes LE. Psychological morbidity associated with local recurrence of breast cancer. Int J Psychiatry Med. 1991; 21: 149–155.
  • 15
    Akechi T, Okuyama T, Sugawara Y, Nakano T, Shima Y, Uchitomi Y. Major depression, adjustment disorders, and post-traumatic stress disorder in terminally ill cancer patients: associated and predictive factors. J Clin Oncol. 2004; 22: 1957–1965.
  • 16
    Power D, Kelly S, Gilsenan J, et al. Suitable screening tests for cognitive impairment and depression in the terminally ill—a prospective prevalence study. Palliat Med. 1993; 7: 213–218.
  • 17
    Maguire P, Walsh S, Jeacock J, Kingston R. Physical and psychological needs of patients dying from colo-rectal cancer. Palliat Med. 1999; 13: 45–50.
  • 18
    Colon EA, Callies AL, Popkin MK, McGlave PB. Depressed mood and other variables related to bone marrow transplantation survival in acute leukemia. Psychosomatics. 1991; 32: 420–425.
  • 19
    Lansky SB, List MA, Herrmann CA, et al. Absence of major depressive disorder in female cancer patients. J Clin Oncol. 1985; 3: 1553–1560.
  • 20
    Sneeuw KCA, Asronson ND, Van Wouwe MCC, et al. Prevalence and screening of psychiatric disorder in patients with early stage breast cancer Int Congr Psychosocial Oncol. 1993; 2: 50–51.
  • 21
    Montazeri A, Jarvandi S, Haghighat S, et al. Anxiety and depression in breast cancer patients before and after participation in a cancer support group. Patient Educ Couns. 2001; 45: 195–198.
  • 22
    Breitbart W, Jacobsen PB. Psychiatric symptom management in terminal care. Clin Geriatr Med. 1996; 12: 329–347.
  • 23
    Fisch MJ, Titzer ML, Kristeller JL, et al. Assessment of quality of life in outpatients with advanced cancer: the accuracy of clinician estimations and the relevance of spiritual well-being—a Hoosier Oncology Group Study. J Clin Oncol. 2003; 21: 2754–2759.
  • 24
    Ford S, Fallowfield L, Lewis S. Doctor-patient interactions in oncology. Soc Sci Med. 1996; 42: 1511–1519.
  • 25
    McDonald MV, Passik SD, Dugan W, Rosenfeld B, Theobald DE, Edgerton S. Nurses' recognition of depression in their patients with cancer. Oncol Nurs Forum. 1999; 26: 593–599.
  • 26
    Vanderwerker L, Laff R, Kadan-Lottick N, McColl S, Prigerson H. Psychiatric disorders and mental health service use among caregivers of terminally Ill cancer patients. J Clin Oncol. 2005; 23: 6899–6907.
  • 27
    Kiernan RJ, Mueller J, Langston JW, Van Dyke C. The Neurobehavioral Cognitive Status Examination: a brief but quantitative approach to cognitive assessment. Ann Intern Med. 1987; 107: 481–485.
  • 28
    First M, Spitzer R, Gibbon M, Wiliiams J. Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition (SCID-I/P, Version 2.0). New York: Biometrics Research Department, New York State Psychiatric Institute, 1995.
  • 29
    Williams JB, Gibbon M, First MB, et al. The Structured Clinical Interview for DSM-III-R (SCID). II. Multisite test-retest reliability. Arch Gen Psychiatry. 1992; 49: 630–636.
  • 30
    Endicott J. Measurement of depression in patients with cancer. Cancer. 1984; 53: 2243–2249.
  • 31
    Breitbart W, Bruera E, Chochinov H, Lynch M. Neuropsychiatric syndromes and psychological symptoms in patients with advanced cancer. J Pain Symptom Manage. 1995; 10: 131–141.
  • 32
    Zubrod C, Schneiderman M, Frei E, Brindley C, Gold G, Shnider B. Appraisal of methods for the study of chemotherapy of cancer in man: comparative therapeutic trial of nitrogen mustard and trimethylene thiophosphoramide. J Chron Dis. 1960; 11: 7–33.
  • 33
    Escalante CP, Weiser MA, Manzullo E, et al. Outcomes of treatment pathways in outpatient treatment of low risk febrile neutropenic cancer patients. Support Care Cancer. 2004; 12: 657–662.
  • 34
    Christakis NA, Escarce JJ. Survival of Medicare patients after enrollment in hospice programs. N Engl J Med. 1996; 335: 172–178.
  • 35
    Gessert CE, Curry NM, Robinson A. Ethnicity and end-of-life care: the use of feeding tubes. Ethn Dis. 2001; 11: 97–106.
  • 36
    Hopwood P, Howell A, Maguire P. Psychiatric morbidity in patients with advanced cancer of the breast: prevalence measured by two self-rating questionnaires. Br J Cancer. 1991; 64: 349–352.
  • 37
    Pinder KL, Ramirez AJ, Black ME, Richards MA, Gregory WM, Rubens RD. Psychiatric disorder in patients with advanced breast cancer: prevalence and associated factors. Eur J Cancer. 1993; 29A: 524–527.
  • 38
    Hammerlid E, Ahlner-Elmqvist M, Bjordal K, et al. A prospective multicentre study in Sweden and Norway of mental distress and psychiatric morbidity in head and neck cancer patients. Br J Cancer. 1999; 80: 766–774.
  • 39
    Kramer JA. Use of the Hospital Anxiety and Depression Scale (HADS) in the assessment of depression in patients with inoperable lung cancer. Palliat Med. 1999; 13: 353–354.
  • 40
    Weissman MM, Bland R, Joyce PR, Newman S, Wells JE, Wittchen HU. Sex differences in rates of depression: cross-national perspectives. J Affect Disord. 1993; 29: 77–84.
  • 41
    Chochinov HM, Wilson KG, Enns M, Lander S. Depression, hopelessness, and suicidal ideation in the terminally ill. Psychosomatics. 1998; 39: 366–370.
  • 42
    Patrick DL, Ferketich SL, Frame PS, et al. National Institutes of Health State-of-the-Science Conference Statement: symptom management in cancer: pain, depression, and fatigue, July 15–17, 2002. J Natl Cancer Inst Monogr. 2004: 9–16.
  • 43
    Coyne JC, Palmer SC, Shapiro PJ, Thompson R, DeMichele A. Distress, psychiatric morbidity, and prescriptions for psychotropic medication in a breast cancer waiting room sample. Gen Hosp Psychiatry. 2004; 26: 121–128.
  • 44
    Reuter K, Raugust S, Bengel J, Harter M. Depressive symptom patterns and their consequences for diagnosis of affective disorders in cancer patients. Support Care Cancer. 2004; 12: 864–870.
  • 45
    Olfson M, Fireman B, Weissman MM, et al. Mental disorders and disability among patients in a primary care group practice. Am J Psychiatry. 1997; 154: 1734–1740.
  • 46
    Watson M, Haviland JS, Greer S, Davidson J, Bliss JM. Influence of psychological response on survival in breast cancer: a population-based cohort study. Lancet. 1999; 354: 1331–1336.
  • 47
    Nakahara Y, Mochizuki Y, Miyamoto Y, et al. Mental state as a possible independent prognostic variable for survival in patients with advanced lung carcinoma. Cancer. 2002; 94: 3006–3015.
    Direct Link:
  • 48
    Joshi N, Breibart WS. Psychopharmacologic management during cancer treatment. Semin Clin Neuropsychiatry. 2003; 8: 241–252.
  • 49
    Potash M, Breitbart W. Affective disorders in advanced cancer. Hematol Oncol Clin North Am. 2002; 16: 671–700.
  • 50
    Greenberg DB. Barriers to the treatment of depression in cancer patients. J Natl Cancer Inst Monogr. 2004: 127–135.
  • 51
    Pirl WF. Evidence report on the occurrence, assessment, and treatment of depression in cancer patients. J Natl Cancer Inst Monogr. 2004: 32–39.
  • 52
    Trask PC. Assessment of depression in cancer patients. J Natl Cancer Inst Monogr. 2004: 80–92.
  • 53
    Crawley L, Payne R, Bolden J, Payne T, Washington P, Williams S. Palliative and end-of-life care in the African American community. JAMA. 2000; 284: 2518–2521.
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