• 1
    Miki Y, Swensen J, Shattuck-Eidens D, et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science. 1994; 266: 6671.
  • 2
    Wooster R, Bignell G, Lancaster J, et al. Identification of the breast cancer susceptibility gene BRCA2. Nature. 1995; 378: 789792.
  • 3
    Bronner CE, Baker SM, Morrison PT, et al. Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature. 1994; 368: 258261.
  • 4
    Fishel R, Lescoe MK, Rao MR, et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell. 1993; 75: 10271038.
  • 5
    Aunoble B, Sanches R, Didier E, Bignon YJ. Major oncogenes and tumor suppressor genes involved in epithelial ovarian cancer. [Review]. Int J Oncol. 2000; 16: 567576.
  • 6
    Berek JS, Martinez-Maza O, Hamilton T, et al. Molecular and biological factors in the pathogenesis of ovarian cancer. Ann Oncol. 1993; (4 Suppl 4 ): 316.
  • 7
    Berchuck A, Kamel A, Whitaker R, et al. Overexpression of HER-2/neu is associated with poor survival in advanced epithelial ovarian cancer. Cancer Res. 1990; 50: 40874091.
  • 8
    Vocke CD, Pozzatti RO, Bostwick DG, et al. Analysis of 99 microdissected prostate carcinomas reveals a high frequency of allelic loss on chromosome 8p12–21. Cancer Res. 1996; 56: 24112416.
  • 9
    Brown MR, Chuaqui R, Vocke CD, et al. Allelic loss on chromosome arm 8p: Analysis of sporadic epithelial ovarian tumors. Gynecol Oncol. 1999; 74: 98102.
  • 10
    Lassus H, Laitinen MPE, Anttonen M, et al. Comparison of serous and mucinous ovarian carcinomas: Distinct pattern of allelic loss at distal 8p and expression of transcription factor GATA-4. Lab Invest. 2001; 81: 517526.
  • 11
    Pribill I, Speiser P, Leary J, et al. High frequency of allelic imbalance at regions of chromosome arm 8p in ovarian carcinoma. Cancer Genet Cytogenet. 2001; 129: 2329.
  • 12
    Wilson PJ, McGlinn E, Marsh A, et al. Sequence variants of DLC1 in colorectal and ovarian tumours. Hum Mutat. 2000; 15: 156165.
  • 13
    Wright K, Wilson PJ, Kerr J, et al. Frequent loss of heterozygosity and three critical regions on the short arm of chromosome 8 in ovarian adenocarcinomas. Oncogene. 1998; 17: 11851188.
  • 14
    Arnold JM, Woollatt E, Chenevix-Trench G. Chromosome 8 genetic analysis and phenotypic characterization of 21 ovarian cancer cell lines. Cancer Genet Cytogenet. 2002; 139: 109114.
  • 15
    Mobus V, Gerharz CD, Press U, et al. Morphological, immunohistochemical and biochemical characterization of 6 newly established human ovarian carcinoma cell lines. Int J Cancer. 1992; 52: 7684.
  • 16
    Kury FD, Schneeberger C, Sliutz G, et al. Determination of HER-2/neu amplification and expression in tumor tissue and cultured cells using a simple, phenol free method for nucleic acid isolation. Oncogene. 1990; 5: 14031408.
  • 17
    Strelow A, Bernardo K, Adam-Klages S, et al. Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death. J Exper Med. 2000; 192: 601611.
  • 18
    Su AI, Cooke MP, Ching KA, et al. Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U S A. 2002; 99: 44654470.
  • 19
    Welsh JB, Zarrinkar PP, Sapinoso LM, et al. Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer. Proc Natl Acad Sci U S A. 2001; 98: 11761181.
  • 20
    Silverberg SG. Histopathologic grading of ovarian carcinoma: a review and proposal. Int J Gynecol Pathol. 2000; 19: 715.
  • 21
    Jones PA, Laird PW. Cancer epigenetics comes of age. Nat Genet. 1999; 21: 163167.
  • 22
    Xu XL, Yu J, Zhang HY, et al. Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. World J Gastroenterol. 2004; 10: 34413454.
  • 23
    Bova GS, Carter BS, Bussemakers MJ, et al. Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer. Cancer Res. 1993; 53: 38693873.
  • 24
    Kelleher D, Levy A, Bova GS, Gilmore R. Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties. Genomics. 1996; 35: 5565.
  • 25
    Xu ZH, Liang L, Wang HF, Gilmore R. HCRP1, a novel gene that contain different catalytic STT3 subunits have distinct enzymatic properties. Mol Cell. 2003; 12: 101111.
  • 26
    Xu ZH, Liang L, Suzuki S, Li TP, Zhao MJ. TMX, a novel gene that is downregulated in disulfide-linked protein. Arch Biochem Biophys. 2004; 423: 8187.
  • 27
    Momoi T. Caspases involved in ER stress-mediated cell death. FASEB J. 2004; 28.
  • 28
    Xu ZH, Liang L, Koyama K, Nakamura Y. HCRP1, a novel gene to chromosome 8p21.3-p22. Genomics. 2003; 24: 404406.
  • 29
    Xu ZH, Bao L, Zimmer WE. HCRP1, a distinct cell cycle distribution. J Cell Biol. 2003; 311: 783793.
  • 30
    Bache KG. Arrest of mammalian ESCRT-I and mediates receptor down-regulation. Cell. 2004; 15: 183192.
  • 31
    Seibold S, Hammet F, Weber M, Galle J, Wanner C, Marx M. Candidate tumor suppressor genes on chromosome 8p21.3-22. Oncogene. 2003; 17.
  • 32
    Matsuo Y, Nishinaka Y, Suzuki S, et al. TMX, a human transmembrane oxidoreductase of the thioredoxin family: the possible role in disulfide-linked protein folding in the endoplasmic reticulum. Arch Biochem Biophys. 2004; 423: 8187.
  • 33
    Bache KG, Slagsvold T, Cabezas A, Rosendal KR, Raiborg C, Stenmark H. The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation. Mol Biol Cell. 2004; 15: 43374346.
  • 34
    Xu ZH, Liang L, Wang HF, Li TP, Zhao MJ. HCRP1, a novel gene that is downregulated in hepatocellular carcinoma, encodes a growth-inhibitory protein. Biochem Biophys Res Comm. 2003; 311: 10571066.
  • 35
    Seibold S, Rudroff C, Weber M, Galle J, Wanner C, Marx M. Identification of a new tumor suppressor gene located at chromosome 8p21.3-22. FASEB J. 2003; 17.
  • 36
    Nouet S, Amzallag N, Li JM, et al. Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP. J Biol Chem. 2004; 279: 2898928997.
  • 37
    Dammermann A, Merdes A. Assembly of centrosomal proteins and microtubule organization depends on PCM-1. J Cell Biol. 2002; 159: 255266.
  • 38
    Kubo A, Tsukita S. Non-membranous granular organelle consisting of PCM-1: subcellular distribution and cell-cycle-dependent assembly/disassembly. J Cell Sci. 2003; 116: 919928.