Proceedings of the consensus conference on breast conservation, April 28 to May 1, 2005, Milan, Italy

Authors

  • Gordon F. Schwartz MBA, MD,

    Corresponding author
    1. Department of Surgery, Jefferson Medical College, Philadelphia, Pennsylvania
    • Department of Surgery, Jefferson Medical College, 1015 Chestnut Street, Suite 510, Philadelphia, PA 19107-4305, U.S.A
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    • Fax: (215) 627-3925

  • Umberto Veronesi MD,

    1. European School of Oncology, Milan, Italy
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  • Krishna B. Clough MD,

    1. Paris Breast Center, Paris, France
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  • J. Michael Dixon MB, ChB,

    1. Edinburgh Breast Unit, Western General Hospital, Edinburgh, Scotland, United Kingdom
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  • Ian S. Fentiman MD, DSc,

    1. Department of Surgical Oncology, Guy's Hospital, London, England, United Kingdom
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  • Sylvia H. Heywang-Köbrunner MD,

    1. Department of Breast Imaging and Intervention, Technical University Munich, Munich, Germany
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  • Roland Holland MD, PhD,

    1. National Expert and Training Center for Breast Cancer Screening, University Medical Center Nijmegen, Nijmegen, The Netherlands
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  • Kevin S. Hughes MD,

    1. Avon Comprehensive Breast Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts
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  • Richard Margolese MD,

    1. Department of Surgery, Jewish General Hospital, Montreal, Quebec, Canada
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  • Ivo A. Olivotto MD,

    1. Division of Radiation Oncology, University of British Columbia, Victoria, British Columbia, Canada
    2. British Columbia Cancer Agency, Victoria, British Columbia, Canada
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  • Juan P. Palazzo MD,

    1. Department of Pathology, Jefferson Medical College, Philadelphia, Pennsylvania
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  • Lawrence J. Solin MD,

    1. Department of Radiation Oncology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
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  • and the Consensus Conference Committee

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    • The following were participants in the 2005 Breast Consensus Conference: Gordon F. Schwartz, MBA, MD (Chairman; Department of Surgery, Jefferson Medical College, Philadelphia, PA); Umberto Veronesi (Co-chairman; European School of Oncology, Milan, Italy); Consensus Committee: Harry Bartelink, MD, PhD (Department of Radiotherapy, The Netherlands Cancer Institute, Amsterdam, The Netherlands); Luigi Cataliotti, MD (Department of Surgery, University of Florence, Florence, Italy); Krishna B. Clough, MD (Paris Breast Center, Paris, France); Domenico M. D'Ugo, MD (Department of Surgery, Sacred Heart Catholic University, Rome, Italy); J. M. Dixon, MB, ChB (Edinburgh Breast Unit, Western General Hospital, Edinburgh, Scotland, UK); Ian S. Fentiman, MD, DSc (Department of Surgical Oncology, Guy's Hospital, London, England, UK); Monica Fornier, MD (Breast Cancer Medical Service, Memorial Sloan-Kettering Cancer Center, New York, NY); Alain Fourquet, MD (Department of Oncological Radiotherapy, Institute Curie, Paris, France); Oreste Gentilini, MD (Department of Surgery, European School of Oncology, Milan, Italy); Sylvia H. Heywang-Köbrunner, MD (Department of Breast Imaging and Intervention, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany); Roland Holland, MD, PhD (National Expert and Training Center for Breast Cancer Screening, University Medical Center Nijmegen, Nijmegen, The Netherlands); Kevin S. Hughes, MD (Avon Comprehensive Breast Evaluation Center, MA General Hospital, Boston, MA); Vincenzo Lattanzio, MD (Servizio di Radiologia Senologica SARIS, Centro Riferimento Regionale, Azienda Ospedaliera Policlinico, Bari, Italy); Beryl McCormick, MD (Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY); Robert E. Mansel, MB, MS (Division of Hospital Specialties, Wales College of Medicine, Cardiff, Wales, UK); Richard Margolese, MD (Department of Surgery, Jewish General Hospital, Montreal, Quebec, Canada); Shahla Masood, MD (Department of Pathology, University of Florida, Jacksonville, FL); Ellen B. Mendelson, MD (Department of Radiology, Northwestern University, Chicago, IL); Ivo A. Olivotto, MD (Division of Radiation Oncology, University of British Columbia and British Columbia Cancer Agency, Victoria, British Columbia, Canada); Juan P. Palazzo, MD (Department of Pathology, Jefferson Medical College, Philadelphia, PA); Lori J. Pierce, MD (Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, MI); Christopher J. Poole, MD (Division of Cancer Studies, University of Birmingham, Birmingham, UK); Emiel J. Th. Rutgers, MD, PhD (Department of Surgery, The Netherlands Cancer Institute, Amsterdam, The Netherlands); Lawrence J. Solin, MD (Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA); Fattaneh Tavassoli, MD (Department of Pathology, Yale University School of Medicine, New Haven, CT); Daniela A. Terribile, MD (Department of Surgery, Sacred Heart Catholic University, Rome, Italy); Michael Untch, MD (Department of Gynecology and Breast Cancer Center, Academic Hospital of the University Charité Berlin, Berlin, Germany); and Umberto Veronesi, MD (European School of Oncology, Milan, Italy).


Abstract

In a single generation the treatment of most women with early-stage breast cancer has changed dramatically. Clinical trials with more than 20 years of follow-up have documented that for appropriately selected patients breast conserving surgery, followed by whole breast irradiation, has an outcome equivalent to mastectomy. The appropriate selection of patients remains controversial. Questions remain regarding the role of new diagnostic imaging modalities, radiation therapy techniques, achieving optimal cosmesis, the choice and the timing of adjuvant chemotherapy, etc. To address these issues, the fifth international consensus conference of the Breast Health Institute, cosponsored by the European Institute of Oncology, was convened in Milan, April 29 through May 1, 2005. This article is a summary of the proceedings.

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