Secular changes in colorectal cancer incidence by subsite, stage at diagnosis, and race/ethnicity, 1992–2001†
Article first published online: 11 JUL 2006
Copyright © 2006 American Cancer Society
Supplement: Descriptive Epidemiology of Colorectal Cancer in the United States, 1998–2001, Utilizing Data from the NPCR and SEER Programs
Volume 107, Issue Supplement 5, pages 1142–1152, 1 September 2006
How to Cite
Cress, R. D., Morris, C., Ellison, G. L. and Goodman, M. T. (2006), Secular changes in colorectal cancer incidence by subsite, stage at diagnosis, and race/ethnicity, 1992–2001. Cancer, 107: 1142–1152. doi: 10.1002/cncr.22011
The ideas and opinions expressed herein are those of the authors, and endorsement by the State of California, Department of Health Services, the National Cancer Institute, and the Centers for Disease Control and Prevention is not intended and should not be inferred.
- Issue published online: 21 AUG 2006
- Article first published online: 11 JUL 2006
- Manuscript Accepted: 21 MAR 2006
- Manuscript Received: 2 MAR 2006
- colon carcinoma;
- rectal carcinoma;
- disease stage
Cancers of the colon and rectum are the third most common malignancy among males and females in the United States, although incidence and mortality have declined in recent years. We evaluated recent trends in colorectal cancer incidence in the United States by subsite and stage at diagnosis.
Data for this analysis included all cases of colorectal cancer diagnosed between 1992 and 2001 and reported to the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) Program. Incidence rates were stratified by gender, race/ethnicity, anatomic subsite, stage at diagnosis, and SEER registry. Trends in incidence over time were measured using the estimated annual percentage change.
The study population included 95,539 males and 93,329 females with colorectal cancer. For all 12 SEER registries combined, incidence declined between 1992 and 2001 by 1.2% per year among males and 0.7% per year (not statistically significant) among females. Rates for non-Hispanic whites declined by an average of 1.3% per year for males and 0.6% per year for females. Overall rates for black, Asian/Pacific Islander, and Hispanic males and females did not change significantly except for a 0.8% decline among Asian/Pacific Islander males. Declines in rates among males and females were most pronounced for tumors of the sigmoid colon.
Colorectal cancer rates decreased in the United States during the 1990s. Decreases were most pronounced among males, among non-Hispanic whites, and for tumors of the sigmoid colon. These reductions are probably dueto the increased use of screening. Cancer 2006. © 2006 American Cancer Society.