Fax: (011) 55 13151223.
Original Article
You have full text access to this OnlineOpen article
Colchicine delays the development of hepatocellular carcinoma in patients with hepatitis virus-related liver cirrhosis
Article first published online: 11 SEP 2006
DOI: 10.1002/cncr.22198
Copyright © 2006 American Cancer Society
Additional Information
How to Cite
Arrieta, O., Rodriguez-Diaz, J. L., Rosas-Camargo, V., Morales-Espinosa, D., de Leon, S. P., Kershenobich, D. and Leon-Rodriguez, E. (2006), Colchicine delays the development of hepatocellular carcinoma in patients with hepatitis virus-related liver cirrhosis. Cancer, 107: 1852–1858. doi: 10.1002/cncr.22198
Publication History
- Issue published online: 3 OCT 2006
- Article first published online: 11 SEP 2006
- Manuscript Accepted: 5 JUL 2006
- Manuscript Revised: 18 JUN 2006
- Manuscript Received: 16 DEC 2005
REFERENCES
- 1. Hepatocellular carcinoma. J Hepatol. 2000; 32(S1): 225–237.
- 2
- 3, , . Trends in survival of patients with hepatocellular carcinoma between 1977 and 1996 in the United States. Hepatology. 2001; 33: 62–65.Direct Link:
- 4, , , et al. Hepatitis-C associated hepatocellular carcinoma. Hepatology. 1990; 12: 589–591.Direct Link:
- 5, . Hepatocellular carcinoma: the high risk patient. J Clin Gastroenterol. 2002; 35(5 Suppl 2 ): S79–85.
- 6, . The epidemiology and prevention of hepatocellular carcinoma. Seminars Oncol. 2001; 28: 441–449.
- 7, . Colchicine: 1998 update. Semin Arthritis Rheum. 1998; 28: 48–59.
- 8, . Microtubules as a target for anticancer drugs. Nat Rev Cancer. 2004; 4: 253–265.
- 9, , , . Effect of colchicine on lymphocytes and monocytes function and its relation to fibroblast proliferation in primary biliary cirrhosis. Hepatology. 1990; 11: 205–209.Direct Link:
- 10, . Microtubules in transcellular movement of procollagen. Nat New Biol. 1972; 238: 257–260.
- 11, . Effects of colchicine on collagenase in cultures of rheumatoid synovium. Arthritis Rheum. 1971; 14: 669–684.Direct Link:
- 12
- 13, . Colchicine for alcoholic and non-alcoholic liver fibrosis or cirrhosis. Liver. 2001; 21: 129–136.Direct Link:
- 14, . Colchicine for alcoholic and non-alcoholic liver fibrosis and cirrhosis. Cochrane Database Syst Rev. 2005; CD002148.
- 15, , , et al. Colchicine treatment of alcoholic cirrhosis: a randomized, placebo-controlled clinical trial of patient survival. Gastroenterology. 2005; 128: 882–890.
- 16, , , , , . Colchicine in the treatment of cirrhosis of the liver. N Engl J Med. 1988; 318: 1709–1713.
- 17. , , et al. Prospective analysis of risk factors for hepatocellular carcinoma in patients with liver cirrhosis. Hepatology. 2003; 37: 520–527.Direct Link:
- 18, , , et al. Predictive score for the development of hepatocellular carcinoma and additional value of liver large cell dysplasia in Western patients with cirrhosis. Hepatology. 1996; 23: 1112–1118.Direct Link:
- 19, , , et al. Clinical and pathologic factors associated with the development of hepatocellular carcinoma in patients with hepatitis virus related cirrhosis: a long-term follow-up study. Clin Oncol. In press .
- 20, , , et al. Analysis of factors affecting the appearance of hepatocellular carcinoma in patients with chronic hepatitis C: a long-term follow-up study after histologic diagnosis. Cancer. 2000; 89: 53–59.
- 21, , , et al. Hepatitis C virus related cirrhosis: time to occurrence of hepatocellular carcinoma and death. Gut. 2000; 47: 131–136.
- 22, , , et al. Risk factors for hepatocellular carcinoma in hepatitis C patients with sustained virologic response to interferon therapy. Liver Int. 2004; 24: 603–610.Direct Link:
- 23, , , et al. A long-term follow-up study on risk factors for hepatocellular carcinoma among Japanese patients with liver cirrhosis. Jpn J Cancer Res. 1998; 89: 1241–1250.
- 24
- 25. Hepatitis C virus and hepatocellular carcinoma. Semin Liver Dis. 1999; 19: 263–269.
- 26, , , et al. Hepatocellular carcinoma in Italian patients with cirrhosis. N Engl J Med. 1991; 325: 675–680.
- 27, , , et al. Prevention of hepatocellular carcinoma development associated with chronic hepatitis by anti-fas ligand antibody therapy. J Exp Med. 2002; 196: 1105–1111.
- 28, . Treatment with colchicine and survival of patients with ascitic cirrhosis: a double-blind randomized trial. Panminerva Med. 1998; 40: 75–81.
- 29

1097-0142/asset/olbannerleft.gif?v=1&s=ca681f5719430b26e1bc15e9ea4c9fc0a7110104)
1097-0142/asset/olbannerright.gif?v=1&s=8142566facf7e76aef9be6c51162a2e920b3b9f9)
1097-0142/asset/cover.gif?v=1&s=a7299bc18f075294c232ade468773cd0672bd470)