• 1
    Stuschke M, Eberhardt W, Pottgen C, et al. Prophylactic cranial irradiation in locally advanced non-small-cell lung cancer after multimodality treatment: long-term follow-up and investigations of late neuropsychologic effects. J Clin Oncol. 1999; 17: 27002709.
  • 2
    Mamon HJ, Yeap BY, Janne PA, et al. High risk of brain metastases in surgically staged IIIA non-small-cell lung cancer patients treated with surgery, chemotherapy, and radiation. J Clin Oncol. 2005; 23: 15301537.
  • 3
    Albain KS, Rusch VW, Crowley JJ, et al. Concurrent cisplatin/etoposide plus chest radiotherapy followed by surgery for stages IIIA (N2) and IIIB non-small-cell lung cancer: mature results of Southwest Oncology Group phase II 8805. J Clin Oncol. 1995; 13: 18801892.
  • 4
    Cox JD, Yesner RA. Adenocarcinoma of the lung: recent results from the Veterans Administration Lung Group. Am Rev Respir Dis. 1979; 120: 10251029.
  • 5
    Carolana H, Suna AY, Bezjaka A, et al. Does the incidence and outcome of brain metastases in locally advanced non-small cell lung cancer justify prophylactic cranial irradiation or early detection? Lung Cancer. 2005; 49: 109115.
  • 6
    Robnett TJ, Machtay M, Stevenson JP, et al. Factors affecting the risk of brain metastases after definitive chemoradiation for locally-advanced non-small-cell lung carcinoma. J Clin Oncol. 2001; 19: 13441349.
  • 7
    Cox JD, Scott CB, Byhardt RW, et al. Addition of chemotherapy to radiation therapy alters failure patterns by cell type within non-small cell carcinoma of lung (NSCCL): analysis of radiation therapy oncology group (RTOG) trials. Int J Radiat Oncol Biol Phys. 1999; 43: 505509.
  • 8
    Andre F, Grunewald D, Pujol JL, et al. Patterns of relapse of N2 nonsmall-cell lung carcinoma patients treated with preoperative chemotherapy. Cancer. 2001; 91: 23942400.
  • 9
    Law A, Karp DD, Dipetrillo T, et al. Emergence of increased cerebral metastasis after high-dose preoperative radiotherapy with chemotherapy in patients with locally advanced nonsmall cell lung carcinoma. Cancer. 2001; 92: 160164.
  • 10
    Russell AH, Pajak TE, Selim HM, et al. Prophylactic cranial irradiation for lung cancer patients at high risk for development of cerebral metastasis: results of a prospective randomized trial conducted by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys. 1991; 21: 637643.
  • 11
    Cox JD, Stanley K, Petrovich Z, et al. Cranial irradiation in cancer of the lung in all cell types. JAMA. 1981; 245: 469472.
  • 12
    Umsawadi T, Valdivieso M, Chen TT, et al. Role of elective brain irradiation during combined chemoradiotherapy for limited disease non-small-cell lung cancer. J Neurooncol. 1984; 2: 253259.
  • 13
    Auperin A, Arriagada R, Pignon JP, et al. Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. N Engl J Med. 1999; 341: 476484.
  • 14
    Sheehan JP, Sun MH, Kondziolka D, et al. Radiosurgery for non-small cell lung carcinoma metastatic to the brain: long-term outcomes and prognostic factors influencing patient survival time and local tumor control. J Neurosurg. 2002; 97: 12761281.
  • 15
    Jawahar A, Matthew RE, Minagar A, et al. Gamma knife surgery in the management of brain metastases from lung carcinoma: a retrospective analysis of survival, local tumor control, and freedom from new brain metastasis. J Neurosurg. 2004; 100: 842847.
  • 16
    Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc. 1958; 53: 547581.
  • 17
    Gaspar LE, Chansky K, Albain KS, et al. Time from treatment to subsequent diagnosis of brain metastases in stage III non-small-cell-lung cancer: a retrospective review by the Southwest Oncology Group. J Clin Oncol. 2005; 23: 29552961.
  • 18
    Ryan GF, Ball Dl, Smith JG. Treatment of brain metastases from primary lung cancer. Int J Radiat Oncol Biol Phys. 1995; 31: 273278.
  • 19
    Komaki R, Scott CB, Sause WT, et al. Induction cisplatin/vinblastine and irradiation versus irradiation in unresectable squamous cell lung cancer: failure patterns by cell type in RTOG 88-08/ECOG 4588. Int J Radiat Oncol Biol Phys. 1997; 39: 537544.
  • 20
    Machtay M, Lee JH, Stevenson JP, et al. Two commonly used neoadjuvant chemoradiotherapy regimens for locally advanced stage III non-small cell lung carcinoma: long-term results and associations with pathologic response. J Thorac Cardiovasc Surg. 2004; 127: 108113.
  • 21
    Pisters KMW, Kris MG, Gralla RJ, et al. Pathologic complete response in advanced non-small-cell lung cancer following preoperative chemotherapy: implications for the design of future non-small cell lung cancer combined modality trials. J Clin Oncol. 1993; 11: 17571162.
  • 22
    Choi NC, Carey RW, Daly W, et al. Potential impact on survival of improve tumor downstaging and resection rate by preoperative twice-daily radiation and concurrent chemotherapy in stage IIIA non-small-cell lung cancer. J Clin Oncol. 1997; 15: 712722.
  • 23
    Tang SG, Tseng CK, Tsay PK, et al. Predictors for patterns of brain relapse and overall survival in patients with non-small cell lung cancer. J Neurooncol. 2005; 73: 153161.
  • 24
    Mehta MP, Tsao MN, Whelan TJ, et al. The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for brain metastases. Int J Radiat Oncol Biol Phys. 2005; 63: 3746.
  • 25
    McDermott MW, Sneed PK. Radiosurgery in metastatic brain cancer. Neurosurgery. 2005; 57: 4553.
  • 26
    Aoyama H, Shirato H, Tago M, et al. Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial. JAMA. 2006; 295: 24832491.
  • 27
    Hoffman R, Sneed PK, McDermott MW, et al. Radiosurgery for brain metastases from primary lung carcinoma. Cancer J. 2001; 7: 121131.
  • 28
    Wronski M, Arbit E, Burt M, et al. Survival after surgical treatment of brain metastases from lung cancer: a follow-up study of 231 patients treated between 1976 and 1991. J Neurosurg. 1995; 83: 605616.
  • 29
    Nussbaum ES, Djalilian HR, Cho KH, et al. Brain metastases. Histology, multiplicity, surgery, and survival. Cancer. 1996; 78: 17811788.
  • 30
    D'Amico TA, Aloia TA, Moore MB, et al. Predicting the sites of metastases from lung cancer using molecular biologic markers. Ann Thorac Surg. 2001; 72: 11441148.
  • 31
    Bubb RS, Komaki R, Hachiya T, et al. Association of Ki-67, p53, and bcl-2 expression of the primary non-small-cell lung cancer lesion with brain metastatic lesion. Int J Radiat Oncol Biol Phys. 2002; 53: 12161224.
  • 32
    Kikuchi T, Daigo Y, Ishikawa N, et al. Expression profiles of metastatic brain tumor of lung adenocarcinomas on cDNA microarray. Int J Oncol. 2006; 28: 799805.