Fax: (510) 608-5085
The burden of liver cancer in Asians and Pacific Islanders in the Greater San Francisco Bay Area, 1990 through 2004†
Version of Record online: 23 MAR 2007
Copyright © 2007 American Cancer Society
Volume 109, Issue 10, pages 2100–2108, 15 May 2007
How to Cite
Chang, E. T., Keegan, T. H. M., Gomez, S. L., Le, G. M., Clarke, C. A., So, S. K. S. and Glaser, S. L. (2007), The burden of liver cancer in Asians and Pacific Islanders in the Greater San Francisco Bay Area, 1990 through 2004. Cancer, 109: 2100–2108. doi: 10.1002/cncr.22642
The ideas and opinions expressed herein are those of the author(s), and endorsement by the State of California, Department of Health Services, the National Cancer Institute, and the Centers for Disease Control and Prevention or their contractors and subcontractors is not intended nor should be inferred.
- Issue online: 25 APR 2007
- Version of Record online: 23 MAR 2007
- Manuscript Accepted: 12 FEB 2007
- Manuscript Revised: 1 FEB 2007
- Manuscript Received: 4 DEC 2006
- California Department of Health Services. Grant Number: 103885
- National Cancer Institute's Surveillance, Epidemiology, and End Results Program
- Northern California Cancer Center. Grant Number: N02-PC-15105
- Public Health Institute
- Centers for Disease Control and Prevention's National Program of Cancer Registries. Grant Number: U55/CCR921930-02
- Asian Americans;
- hepatocellular carcinoma;
- liver cancer;
To the authors' knowledge, no previous U.S. study has examined time trends in the incidence rate of liver cancer in the high-risk Asian/Pacific Islander population. In this study, liver cancer incidence trends were evaluated in Chinese, Filipino, Japanese, Korean, and Vietnamese men and women in the Greater San Francisco Bay Area of California between 1990 and 2004.
Populations at risk were estimated by using the cohort-component demographic method. Annual percentage changes (APCs) in age-adjusted incidence rates of primary liver cancer among Asians/Pacific Islanders in the Greater Bay Area Cancer Registry were calculated by using joinpoint regression analysis.
The incidence rate of liver cancer between 1990 and 2004 did not change significantly in Asian/Pacific Islander men or women overall. However, the incidence rate declined, although the decline was not statistically significant, among Chinese men (APC, −1.6%; 95% confidence interval [95% CI], −3.4–0.3%), Japanese men (APC, −4.9%; 95% CI, −10.7–1.2%), and Japanese women (APC, −3.6%; 95% CI, −8.9–2%). Incidence rates remained consistently high for Vietnamese, Korean, and Filipino men and women. Trends in the incidence rate of hepatocellular carcinoma were comparable to those for liver cancer. Although disparities in liver cancer incidence between Asians/Pacific Islanders and other racial/ethnic groups diminished between the period from 1990 through 1994 and the period from 2000 through 2004, the disparities among Asian subgroups increased.
Liver cancer continues to affect Asian/Pacific Islander Americans disproportionately, with consistently high incidence rates in most subgroups. Culturally targeted prevention methods are needed to reduce the high rates of liver cancer in this growing population in the U.S. Cancer 2007. © 2007 American Cancer Society.