• 1
    Zimm S,Wampler GL,Stablein D,Hazra T,Young HF. Intracerebral metastases in solid tumor patients: natural history and results of treatment. Cancer. 1981; 48: 384394.
  • 2
    Van den Hout WB,Van der Linden YM,Steenland E, et al. Single- versus multiple-fraction radiotherapy in patients with painful bone metastases: cost-utility analysis based on a randomized trial. J Natl Cancer Inst. 2003; 95: 222229.
  • 3
    Harwood AR,Simson WJ. Radiation therapy of cerebral metastases: a randomized prospective clinical trial. Int J Radiat Oncol Biol Phys. 1977; 2: 10911094.
  • 4
    Priestman TJ,Dunn J,Brada M,Rampling R,Baker PG. Final results of the Royal College of Radiologists trial comparing 2 different radiotherapy schedules in the treatment of cerebral metastases. Clin Oncol. 1996; 8: 308315.
  • 5
    Borgelt B,Gelber R,Kramer S, et al. The palliation of brain metastases: final results of the first 2 studies by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys. 1980; 6: 19.
  • 6
    Borgelt B,Gelber R,Karson M, et al. Ultra-rapid high dose irradiation schedules for the palliation of brain metastases: final results of the first 2 studies by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys. 1981; 7: 16331638.
  • 7
    Chatani M,Matayoshi Y,Masaki N,Inoue T. Radiation therapy for brain metastases from lung carcinoma. Prospective randomized trial according to the level of lactate dehydrogenase. Strahlenther Onkol. 1994; 170: 155161.
  • 8
    Lagerwaard FJ,Levendag PC,Nowak PJCM,Eijkenboom WMH,Hanssens PEJ,Schmitz PIM. Identification of prognostic factors in patients with brain metastases: a review of 1292 patients. Int J Radiat Oncol Biol Phys. 1999; 43: 795803.
  • 9
    Gaspar L,Scott C,Rotman M, et al. Recursive partitioning analysis (RPA) of prognostic factors in 3 Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int J Radiat Oncol Biol Phys. 1997; 37: 745751.
  • 10
    Kaplan EL,Meier P. Non parametric estimation from incomplete observations. J Am Stat Assoc. 1958; 53: 457481.
  • 11
    Trotti A,Byhardt R,Stetz J, et al. Common toxicity criteria: version 2.0. An improved reference for grading the acute effects of cancer treatment: impact on radiotherapy. Int J Radiat Oncol Biol Phys. 2000; 47: 1347.
  • 12
    Bruner DW,Wasserman T. The impact on quality of life by radiation late effects. Int J Radiat Oncol Biol Phys. 1995; 31: 13531355.
  • 13
    Joiner MC,Van der Kogel AJ. The linear-quadratic approach to fractionation and calculation of isoeffect relationships. In: SteelGG, editor. Basic Clinical Radiobiology. New York: Oxford University Press; 1997: 106112.
  • 14
    DeAngelis LM,Delattre JY,Posner JB. Radiation-induced dementia in patients cured of brain metastases. Neurology. 1989; 39: 789796.
  • 15
    Haar F,Patterson RHJr. Surgical for metastatic intracranial neoplasm. Cancer. 1972; 30: 12411245.
  • 16
    Ransohoff J. Surgical management of metastatic tumors. Semin Oncol. 1975; 2: 2127.
  • 17
    Patchell RA,Tibbs PA,Walsh JW, et al. A randomized trial of surgery in the treatment of single metastases of the brain. N Engl J Med. 1990; 322: 494500.
  • 18
    Vecht CJ,Haaxma-Reiche H,Noordijk EM, et al. Treatment of single brain metastasis: radiotherapy alone or combined with neurosurgery? Ann Neurol. 1993; 33: 583590.
  • 19
    Pirzkall A,Debus J,Lohr F, et al. Radiosurgery alone or in combination with whole-brain radiotherapy for brain metastases. J Clin Oncol. 1998; 16: 35633569.
  • 20
    Kondziolka D,Patel A,Lunsford LD,Kassam A,Flickinger JC. Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases. Int J Radiat Oncol Biol Phys. 1999; 45: 427434.
  • 21
    Andrews DW,Scott CB,Sperduto PW, et al. Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with 1 to 3 brain metastases: phase III results of the RTOG 9508 randomised trial. Lancet. 2004; 363: 16651672.
  • 22
    Sundstrom JT,Minn H,Lertola KK,Nordman E. Prognosis of patients treated for intracranial metastases with whole-brain irradiation. Ann Med. 1998; 30: 296299.