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Comparison of 7 staging systems for patients with hepatocellular carcinoma undergoing transarterial chemoembolization

  1. Yun Ku Cho MD1,†,*,
  2. Jin Wook Chung MD2,
  3. Jae Kyun Kim MD1,
  4. Yong Sik Ahn MD1,
  5. Mi Young Kim MD1,
  6. Yoon Ok Park MD1,
  7. Wan Tae Kim MD1,
  8. Jong Hoon Byun MD3

Article first published online: 15 NOV 2007

DOI: 10.1002/cncr.23185

Issue

Cancer

Cancer

Volume 112, Issue 2, pages 352–361, 15 January 2008

Additional Information

How to Cite

Cho, Y. K., Chung, J. W., Kim, J. K., Ahn, Y. S., Kim, M. Y., Park, Y. O., Kim, W. T. and Byun, J. H. (2008), Comparison of 7 staging systems for patients with hepatocellular carcinoma undergoing transarterial chemoembolization. Cancer, 112: 352–361. doi: 10.1002/cncr.23185

Author Information

  1. 1

    Department of Radiology, Seoul Veterans Hospital, Seoul, Korea

  2. 2

    Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Seoul, Korea

  3. 3

    Department of Internal Medicine, Seoul Veterans Hospital, Seoul, Korea

  1. †

    Fax (011) 82-82 2225-1488.

*Department of Radiology, Seoul Veterans Hospital, 6-2 Dunchon-dong, Gangdong-gu, Seoul 134-060, Korea

Publication History

  1. Issue published online: 4 JAN 2008
  2. Article first published online: 15 NOV 2007
  3. Manuscript Accepted: 21 AUG 2007
  4. Manuscript Revised: 30 JUL 2007
  5. Manuscript Received: 6 APR 2007

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REFERENCES

  • 1
    Vauthey J,Lauwers GY,Esnaola NF, et al. Simplified staging for hepatocellular carcinoma. J Clin Oncol. 2002; 20: 1527–1536.
  • 2
    Liver Cancer Study Group of Japan. The General Rules for the Clinical and Pathological Study of Primary Liver Cancer. 4th ed. Tokyo, Japan: Kanehara; 2000.
  • 3
    The Cancer of the Liver Italian Program (CLIP) Investigators. A new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients. Hepatology. 1998; 28: 751–755.
    Direct Link:
  • 4
    The Cancer of the Liver Italian Program (CLIP) Investigators. Prognostic validation of the CLIP score: a new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients. Hepatology. 2000; 31: 840–845.
    Direct Link:
  • 5
    Llovet JM,Bru C,Bruix J. Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin Liver Dis. 1999; 16: 329–338.
  • 6
    Kudo M,Chung H,Osaki Y. Prognostic staging system for hepatocellular carcinoma (CLIP score): its value and limitations, and a proposal for a new staging system, the Japan Integrated Staging Score (JIS score). J Gastroenterol. 2003; 38: 207–215.
  • 7
    Leung TW,Tang AM,Zee B, et al. Construction of the Chinese University Prognostic Index for Hepatocellular Carcinoma and comparison with the TNM staging system, the Okuda staging system, and the Cancer of the Liver Italian Program staging system: a study based on 926 patients. Cancer. 2002; 94: 1760–1769.
    Direct Link:
  • 8
    Nakamura H,Hashimoto T,Oi H, et al. Transcatheter oil chemoembolization of hepatocellular carcinoma. Radiology. 1989; 170: 783–786.
  • 9
    Bronowicki JP,Vetter D,Dumas F, et al. Transcatheter oily chemoembolization for hepatocellular carcinoma: a 4-year study of 127 French patients. Cancer. 1994; 74: 16–24.
    Direct Link:
  • 10
    Takayasu K,Muramatsu Y,Maeda T, et al. Targeted transarterial oily chemoembolization for small foci of hepatocellular carcinoma using a unified helical CT and angiography system: analysis of factors affecting local recurrence and survival rates. AJR Am J Roentgenol. 2001; 176: 681–688.
  • 11
    Lencioni R,Allgaier H,Cioni D, et al. Small hepatocellular carcinoma in cirrhosis: randomized comparison of radiofrequency thermal ablation versus percutaneous ethanol injection. Radiology. 2003; 228: 235–240.
  • 12
    Huo TI,Lin HC,Hwang YH, et al. The Model for End-stage Liver Disease-based Japan Integrated Scoring System may have a better predictive ability for patients with hepatocellular carcinoma undergoing locoregional therapy. Cancer. 2006; 107: 141–147.
    Direct Link:
  • 13
    Huo TI,Huang YH,Lin HC, et al. Proposal of a modified Cancer of the Liver Italian Program staging system based on the Model for End-stage Liver Disease for patients with hepatocellular carcinoma undergoing loco-regional therapy. Am J Gastroenterol. 2006; 101: 975–982.
    Direct Link:
  • 14
    Georgiades CS,Liapi E,Frangakis C, et al. Prognostic accuracy of 12 liver staging systems in patients with unresectable hepatocellular carcinoma treated with transarterial chemoembolization. J Vasc Interv Radiol. 2006; 17: 1619–1624.
  • 15
    Bruix J,Sherman M,Llovet JM, et al. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona 2000 EASL conference. J Hepatol. 2001; 35: 421–430.
  • 16
    Sorensen JB,Klee M,Palshof T, et al. Performance status assessment in cancer patients. An interobserver variability study. Br J Cancer. 1993; 67: 773–775.
  • 17
    Malinchoc M,Kamath PS,Gordon FD, et al. A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Hepatology. 2000; 31: 864–871.
    Direct Link:
  • 18
    Tateishi R,Yoshida H,Shiinna H, et al. Proposal of a new prognostic model for hepatocellular carcinoma: an analysis of 403 patients. Gut. 2005; 54: 419–425.
  • 19
    Cox DR. Regression models and life-tables (with discussion). J R Stat Soc B. 1972; 34: 187–220.
  • 20
    Ueno S,Tanabe G,Sako K, et al. Discrimination value of the new western prognostic system (CLIP score) for hepatocellular carcinoma in 662 Japanese patients. Hepatology. 2001; 34: 529–534.
    Direct Link:
  • 21
    Akaike H. A new look at statistical model identification. IEEE Trans Automatic Control. 1974; AC19: 716–723.
  • 22
    Harrell FEJr,Califf RM,Pryor DB, et al. Evaluating the yield of medical tests. JAMA. 1982; 247: 2543–2546.
  • 23
    Cilo U,Bassanello M,Vitale A, et al. The critical issue of hepatocellular carcinoma prognostic classification: which is the best tool available? J Hepatol. 2004; 40: 124–131.
  • 24
    Testa R,Testa E,Giannini E, et al. Trans-catheter arterial chemoembolization for hepatocellular carcinoma in patients with viral hepatitis: role of combined staging systems, Cancer of the Liver Italian Program (CLIP) and Model for End-stage Liver Disease (MELD), in predicting outcome after treatment. Aliment Pharmacol Ther. 2003; 17: 1563–1569.
    Direct Link:
  • 25
    Brown DB,Fundakowski CE,Lisker-Melman M, et al. Comparison of MELD and Child-Pugh scores to predict survival after chemoembolization for hepatocellular carcinoma. JVasc Interv Radiol. 2004; 15: 1209–1218.
  • 26
    Toyoda H,Kumada T,Kiriyama S, et al. Comparison of the usefulness of 3 staging systems for hepatocellular carcinoma (CLIP, BCLC, and JIS) in Japan. Am J Gastroenterol. 2005; 100: 1764–1771.
    Direct Link:
  • 27
    Henderson JM,Sherman M,Tavil A,Abecassis M,Chejfec G,Gramlich T. AHPBA/AJCC consensus conference on staging of hepatocellular carcinoma: consensus statement. HPB. 2003; 5: 243–250.
    Direct Link:
  • 28
    O'Suilleabhain CB,Poon RT,Yong JL, et al. Factors predictive of 5-year survival after transarterial chemoembolization for inoperable hepatocellular carcinoma. Br J Surg. 2003; 90: 325–331.
    Direct Link:
  • 29
    Stefanini GF,Amorati P,Biselli M, et al. Efficacy of transarterial targeted treatments on survival of patients with hepatocellular carcinoma: an Italian experience. Cancer. 1995; 75: 2427–2434.
    Direct Link:
  • 30
    Izumi R,Shimizu K,Ii T, et al. Prognostic factors of hepatocellular carcinoma in patients undergoing hepatic resection. Gastroenterology. 1994; 106: 720–727.
  • 31
    Tsai TJ,Chau GY,Lui WY, et al. Clinical significance of microscopic tumor venous invasion in patients with respectable hepatocellular carcinoma. Surgery. 2000; 127: 603–608.
  • 32
    Jonas S,Bechstein WO,Steinmuller T, et al. Vascular invasion and histopathologic grading determine outcome after liver transplantation for hepatocellular carcinoma in cirrhosis. Hepatology. 2001; 33: 1080–1086.
    Direct Link:
  • 33
    Cillo U,Vitale A,Grigoletto F, et al. Prospective validation of the Barcelona Clinic Liver Cancer staging system. JHepatol. 2006; 44: 723–731.
  • 34
    Marrero JA,Fontana RJ,Barrat A, et al. Prognosis of hepatocellular carcinoma: comparison of 7 staging systems in an American cohort. Hepatology. 2005; 41: 707–715.
    Direct Link:
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