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Supplement
Burden of potentially human papillomavirus-associated cancers of the oropharynx and oral cavity in the US, 1998–2003†‡§
Article first published online: 3 NOV 2008
DOI: 10.1002/cncr.23745
Published 2008 by the American Cancer Society
Issue
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Cancer
Supplement: Assessing the Burden of HPV-Associated Cancers in the United States
Volume 113, Issue Supplement 10, pages 2901–2909, 15 November 2008
Additional Information
How to Cite
Ryerson, A. B., Peters, E. S., Coughlin, S. S., Chen, V. W., Gillison, M. L., Reichman, M. E., Wu, X., Chaturvedi, A. K. and Kawaoka, K. (2008), Burden of potentially human papillomavirus-associated cancers of the oropharynx and oral cavity in the US, 1998–2003. Cancer, 113: 2901–2909. doi: 10.1002/cncr.23745
- †
This article is a US Government work and, as such, is in the public domain in the United States of America.
- ‡
We appreciate the in-kind support from all the contributors to this supplement. We also thank Amy Chen, MD, MPH, for her input on the categorization of anatomic sites for this analysis.
- §
The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention.
Publication History
- Issue published online: 3 NOV 2008
- Article first published online: 3 NOV 2008
- Manuscript Accepted: 2 JUN 2008
- Manuscript Revised: 29 MAY 2008
- Manuscript Received: 14 APR 2008
Funded by
- Cooperative Agreement. Grant Number: U50 DP424071-04
- Centers for Disease Control and Prevention (CDC)
REFERENCES
- 1,,,,,. Cancer statistics, 2007. CA Cancer Clin. 2007; 57: 43–66.Direct Link:
- 2U.S. Cancer Statistics Working Group. U.S. cancer statistics: 2004 incidence and mortality. Atlanta, GA: Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute; 2007.
- 3. Epidemiology of head and neck cancer: magnitude of the problem. Cancer Metastasis Rev. 2005; 24: 9–17.
- 4,,,. Oral cavity and oropharynx tumors. Radiol Clin North Am. 2007; 45: 1–20.
- 5,,, et al. Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res. 1988; 48: 3282–3287.
- 6,,, et al. Racial differences in risk of oral and pharyngeal cancer: alcohol, tobacco, and other determinants. J Natl Cancer Inst. 1993; 85: 465–473.
- 7,,, et al. Human papillomavirus 16 and head and neck squamous cell carcinoma. Int J Cancer. 2007; 120: 2386–2392.Direct Link:
- 8,,,. Tobacco smoking, alcohol drinking, and cancer of the oral cavity and oropharynx among U.S. veterans. Cancer. 1993; 72: 1369–1375.Direct Link:
- 9,,. Squamous cell carcinoma of the head and neck in nonsmokers: clinical and biologic characteristics and implications for management. Curr Opin Oncol. 2001; 13: 176–182.
- 10,,, et al. Squamous cell carcinoma of the head and neck in nonsmokers and nondrinkers: an analysis of clinicopatholgic characteristics and treatment outcomes. Ann Surg Oncol. 2003; 10: 551–557.
- 11,,,,. Presence of human papillomavirus in tonsillar cancer is a favourable prognostic factor for clinical outcome. Anticancer Res. 2004; 24: 1829–1835.
- 12,. Prevalence of human papillomavirus type 16 DNA in squamous cell carcinoma of the palatine tonsil, and not the oral cavity, in young patients: a distinct clinicopathologic and molecular disease entity. Am J Surg Pathol. 2003; 27: 1463–1470.
- 13,,,,. Human papillomavirus and cancers of the upper aerodigestive tract: a review of epidemiological and experimental evidence. Cancer Epidemiol Biomarkers Prev. 1996; 5: 567–575.
- 14. Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity. Semin Oncol. 2004; 31: 744–754.
- 15,,, et al. Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study. J Natl Cancer Inst. 2003; 95: 1772–1783.
- 16,,, et al. Human papillomavirus-positive tonsillar carcinomas: a different tumor entity? Med Microbiol Immunol (Berl). 2003; 192: 129–132.
- 17,,. Human papillomavirus and head and neck cancer: epidemiology and molecular biology. Head Neck. 1998; 20: 250–265.Direct Link:
- 18,,, et al. Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck. N Engl J Med. 2001; 344: 1125–1231.
- 19,,,,,. Human papillomavirus type 16 and squamous cell carcinoma of the head and neck. Clin Cancer Res. 2002; 8: 3187–3192.
- 20,,,,,. Human papillomavirus and risk of oral cancer. Laryngoscope. 1998; 108: 1098–1103.Direct Link:
- 21,,. Role of human papillomavirus in the etiology of head and neck cancer. Head Neck. 2007; 29: 64–70.Direct Link:
- 22,,,,,. Presence of HPV in head and neck tumours: high prevalence in tonsillar localization. J Exp Clin Cancer Res. 2004; 23: 561–566.
- 23,,, et al. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med. 2007; 356: 1944–1956.
- 24,,,. Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review. Cancer Epidemiol Biomarkers Prev. 2005; 14: 467–475.
- 25. Human papillomavirus (HPV) in head and neck cancer. J Clin Virol. 2005; 32( suppl 1): S59–S66.
- 26,,,. Human papillomavirus (HPV) infections and their associations with oral disease. J Oral Pathol Med. 1991; 20: 305–317.Direct Link:
- 27,,,,. Biopsy vs. superficial scraping: detection of human papillomavirus 6, 11, 16, and 18 in potentially malignant and malignant oral lesions. J Oral Pathol Med. 2006; 35: 338–344.Direct Link:
- 28. Herpes simplex virus and human papillomavirus infections of the oral cavity. Semin Dermatol. 1994; 13: 108–117.
- 29,,, et al. Human papillomavirus in oral exfoliated cells and risk of head and neck cancer. J Natl Cancer Inst. 2004; 96: 449–455.
- 30,,,,,. Human papillomavirus and head and neck cancer: a systematic review and meta-analysis. Clin Otolaryngol. 2006; 31: 259–266.Direct Link:
- 31. HPV infections and tonsillar carcinoma. J Clin Pathol. 2004; 57: 449–455.
- 32,,. The Surveillance, Epidemiology, and End Results Program: a national resource. Cancer Epidemiol Biomarkers Prev. 1999; 8: 1117–1121.
- 33,,,,,. Human papillomavirus DNA sequences in cell lines derived from head and neck squamous cell carcinomas. Otolaryngol Head Neck Surg. 1991; 104: 303–310.
- 34,,,,. Human papillomavirus in head and neck squamous cell carcinomas in nonsmokers. Arch Otolaryngol Head Neck Surg. 1997; 123: 513–516.
- 35,,, et al. Human papillomavirus DNA in squamous cell carcinoma of the upper aerodigestive tract. Arch Otolaryngol Head Neck Surg. 1990; 116: 294–298.
- 36,,, et al. Using population-based cancer registry data to assess the burden of HPV-associated cancers in the US: overview of methods. Cancer. 2008; 113(10 suppl ): 2841–2854.Direct Link:
- 37Surveillance Research Program. National Cancer Institute SEER-Stat Software, Version 6.1.4. Bethesda, MD: National Cancer Institute; 2005.
- 38Surveillance, Epidemiology, and End Results Program. Summary staging guide for the Cancer Surveillance, Epidemiology, and End Results (SEER) Program. Bethesda, MD: National Institutes of Health, National Cancer Institute; 1977
- 39Surveillance, Epidemiology, and End Results Program. Summary staging manual 2000. Bethesda, MD: National Institutes of Health, National Cancer Institute; 2005.
- 40,,,,. Site-specific comparison of summary stage 1977 and summary stage 2000 coding. Available from URL: http://www.naaccr.org/index.asp?Col_SectionKey=11&Col_ContentID=397. Accessed on July 11, 2008.
- 41PhillipsJL, ed. Summary stage: data effects of the changes in 2000. Available from URL: http://www.naaccr.org/filesystem/pdf/Summary%20Stage%20Report%201-21-04b.pdf. Accessed on July 11, 2008.
- 42Department of Health and Human Services. Tobacco use among U.S. racial/ethnic minority groups—African-Americans, American-Indians and Alaska Natives, Asian-Americans and Pacific Islanders, and Hispanics: a report of the Surgeon General. Atlanta, GA: Centers for Disease Control and Prevention; 1998.
- 43
- 44,,. The role of tobacco, alcohol use, and body mass index in oral and pharyngeal cancer. Int J Epidemiol. 1994; 23: 1137–1144.
- 45,,,. Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the U.S. J Clin Oncol. 2008; 26: 612–618.
- 46,,. Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20-44 years. Cancer. 2005; 103: 1843–1849.Direct Link:
- 47,. Epidemiology of head and neck cancer in the U.S. Otolaryngol Head Neck Surg. 2006; 135: 451–457.
- 48,. Trends in head and neck cancer incidence in relation to smoking prevalence: an emerging epidemic of human papillomavirus-associated cancers? Cancer. 2007; 110: 1429–1435.Direct Link:
- 49,. Chapter 2: the burden of HPV-related cancers. Vaccine. 2006; 24( suppl 3): S11–S25.
- 50,,, et al. Human papillomavirus type 16 is episomal, and a high viral load may be correlated to better prognosis in tonsillar cancer. Int J Cancer. 2002; 102: 152–158.Direct Link:

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