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Original Article
Reproductive and hormonal risk factors for postmenopausal luminal, HER-2-overexpressing, and triple-negative breast cancer†
Article first published online: 25 AUG 2008
DOI: 10.1002/cncr.23786
Copyright © 2008 American Cancer Society
Additional Information
How to Cite
Phipps, A. I., Malone, K. E., Porter, P. L., Daling, J. R. and Li, C. I. (2008), Reproductive and hormonal risk factors for postmenopausal luminal, HER-2-overexpressing, and triple-negative breast cancer. Cancer, 113: 1521–1526. doi: 10.1002/cncr.23786
- †
The studies in the current analysis were both supported by the National Cancer Institute (NCI) through contracts with the Fred Hutchinson Cancer Research Center (R01 CA072787 and R01 CA85913). The work of A.I.P. in this publication was made possible by the National Center for Research Resources (NCRR; Grant No. 1 TL1 RR02501601), a component of the National Institutes of Health (NIH) and NIH Roadmap for Medical Research.
Publication History
- Issue published online: 17 SEP 2008
- Article first published online: 25 AUG 2008
- Manuscript Accepted: 15 MAY 2008
- Manuscript Revised: 6 MAY 2008
- Manuscript Received: 2 APR 2008
REFERENCES
- 1,,, et al. Molecular portraits of human breast tumours. Nature. 2000; 406: 747–752.
- 2,,, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001; 98: 10869–10874.
- 3,,, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A. 2003; 100: 8418–8423.
- 4,,, et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA. 2006; 295: 2492–2502.
- 5,,, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res. 2004; 10: 5367–5374.
- 6,,, et al. The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin Cancer Res. 2007; 13: 2329–2334.
- 7,,,,. Descriptive analysis of estrogen receptor (ER)-negative, progesterone receptor (PR)-negative, and HER2-negative invasive breast cancer, the so-called triple-negative phenotype: a population-based study from the California cancer Registry. Cancer 2007; 109: 1721–1728.Direct Link:
- 8,,, et al. Differences in risk factors for breast cancer molecular subtypes in a population-based study. Cancer Epidemiol Biomarkers Prev. 2007; 16: 439–443.
- 9,,, et al. The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. J Clin Oncol. 2002; 20: 2310–2318.
- 10,,, et al. Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. J Natl Cancer Inst. 2003; 95: 1482–1485.
- 11,,. Reproductive factors and breast cancer. Epidemiol Rev. 1993; 15: 36–47.
- 12,,,,,. Hormone-related factors and risk of breast cancer in relation to estrogen receptor and progesterone receptor status. Am J Epidemiol. 2000; 151: 703–714.
- 13,,, et al. Progesterone and estrogen receptors and mammary neoplasia in the Iowa Women's Health Study: how many kinds of breast cancer are there? Cancer Epidemiol Biomarkers Prev. 1995; 4: 319–326.
- 14,,, et al. Risk factors for hormone receptor-defined breast cancer in postmenopausal women. Cancer Epidemiol Biomarkers Prev. 2006; 15: 2482–2488.
- 15,,,. Reproductive factors and breast cancer risk according to joint estrogen and progesterone receptor status: a meta-analysis of epidemiological studies. Breast Cancer Res. 2006; 8: R43.
- 16,,, et al. Relationship between long durations and different regimens of hormone therapy and risk of breast cancer. JAMA. 2003; 289: 3254–3263.
- 17,,, et al. Relationship between menopausal hormone therapy and risk of ductal, lobular, and ductal-lobular breast carcinomas. Cancer Epidemiol Biomarker Prev. 2008; 17: 43–50.
- 18. Sampling methods for random digit dialing. J Am Stat Assoc. 1978; 73: 40–46.
- 19,. Calculation of polychotomous logistic regression parameters using individualized regressions. Biometrika. 1984; 71: 11–18.
- 20,,, et al. Reproductive factors and subtypes of breast cancer defined by hormone receptor and histology. Br J Cancer. 2005; 93: 364–371.
- 21,,, et al. Differences in breast cancer risk factors by tumor marker subtypes among premenopausal Vietnamese and Chinese women. Cancer Epidemiol Biomarkers Prev. 2005; 14: 41–47.
- 22,,, et al. Hormone replacement therapy in relation to breast carcinoma incidence rate ratios: a prospective Danish cohort study. Cancer. 2004; 100: 2328–2337.Direct Link:
- 23,,, et al. Epidemiology of basal-like breast cancer. Breast Cancer Res Treat. 2008; 109: 123–139.

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