Receipt of guideline-recommended follow-up in older colorectal cancer survivors

A Population-based Analysis

Authors

  • Gregory S. Cooper MD,

    Corresponding author
    1. Division of Gastroenterology, University Hospitals Case Medical Center, Cleveland, Ohio
    2. Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio
    • Division of Gastroenterology, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106-5066
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    • Fax: (216) 983-0347.

  • Tzuyung Doug Kou MPH, MA,

    1. Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio
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  • Harry L. Reynolds Jr MD

    1. Division of Colorectal Surgery, University Hospitals Case Medical Center, Cleveland, Ohio
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  • This study used the linked SEER-Medicare database. The interpretation and reporting of these data are the sole responsibility of the authors. The authors acknowledge the contributions of the Applied Research Program, National Cancer Institute; the Office of Research, Development and Information, Centers for Medicare and Medicaid Services; Information Management Services, Inc.; and the Surveillance, Epidemiology, and End Results (SEER) Program tumor registries in the creation of the SEER-Medicare database.

  • Presented in part at the Gastrointestinal Cancers Symposium, Orlando, Florida, January 26, 2008.

Abstract

BACKGROUND

After curative resection for colorectal cancer, routine follow-up with office visits, carcinoembryonic antigen (CEA), and colonoscopy is recommended. The actual adherence to these guidelines as well as the potential overuse of testing in routine practice has not been well studied.

METHODS

The authors identified 9426 eligible patients aged ≥66 years in a linked tumor registry-claims database who were diagnosed with adenocarcinoma of the colon or rectum from 2000 to 2001. Patients were observed to 3 years after diagnosis. Receipt of ≥2 office visits per year, ≥2 CEA tests per year (years 1 and 2), and ≥1 colonoscopy within 3 years constituted guideline fulfillment.

RESULTS

Guidelines for office visits, colonoscopy, and CEA testing were met in 92.3%, 73.6%, and 46.7% of patients, respectively. In addition, receipt of 2 nonrecommended procedures, abdominal/pelvic computed tomography scans and positron emission tomography scans, was documented in 47.7% and 6.8%, respectively. Overall, 60.2% received testing below recommended levels, 17.1% at recommended frequency, and 22.7% above guideline recommendations. In a multivariate analysis, factors associated with meeting guidelines included younger age group, white race, regional stage cancers, and poorly differentiated tumors. Considerable geographic variation in meeting guidelines was also observed.

CONCLUSIONS

Many older colorectal cancer survivors in this population-based cohort underwent testing below a minimum frequency specified by clinical practice guidelines, especially with regard to CEA. Further studies should ascertain the reasons for poor compliance and the effect on patient outcome. Cancer 2008. © 2008 American Cancer Society.

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