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Supplement
Defining a global research agenda for breast cancer†
Article first published online: 3 OCT 2008
DOI: 10.1002/cncr.23831
Copyright © 2008 American Cancer Society
Issue
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Cancer
Supplement: Guidelines for International Breast Health and Cancer Control–Implementation
Volume 113, Issue Supplement 8, pages 2366–2371, 15 October 2008
Additional Information
How to Cite
Love, R. R. (2008), Defining a global research agenda for breast cancer. Cancer, 113: 2366–2371. doi: 10.1002/cncr.23831
- †
Complete financial disclosures are presented at the end of this article.
Publication History
- Issue published online: 3 OCT 2008
- Article first published online: 3 OCT 2008
Funded by
- NIH/NCI. Grant Numbers: CA064339, CA097375
- The Breast Cancer Research Foundation
- The International Breast Cancer Research Foundation
- Abstract
- Article
- References
- Cited By
Keywords:
- breast cancer;
- research;
- global;
- international;
- developing countries;
- low and middle income countries;
- LMC;
- cost efficacy;
- technology transfer
Abstract
In contrast to western high-income nations, the incidence and mortality from breast cancer are increasing in most low and middle-income countries worldwide. Current approaches to breast cancer control developed for populations of high-income societies should not be directly transferred without evaluation. A relevant research agenda includes population differences in tumor biology and metabolization of systemic therapies, cultural and psychosocial issues, and operations in healthcare systems. Highest priority should be given to assessments of clinical downstaging and basic systemic treatment effectiveness in low and middle-income populations. Partnerships of existing organizations in high-income nations with those in low and middle-income countries are currently the most feasible sources of research support. Cancer 2008;113(8 suppl):2366–71. © 2008 American Cancer Society.

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