Fax: (212) 305-9413
Original Article
You have full text access to this OnlineOpen article
Prevalence and predictors of antioxidant supplement use during breast cancer treatment
The Long Island Breast Cancer Study Project
Article first published online: 8 JUN 2009
DOI: 10.1002/cncr.24378
Copyright © 2009 American Cancer Society
Additional Information
How to Cite
Greenlee, H., Gammon, M. D., Abrahamson, P. E., Gaudet, M. M., Terry, M. B., Hershman, D. L., Desai, M., Teitelbaum, S. L., Neugut, A. I. and Jacobson, J. S. (2009), Prevalence and predictors of antioxidant supplement use during breast cancer treatment. Cancer, 115: 3271–3282. doi: 10.1002/cncr.24378
Publication History
- Issue published online: 15 JUL 2009
- Article first published online: 8 JUN 2009
- Manuscript Accepted: 31 DEC 2008
- Manuscript Revised: 28 DEC 2008
- Manuscript Received: 15 OCT 2008
Funded by
- Lance Armstrong Foundation
- National Cancer Institute and National Institutes of Environmental Health and Sciences. Grant Numbers: U01CA/ES66572, U01CA66572, CA52283, P30ES10126
- National Cancer Institute. Grant Number: R25 CA09406
References
- 1
- 2, , . Use of alternative therapies among breast cancer outpatients compared with the general population. Altern Ther Health Med. 1999; 5: 71-76.
- 3, , , , . Current health behaviors and readiness to pursue life-style changes among men and women diagnosed with early stage prostate and breast carcinomas. Cancer. 2000; 88: 674-684.Direct Link:
- 4, . Complementary and alternative medicine use by women after completion of allopathic treatment for breast cancer. Altern Ther Health Med. 2004; 10: 52-57.
- 5, , , et al. An assessment of the utilization of complementary and alternative medication in women with gynecologic or breast malignancies. J Clin Oncol. 2004; 22: 671-677.
- 6, , , , , . Correlates of use of different types of complementary and alternative medicine by breast cancer survivors in the nurses' health study. Breast Cancer Res Treat. 2006; 100: 219-227.
- 7, , , et al. Use of complementary/alternative medicine by breast cancer survivors in Ontario: prevalence and perceptions. J Clin Oncol. 2000; 18: 2515-2521.
- 8
- 9, . Vitamin and mineral supplement use among US adults after cancer diagnosis: a systematic review. J Clin Oncol. 2008; 26: 665-673.
- 10, . Possible interactions between dietary antioxidants and chemotherapy. Oncology (Williston Park). 1999; 13: 1003-1008; discussion 1008, 1011-1012.
- 11
- 12
- 13
- 14. Use of antioxidants during chemotherapy and radiotherapy should be avoided. CA Cancer J Clin. 2005; 55: 319-321.Direct Link:
- 15
- 16, , , . Antioxidants and other nutrients do not interfere with chemotherapy or radiation therapy and can increase kill and increase survival, part 2. Altern Ther Health Med. 2007; 13: 40-47.
- 17, , , . Antioxidants and other nutrients do not interfere with chemotherapy or radiation therapy and can increase kill and increase survival, part 1. Altern Ther Health Med. 2007; 13: 22-28.
- 18, , , , , . Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy? J Natl Cancer Inst. 2008; 100: 773-783.
- 19, , , , , . Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials. Int J Cancer. 2008; 123: 1227-1239.Direct Link:
- 20, , . Free radicals and antioxidants in chemotherapy-induced toxicity. Cancer Treat Rev. 1997; 23: 209-240.
- 21, , , . Increase in free radical generation and lipid peroxidation following chemotherapy in patients with cancer. Free Radic Biol Med. 1990; 8: 15-19.
- 22. Principles of radiation therapy. In: DeVitaVT, HellmanS, RosenbergSA, eds. Cancer: Principles and Practice of Oncology. 4th ed. Philadelphia, Pa: JB Lippincott; 1993.
- 23, , , , , . Antioxidants and cancer therapy: a systematic review. J Clin Oncol. 2004; 22: 517-528.
- 24, , , et al. The Long Island Breast Cancer Study Project: description of a multi-institutional collaboration to identify environmental risk factors for breast cancer. Breast Cancer Res Treat. 2002; 74: 235-254.
- 25Wyeth Consumer Healthcare. Centrum multivitamins [package insert]. Wilmington, Del: Wyeth Consumer Healthcare; 2002. Available at: http://www.centrum.com/multi/centrum.asp Accessed on June 24, 2002.
- 26Council for Responsible Nutrition. Historical Comparison of RDIs, RDA, and DRIs, 1968 to Present for Vitamins. Washington, DC: Council for Responsible Nutrition; 2007.
- 27Council for Responsible Nutrition. Historical Comparison of RDIs, RDA, and DRIs, 1968 to Present for Minerals. Washington, DC: Council for Responsible Nutrition; 2007.
- 28Institute of Medicine, Committee on Use of Dietary Reference Intakes in Nutrition Labeling. Dietary Reference Intakes. Washington, DC: National Academy of Sciences; 2004.
- 29, , , et al. Fruits, vegetables, and micronutrient intake in relation to breast cancer survival. Breast Cancer Res Treat. 2006; 98: 199-208.
- 30. Modelling Survival Data in Medical Research. Boca Raton, Fla: Chapman & Hall/CRC; 2003.
- 31, , . Use of vitamin, mineral, nonvitamin, and nonmineral supplements in the United States: The 1987, 1992, and 2000 National Health Interview Survey results. J Am Diet Assoc. 2004; 104: 942-950.
- 32, , , et al. Prospective evaluation of vitamin E for hot flashes in breast cancer survivors. J Clin Oncol. 1998; 16: 495-500.
- 33, , , . Use of alternative medicine by women with early stage breast cancer. N Engl J Med. 1999; 340: 1733-1739.
- 34, , , . Complementary and alternative medicine use among adults: United States, 2002. Adv Data. 2004; 27: 1-19.
- 35, , , . A comparison of complementary therapy use between breast cancer patients and patients with other primary tumor sites. Am J Surg. 2000; 179: 407-411.
- 36, , , et al. Types of alternative medicine used by patients with breast, colon, or prostate cancer: predictors, motives, and costs. J Altern Complement Med. 2002; 8: 477-485.
- 37, , . Use of antioxidant supplements during breast cancer treatment: A comprehensive review. Breast Cancer Res Treat. In press.
- 38, , , et al. Randomized trial of antioxidant vitamins to prevent acute adverse effects of radiation therapy in head and neck cancer patients. J Clin Oncol. 2005; 23: 5805-5813.
- 39, , , et al. A randomized trial of antioxidant vitamins to prevent second primary cancers in head and neck cancer patients. J Natl Cancer Inst. 2005; 97: 481-488.

1097-0142/asset/olbannerleft.gif?v=1&s=ca681f5719430b26e1bc15e9ea4c9fc0a7110104)
1097-0142/asset/olbannerright.gif?v=1&s=8142566facf7e76aef9be6c51162a2e920b3b9f9)
1097-0142/asset/cover.gif?v=1&s=a7299bc18f075294c232ade468773cd0672bd470)