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Original Article
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The search for meaning—Symptoms and transvaginal sonography screening for ovarian cancer†
Predicting malignancy
Article first published online: 14 JUL 2009
DOI: 10.1002/cncr.24407
Copyright © 2009 American Cancer Society
Additional Information
How to Cite
Pavlik, E. J., Saunders, B. A., Doran, S., McHugh, K. W., Ueland, F. R., DeSimone, C. P., DePriest, P. D., Ware, R. A., Kryscio, R. J. and van Nagell, J. R. (2009), The search for meaning—Symptoms and transvaginal sonography screening for ovarian cancer. Cancer, 115: 3689–3698. doi: 10.1002/cncr.24407
- †
See editorial on pages 3606-8, this issue.
Publication History
- Issue published online: 3 AUG 2009
- Article first published online: 14 JUL 2009
- Manuscript Accepted: 26 NOV 2008
- Manuscript Revised: 4 NOV 2008
- Manuscript Received: 12 SEP 2008
Funded by
- Telford Foundation
- Department of Health and Human Services, Commonwealth of Kentucky
References
- 1, , , et al. Cancer statistics 2005. CA Cancer J Clin. 2005; 55: 10-30.Direct Link:
- 2, , , et al. Cancer statistics, 2008. CA Cancer J Clin. 2008; 58: 71-96.Direct Link:
- 3, , , et al. The accuracy of examination under anesthesia and transvaginal sonography in evaluating ovarian size. Gynecol Oncol. 2005; 99: 400-403.
- 4, , , . Ovarian carcinoma diagnosis. Results of a national ovarian cancer survey. Cancer. 2000; 89: 2068-2075.Direct Link:
- 5, , , . Frequency of symptoms of ovarian cancer in women presenting to primary care clinics. JAMA. 2004; 291: 2705-2712.
- 6, , , et al. Development of an ovarian cancer symptom index. Cancer. 2007; 109: 221-227.Direct Link:
- 7, , . Adjuvant therapy in stage I and II epithelial ovarian cancer: results of 2 prospective randomized trials. N Engl J Med. 1990; 322: 1021-1027.
- 8RiesLA, KosaryCL, HankeyBF, et al, eds. SEER Cancer Statistics Review, 1973-1995. Bethesda, Md: National Cancer Institute; 1998.
- 9, , , et al. Transabdominal ultrasound screening for early ovarian cancer. BMJ. 1989; 299: 1363-1367.
- 10, , , et al. Transvaginal sonography as a screening method for ovarian cancer: a report of the first 1000 cases screened. Cancer. 1990; 65: 573-577.Direct Link:
- 11, , , et al. Multimodal approach to screening for ovarian cancer. Lancet. 1988; 2: 268-271.
- 12, , , et al. Screening for early familial ovarian cancer with transvaginal ultrasonography and colour blood flow imaging. BMJ. 1993; 306: 1025-1029.
- 13, , , , . Transvaginal sonography as a screening method for the detection of early ovarian cancer. Gynecol Oncol. 1997; 65: 408-414.
- 14, , , , , . Outcome of a pilot randomised controlled trial of ovarian cancer screening. Lancet. 1999; 253: 1207-1210.
- 15, , , et al. Usefulness of mass screening for ovarian carcinoma using transvaginal ultrasonography. Cancer. 2000; 89: 582-588.Direct Link:
- 16, , , et al. The efficacy of transvaginal sonographic screening in asymptomatic women at risk for ovarian cancer. Gynecol Oncol. 2000; 77: 350-356.
- 17, , , et al. Ovarian cancer screening in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial: findings from the initial screen of a randomized trial. Am J Obstet Gynecol. 2005; 193: 1630-1639.
- 18, , , et al. Ovarian cancer screening with annual transvaginal sonography. Findings of 25,000 women screened. Cancer. 2007; 109: 1887-1896.Direct Link:
- 19, , , et al. Ovarian volume related to age. Gynecol Oncol. 2000; 77: 410-412.
- 20, , , , . Preoperative differentiation of malignant from benign ovarian tumors: the efficacy of morphology indexing and Doppler flow sonography. Gynecol Oncol. 2003; 91: 46-50.
- 21, , , , . Transvaginal sonographic characterization of ovarian disease: evaluation of a new scoring system to predict ovarian malignancy. Obstet Gynecol. 1991; 78: 70-76.
- 22, , , et al. A morphology index based on sonographic findings in ovarian cancer. Gynecol Oncol. 1993; 51: 7-11.
- 23, , , et al. Malignant potential of small cystic ovarian tumors in postmenopausal women. Gynecol Oncol. 1998; 69: 3-7.
- 24, , , et al. Risk of malignancy in unilocular ovarian cystic tumors less than 10 centimeters in diameter. Obstet Gynecol. 2003; 102: 594-599.
- 25, . Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine. Clin Chem. 1993; 39: 561-577.
- 26. The Statistical Evaluation of Medical Tests for Classification and Prediction. New York, NY: Oxford University Press; 2003.
- 27. An introduction to ROC analysis. Pattern Recognit Lett. 2006; 27: 861-874.
- 28. False false positive rates [letter]. N Engl J Med. 1999; 341: 131.
- 29
- 30, , , et al. Participation in transvaginal ovarian cancer screening: compliance, correlation factors, and costs. Gynecol Oncol. 1995; 57: 395-400.
- 31
- 32, , , , . Interobserver variation in ovarian measurements using transvaginal sonography. Gynecol Oncol. 1990; 39: 69-71.
- 33. Evaluation of screening program for the early detection of cancer. Statistical methods for cancer studies (edited by RG Cornell). Natl Cancer Inst Stat Textbk Monogr. 1984; 51: 267-328.
- 34. Cancer screening: degrees of proof and practical application. Cancer. 1989; 62: 1776-1789.Direct Link:
- 35, . Symptoms of ovarian cancer—where to set the bar? JAMA. 2004; 291: 2755-2756.
- 36, , , et al. Combining a symptoms index with CA 125 to improve detection of ovarian cancer. Cancer. 2008; 113: 484-489.Direct Link:
- 37, , , . Breast cancer screening: a summary of the evidence for the US Preventive Services Task Force. Ann Intern Med. 2002; 137: 347-360.
- 38, , , . Screening for breast cancer. JAMA. 2005; 293: 1245-1256.
- 39, , , et al. MRI evaluation of the contralateral breast in women with recently diagnosed breast cancer. N Engl J Med. 2007; 356: 1295-1303.
- 40, , , et al. Long-term survival and cost of treatment in patients with stage IIIC epithelial ovarian cancer. Current Women's Health Reviews. 2009; 5: 44-50.